RABEPK and PRKRA

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		RABEPK	PRKRA
Gene Name		Rab9 effector protein with kelch motifs	protein kinase, interferon-inducible double stranded RNA dependent activator
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Endosome Plasma Membrane Endosome Membrane Intracellular Membrane-bounded Organelle	Nucleoplasm Cytoplasm Cytosol Membrane Perinuclear Region Of Cytoplasm
	Molecular Function		Protein Binding Enzyme Activator Activity Protein Homodimerization Activity Poly(A) RNA Binding
	Biological Process	Receptor-mediated Endocytosis Vesicle Docking Involved In Exocytosis	Protein Phosphorylation Immune Response Negative Regulation Of Cell Proliferation Response To Virus Gene Expression Production Of SiRNA Involved In RNA Interference Cellular Response To Oxidative Stress Outer Ear Morphogenesis Middle Ear Morphogenesis Positive Regulation Of Catalytic Activity Skeletal System Morphogenesis Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways			Regulatory RNA pathways MicroRNA (miRNA) biogenesis Small interfering RNA (siRNA) biogenesis
Drugs
Diseases
GWAS			Multiple sclerosis (OCB status) ( 23472185)
Protein-Protein Interactions		7 interactors: GLUL PIKFYVE POR PRKRA RAB9A TMEM98 ZYX	21 interactors: AGO2 CEBPZ COPS6 DICER1 EIF2AK2 GDF9 KIAA1377 LYAR NKRF POLR2G RABEPK RB1 SETDB1 SHC1 SNX5 TARBP2 TIRAP TP53 ZFP28 ZMAT3 ZNF746
Entrez ID		10244	8575
HPRD ID		09337	04573
Ensembl ID		ENSG00000136933	ENSG00000180228
Uniprot IDs		Q7Z6M1	B4DJC7 O75569
PDB IDs			2DIX
Enriched GO Terms of Interacting Partners?		Retrograde Transport, Endosome To Golgi Cellular Organofluorine Metabolic Process Nitrate Catabolic Process Nitric Oxide Catabolic Process Cellular Response To Stimulus Glutamine Biosynthetic Process Regulation Of Growth Plate Cartilage Chondrocyte Proliferation Nitrate Metabolic Process Lipid Modification Endosomal Transport Response To Organic Substance Glutamate Catabolic Process Positive Regulation Of Cholesterol Biosynthetic Process Response To Stimulus Positive Regulation Of Cholesterol Metabolic Process Positive Regulation Of Steroid Hormone Biosynthetic Process Outer Ear Morphogenesis Positive Regulation Of Hormone Biosynthetic Process Positive Regulation Of Secretion Production Of SiRNA Involved In RNA Interference Neurotransmitter Uptake Dicarboxylic Acid Catabolic Process Carnitine Metabolic Process Stress Fiber Assembly RNA Interference Cellular Response To Follicle-stimulating Hormone Stimulus Regulation Of Cell Proliferation Amino-acid Betaine Metabolic Process Response To Nutrient Levels Negative Regulation Of Lipase Activity Regulation Of Cholesterol Biosynthetic Process Response To Extracellular Stimulus Response To Follicle-stimulating Hormone Phosphatidylinositol-3-phosphate Biosynthetic Process Cellular Response To Gonadotropin Stimulus Positive Regulation Of Synaptic Transmission, Glutamatergic Glutamate Metabolic Process Flavonoid Metabolic Process Positive Regulation Of Monooxygenase Activity Regulation Of Hormone Biosynthetic Process Positive Regulation Of Steroid Metabolic Process Middle Ear Morphogenesis Nitric Oxide Metabolic Process Regulation Of Cholesterol Metabolic Process Reactive Nitrogen Species Metabolic Process Positive Regulation Of Chondrocyte Differentiation Response To External Stimulus Cellular Response To Organic Substance Myelin Assembly Regulation Of Hormone Metabolic Process	RNA Interference Pre-miRNA Processing Production Of MiRNAs Involved In Gene Silencing By MiRNA Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Gene Expression Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Posttranscriptional Regulation Of Gene Expression RNA Metabolic Process Positive Regulation Of Cellular Metabolic Process Gene Silencing By MiRNA Targeting Of MRNA For Destruction Involved In RNA Interference Cellular Response To DsRNA Regulation Of Gene Expression Posttranscriptional Gene Silencing Gene Expression Production Of SiRNA Involved In RNA Interference Regulation Of Transcription, DNA-templated Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of Viral Process Negative Regulation Of Biosynthetic Process RNA Biosynthetic Process Gene Silencing By RNA Glial Cell Apoptotic Process Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Metabolic Process Response To DsRNA Regulation Of Viral Genome Replication Regulation Of Protein Metabolic Process Regulation Of Translational Initiation Positive Regulation Of Nuclear-transcribed MRNA Poly(A) Tail Shortening Positive Regulation Of Protein Metabolic Process Regulation Of Phosphorylation Nucleobase-containing Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Positive Regulation Of MRNA 3'-end Processing Gene Silencing Regulation Of Translation Viral Process Regulation Of Metabolic Process Regulation Of MRNA 3'-end Processing ER-nucleus Signaling Pathway Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Cellular Protein Metabolic Process Regulation Of Growth Regulation Of Phosphorus Metabolic Process Regulation Of Cell Proliferation
Tagcloud ?			1q21 5q31 6p21 alleles anxa6 applicable atopic conduct dermatitis direction exclusive histocompatibility immunochip influencing loci methodologies mutually opposing overlap overlapping pleiotropic psoriasis rarely shared th2 tnip1 traits unreported utilizing
Tagcloud (Difference) ?			1q21 5q31 6p21 alleles anxa6 applicable atopic conduct dermatitis direction exclusive histocompatibility immunochip influencing loci methodologies mutually opposing overlap overlapping pleiotropic psoriasis rarely shared th2 tnip1 traits unreported utilizing
Tagcloud (Intersection) ?