SF1 and PNRC2

Number of citations of the paper that reports this interaction (PMID 11574675)
11

Data Source:
BioGRID (two hybrid)

		SF1	PNRC2
Gene Name		splicing factor 1	proline-rich nuclear receptor coactivator 2
Image
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex Ribosome	Cytoplasmic MRNA Processing Body Nucleus
	Molecular Function	Transcription Corepressor Activity RNA Binding Zinc Ion Binding Poly(A) RNA Binding	Protein Binding
	Biological Process	Spliceosomal Complex Assembly MRNA 3'-splice Site Recognition MRNA Splicing, Via Spliceosome Transcription, DNA-templated Regulation Of Transcription, DNA-templated Male Sex Determination Leydig Cell Differentiation Negative Regulation Of Smooth Muscle Cell Proliferation Regulation Of Steroid Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Transcription, DNA-templated Regulation Of Transcription, DNA-templated Deadenylation-independent Decapping Of Nuclear-transcribed MRNA
Pathways
Drugs
Diseases
GWAS		Urate levels ( 21768215)	Obesity-related traits ( 23251661)
Protein-Protein Interactions		45 interactors: APBB1 ATXN1 BCAS2 BCL2 CIAO1 DDX17 EFTUD2 ESR1 EWSR1 FAM168A FUS GAS7 HNRNPF HNRNPH1 HNRNPH2 HNRNPK HNRNPUL1 IL7R ILF3 ITCH KRTAP26-1 MKRN3 NFKB1 PLSCR1 PNRC2 PRKG1 PRPF40A PSMA3 RBM10 RBM17 RBM4 RBM7 RBPMS SF3A1 SF3B4 TAF15 TCERG1 TRIM23 TRIM69 U2AF2 WBP4 WDR77 WDR83 WWP2 ZNF461	20 interactors: AR DCP1A ESR1 ESR2 ESRRA ESRRG GLOD4 HNF4A HNF4G NR5A1 NR5A2 RARA RARG RORA RORB SF1 SPAG9 XRCC6 ZBTB16 ZBTB48
Entrez ID		7536	55629
HPRD ID		03306	17871
Ensembl ID		ENSG00000168066	ENSG00000189266
Uniprot IDs		Q15637	Q9NPJ4
PDB IDs		1K1G 1OPI 2M09 2M0G 4FXW 4FXX	4B6H
Enriched GO Terms of Interacting Partners?		RNA Processing RNA Splicing MRNA Processing MRNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Gene Expression RNA Metabolic Process Cellular Aromatic Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Nitrogen Compound Metabolic Process Cellular Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Gene Expression Regulation Of RNA Metabolic Process Regulation Of Metabolic Process Metabolic Process Transcription, DNA-templated Regulation Of RNA Splicing RNA Biosynthetic Process Cellular Process Positive Regulation Of Gene Expression Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Metabolic Process Protein Ubiquitination Cellular Macromolecule Biosynthetic Process Response To Virus Positive Regulation Of Cellular Metabolic Process Protein Modification By Small Protein Conjugation Macromolecule Biosynthetic Process Defense Response To Virus Regulation Of MRNA Splicing, Via Spliceosome Protein Polyubiquitination Regulation Of Viral Genome Replication Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Viral Process Positive Regulation Of Transcription, DNA-templated Regulation Of MRNA Processing Transcription From RNA Polymerase II Promoter Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Cell Activation Apoptotic Process Response To Other Organism	Steroid Hormone Mediated Signaling Pathway Hormone-mediated Signaling Pathway Cellular Response To Steroid Hormone Stimulus Transcription Initiation From RNA Polymerase II Promoter Intracellular Receptor Signaling Pathway DNA-templated Transcription, Initiation Cellular Response To Organic Cyclic Compound Cellular Response To Lipid Response To Steroid Hormone Cellular Response To Hormone Stimulus Transcription From RNA Polymerase II Promoter Response To Lipid Response To Organic Cyclic Compound Response To Hormone Positive Regulation Of Transcription, DNA-templated Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter RNA Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process RNA Metabolic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Gene Expression Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Nucleobase-containing Compound Metabolic Process Cellular Response To Organic Substance Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Nitrogen Compound Metabolic Process Organ Development Response To Organic Substance Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process System Development Developmental Process Involved In Reproduction Prostate Gland Development Sex Differentiation Multicellular Organismal Development Anatomical Structure Development Regulation Of Metabolic Process
Tagcloud ?		aaggtcagaaat aromatase belong br clones coup decided differently dnase ear encode err footprinting hybrid mobility ovary p120e4f promoters s1 shorter silencer situated sk specimen superfamily tf1 variant ws3tf	2d af alternatives biologically circular coactivators cognate competitive confirms constitutes coregulator coregulators dichroism ecd eralpha eralpha17p exception exhaustive governing grb2 issued motifs polyproline ppii pxxp sh3 spectroscopy transductions
Tagcloud (Difference) ?		aaggtcagaaat aromatase belong br clones coup decided differently dnase ear encode err footprinting hybrid mobility ovary p120e4f promoters s1 shorter silencer situated sk specimen superfamily tf1 variant ws3tf	2d af alternatives biologically circular coactivators cognate competitive confirms constitutes coregulator coregulators dichroism ecd eralpha eralpha17p exception exhaustive governing grb2 issued motifs polyproline ppii pxxp sh3 spectroscopy transductions
Tagcloud (Intersection) ?