TCF25

Description		TCF25 ribosome quality control complex subunit
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol RQC Complex
	Molecular Function	Protein Binding
	Biological Process	Regulation Of Protein K48-linked Ubiquitination Rescue Of Stalled Ribosome
Pathways		Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide
Drugs
Diseases
GWAS		Blond vs. brown/black hair color ( 30531825) Brain morphology (MOSTest) ( 32665545) Brown vs. black hair color ( 30531825) Cutaneous squamous cell carcinoma ( 32041948) High light scatter reticulocyte count ( 27863252 32888494) High light scatter reticulocyte percentage of red cells ( 27863252 32888494) Monobrow ( 27182965) Red vs. brown/black hair color ( 30531825) Reticulocyte count ( 27863252 32888494) Reticulocyte fraction of red cells ( 27863252 32888494) Rosacea symptom severity ( 29771307) White matter integrity (fractional anisotropy) ( 32358547)
Novel Interacting Genes		1 novel interacting genes: TUBB3
Interacting Genes		13 interacting genes: APPBP2 DERL1 GPRASP2 GPX7 KASH5 LRRK1 MAGEA11 NEK2 PTEN RPS10 SAT1 SHANK3 USP40
Entrez ID		22980
HPRD ID		13830
Ensembl ID		ENSG00000141002
Uniprot IDs		Q9BQ70
PDB IDs
Enriched GO Terms of Interacting Partners?		Postsynaptic Density Assembly Postsynaptic Specialization Assembly Spindle Assembly Postsynaptic Density Organization Dendritic Spine Morphogenesis Ubiquitin-specific Protease Binding Postsynaptic Specialization Organization Spindle Organization Positive Regulation Of Excitatory Postsynaptic Potential Dendritic Spine Organization Microtubule Cytoskeleton Organization Neuron Projection Organization Postsynapse Organization Negative Regulation Of Centriole-centriole Cohesion Negative Regulation Of Synaptic Vesicle Clustering Modulation Of Excitatory Postsynaptic Potential Spermidine Binding Social Behavior Membraneless Organelle Assembly Phosphatidylinositol-3,4-bisphosphate 3-phosphatase Activity Negative Regulation Of Keratinocyte Migration Inositol-1,3,4,5-tetrakisphosphate 3-phosphatase Activity Inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase Activity Spermidine Acetylation Putrescine Catabolic Process Netrin Receptor Binding Derlin-1-VIMP Complex Guanylate Kinase-associated Protein Clustering Meiotic Spindle Pole Catalase Activity Regulation Of Centriole-centriole Cohesion Microtubule Organelle Assembly Central Nervous System Myelin Maintenance Rhythmic Synaptic Transmission Regulation Of Cell Size Diamine N-acetyltransferase Activity Positive Regulation Of Synapse Structural Plasticity Striatal Medium Spiny Neuron Differentiation Intercellular Bridge Microtubule-based Process Regulation Of Protein Stability Negative Regulation Of Wound Healing, Spreading Of Epidermal Cells Synapse Assembly Polyamine Catabolic Process Synaptic Receptor Adaptor Activity Meiotic Cell Cycle Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase Activity Myelin Sheath Adaxonal Region Phosphatidylinositol Phosphate Phosphatase Activity
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