SF1 and SF3A1

Number of citations of the paper that reports this interaction (PMID 22365833)
24

Data Source:
BioGRID (two hybrid, two hybrid)

		SF1	SF3A1
Gene Name		splicing factor 1	splicing factor 3a, subunit 1, 120kDa
Image
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex Ribosome	Nucleoplasm Spliceosomal Complex U2-type Spliceosomal Complex Catalytic Step 2 Spliceosome
	Molecular Function	Transcription Corepressor Activity RNA Binding Zinc Ion Binding Poly(A) RNA Binding	RNA Binding Protein Binding Poly(A) RNA Binding
	Biological Process	Spliceosomal Complex Assembly MRNA 3'-splice Site Recognition MRNA Splicing, Via Spliceosome Transcription, DNA-templated Regulation Of Transcription, DNA-templated Male Sex Determination Leydig Cell Differentiation Negative Regulation Of Smooth Muscle Cell Proliferation Regulation Of Steroid Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription	MRNA 3'-splice Site Recognition MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing Gene Expression
Pathways			Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Urate levels ( 21768215)
Protein-Protein Interactions		45 interactors: APBB1 ATXN1 BCAS2 BCL2 CIAO1 DDX17 EFTUD2 ESR1 EWSR1 FAM168A FUS GAS7 HNRNPF HNRNPH1 HNRNPH2 HNRNPK HNRNPUL1 IL7R ILF3 ITCH KRTAP26-1 MKRN3 NFKB1 PLSCR1 PNRC2 PRKG1 PRPF40A PSMA3 RBM10 RBM17 RBM4 RBM7 RBPMS SF3A1 SF3B4 TAF15 TCERG1 TRIM23 TRIM69 U2AF2 WBP4 WDR77 WDR83 WWP2 ZNF461	18 interactors: APBB1 CSNK2A1 DDX42 GAS7 IL7R PRPF40A RBFOX2 RBM10 SF1 SF3A2 SF3A3 SMAD3 SMURF1 SP1 TCERG1 UBC WBP4 WDR77
Entrez ID		7536	10291
HPRD ID		03306	06903
Ensembl ID		ENSG00000168066	ENSG00000099995
Uniprot IDs		Q15637	E9PAW1 Q15459
PDB IDs		1K1G 1OPI 2M09 2M0G 4FXW 4FXX	1ZKH 2DT6 2DT7
Enriched GO Terms of Interacting Partners?		RNA Processing RNA Splicing MRNA Processing MRNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Gene Expression RNA Metabolic Process Cellular Aromatic Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Nitrogen Compound Metabolic Process Cellular Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Gene Expression Regulation Of RNA Metabolic Process Regulation Of Metabolic Process Metabolic Process Transcription, DNA-templated Regulation Of RNA Splicing RNA Biosynthetic Process Cellular Process Positive Regulation Of Gene Expression Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Metabolic Process Protein Ubiquitination Cellular Macromolecule Biosynthetic Process Response To Virus Positive Regulation Of Cellular Metabolic Process Protein Modification By Small Protein Conjugation Macromolecule Biosynthetic Process Defense Response To Virus Regulation Of MRNA Splicing, Via Spliceosome Protein Polyubiquitination Regulation Of Viral Genome Replication Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Viral Process Positive Regulation Of Transcription, DNA-templated Regulation Of MRNA Processing Transcription From RNA Polymerase II Promoter Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Cell Activation Apoptotic Process Response To Other Organism	RNA Splicing RNA Processing MRNA Processing RNA Metabolic Process MRNA Metabolic Process MRNA 3'-splice Site Recognition Gene Expression Nucleobase-containing Compound Metabolic Process Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Cellular Response To Growth Factor Stimulus Nitrogen Compound Metabolic Process Transforming Growth Factor Beta Receptor Signaling Pathway MRNA Splice Site Selection Cellular Macromolecular Complex Assembly Transcription Initiation From RNA Polymerase II Promoter Ribonucleoprotein Complex Assembly Cellular Response To Transforming Growth Factor Beta Stimulus Regulation Of Cellular Response To Growth Factor Stimulus Response To Transforming Growth Factor Beta Spliceosomal Complex Assembly Negative Regulation Of Cell Cycle DNA-templated Transcription, Initiation Regulation Of Transcription From RNA Polymerase II Promoter Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Regulation Of Cell Cycle Cell Differentiation Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Rhythmic Process Regulation Of RNA Metabolic Process Ribonucleoprotein Complex Biogenesis Cell Cycle Arrest Positive Regulation Of Wnt Signaling Pathway Negative Regulation Of Biosynthetic Process Cell Cycle Transcription From RNA Polymerase II Promoter Intracellular Receptor Signaling Pathway Gland Development Cellular Metabolic Process Negative Regulation Of BMP Signaling Pathway
Tagcloud ?		aaggtcagaaat aromatase belong br clones coup decided differently dnase ear encode err footprinting hybrid mobility ovary p120e4f promoters s1 shorter silencer situated sk specimen superfamily tf1 variant ws3tf	actb aging analysed comprehensive cows deltact differed dominant durations eif2b2 follicle follicles follicular fsh gapdh genorm geometric granulosa maternal normfinder preovulatory programs ranking reference reffinder rnf20 suitable threshold ube2d2
Tagcloud (Difference) ?		aaggtcagaaat aromatase belong br clones coup decided differently dnase ear encode err footprinting hybrid mobility ovary p120e4f promoters s1 shorter silencer situated sk specimen superfamily tf1 variant ws3tf	actb aging analysed comprehensive cows deltact differed dominant durations eif2b2 follicle follicles follicular fsh gapdh genorm geometric granulosa maternal normfinder preovulatory programs ranking reference reffinder rnf20 suitable threshold ube2d2
Tagcloud (Intersection) ?