DERL1 and TCF25

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		DERL1	TCF25
Gene Name		derlin 1	transcription factor 25 (basic helix-loop-helix)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Hrd1p Ubiquitin Ligase Complex Early Endosome Late Endosome Endoplasmic Reticulum Membrane Integral Component Of Membrane Integral Component Of Endoplasmic Reticulum Membrane	Nucleus
	Molecular Function	Protease Binding Receptor Activity Protein Binding MHC Class I Protein Binding	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding
	Biological Process	Response To Unfolded Protein Intracellular Transport Of Viral Protein In Host Cell ER-associated Ubiquitin-dependent Protein Catabolic Process Endoplasmic Reticulum Unfolded Protein Response Retrograde Protein Transport, ER To Cytosol Protein Destabilization Establishment Of Protein Localization	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Heart Development
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		10 interactors: AMFR APP CFTR HLA-A MFI2 RHO TCF25 UBXN6 VCP VIMP	8 interactors: APPBP2 CCDC155 DERL1 GPRASP2 MAGEA11 NEK2 RPS10 SAT1
Entrez ID		79139	22980
HPRD ID		12302	13830
Ensembl ID		ENSG00000136986	ENSG00000141002
Uniprot IDs		B4E1G1 Q9BUN8	Q9BQ70
PDB IDs
Enriched GO Terms of Interacting Partners?		ER-associated Ubiquitin-dependent Protein Catabolic Process Retrograde Protein Transport, ER To Cytosol Endoplasmic Reticulum Unfolded Protein Response Cellular Response To Unfolded Protein ER-nucleus Signaling Pathway Cellular Response To Topologically Incorrect Protein Response To Unfolded Protein Response To Endoplasmic Reticulum Stress Cellular Homeostasis Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Regulation Of Nitric Oxide Metabolic Process Positive Regulation Of Voltage-gated Chloride Channel Activity Positive Regulation Of Lys63-specific Deubiquitinase Activity Positive Regulation Of Protein K63-linked Deubiquitination Red, Far-red Light Phototransduction Cellular Response To Organic Substance Cellular Cation Homeostasis Cellular Ion Homeostasis Positive Regulation Of Memory T Cell Activation Synaptic Growth At Neuromuscular Junction Ubiquitin-dependent Protein Catabolic Process Cholesterol Metabolic Process Modification-dependent Protein Catabolic Process Cellular Chemical Homeostasis Collateral Sprouting In Absence Of Injury Protection From Natural Killer Cell Mediated Cytotoxicity Negative Regulation Of Immune Response Sterol Metabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Ion Homeostasis Cellular Protein Catabolic Process Negative Regulation Of Macrophage Apoptotic Process Positive Regulation Of Extracellular Matrix Disassembly Antigen Processing And Presentation Of Endogenous Peptide Antigen Via MHC Class I Via ER Pathway, TAP-independent Regulation Of Chloride Transport Negative Regulation Of Nitric-oxide Synthase Biosynthetic Process Positive Regulation Of Peptidase Activity Cell Maturation Transition Metal Ion Homeostasis Homeostatic Process Protein Catabolic Process Positive Regulation Of Plasminogen Activation Negative Regulation Of Natural Killer Cell Mediated Cytotoxicity Negative Regulation Of Acute Inflammatory Response To Antigenic Stimulus Collateral Sprouting Axon Midline Choice Point Recognition Response To Organic Substance Regulation Of Protein Deubiquitination Smooth Endoplasmic Reticulum Calcium Ion Homeostasis	Chromosome Localization To Nuclear Envelope Involved In Synapsis Negative Regulation Of Centriole-centriole Cohesion Catabolic Process Spermidine Acetylation Establishment Of Localization In Cell Regulation Of Centriole-centriole Cohesion Putrescine Catabolic Process Cellular Macromolecule Catabolic Process Viral Life Cycle Intracellular Protein Transport Meiotic Cell Cycle Regulation Of Mitotic Centrosome Separation Oxalate Transport Intracellular Transport Of Viral Protein In Host Cell Retrograde Protein Transport, ER To Cytosol Chromosome Segregation Cellular Localization Polyamine Catabolic Process 3'-phosphoadenosine 5'-phosphosulfate Biosynthetic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Neurotransmitter Uptake Cellular Protein Localization Protein Transport Centrosome Separation 3'-phosphoadenosine 5'-phosphosulfate Metabolic Process Establishment Of Protein Localization Polyamine Biosynthetic Process Intracellular Transport Mitotic Spindle Assembly Regulation Of Attachment Of Spindle Microtubules To Kinetochore Amine Biosynthetic Process Ubiquitin-dependent Protein Catabolic Process Protein Destabilization Modification-dependent Protein Catabolic Process Intracellular Transport Of Virus Viral Process Proteolysis Involved In Cellular Protein Catabolic Process Polyamine Metabolic Process Cellular Protein Catabolic Process Protein Localization Protein Catabolic Process Sulfate Transmembrane Transport ER-associated Ubiquitin-dependent Protein Catabolic Process Establishment Of Chromosome Localization Sulfate Transport Mitotic Spindle Organization Negative Regulation Of DNA Binding Regulation Of Centrosome Cycle Neutral Amino Acid Transport
Tagcloud ?		apparatus cdt cdts chimeras complementation cytolethal derl2 derlin dispensable distending ducreyi erad evasion exit exotoxins exploited haemophilus hrd1 intoxication p97 reaching retrograde retrotranslocation ricin toxins trafficked uncharacterized undescribed wr
Tagcloud (Difference) ?		apparatus cdt cdts chimeras complementation cytolethal derl2 derlin dispensable distending ducreyi erad evasion exit exotoxins exploited haemophilus hrd1 intoxication p97 reaching retrograde retrotranslocation ricin toxins trafficked uncharacterized undescribed wr
Tagcloud (Intersection) ?