SF1 and CIAO1

Number of citations of the paper that reports this interaction (PMID 23891004)
4

Data Source:
BioGRID (two hybrid, affinity chromatography technology)

		SF1	CIAO1
Gene Name		splicing factor 1	cytosolic iron-sulfur assembly component 1
Image
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex Ribosome	MMXD Complex CIA Complex
	Molecular Function	Transcription Corepressor Activity RNA Binding Zinc Ion Binding Poly(A) RNA Binding
	Biological Process	Spliceosomal Complex Assembly MRNA 3'-splice Site Recognition MRNA Splicing, Via Spliceosome Transcription, DNA-templated Regulation Of Transcription, DNA-templated Male Sex Determination Leydig Cell Differentiation Negative Regulation Of Smooth Muscle Cell Proliferation Regulation Of Steroid Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription	Regulation Of Transcription From RNA Polymerase II Promoter Chromosome Segregation Positive Regulation Of Cell Proliferation Iron-sulfur Cluster Assembly Small Molecule Metabolic Process
Pathways			Cytosolic iron-sulfur cluster assembly
Drugs
Diseases
GWAS		Urate levels ( 21768215)
Protein-Protein Interactions		45 interactors: APBB1 ATXN1 BCAS2 BCL2 CIAO1 DDX17 EFTUD2 ESR1 EWSR1 FAM168A FUS GAS7 HNRNPF HNRNPH1 HNRNPH2 HNRNPK HNRNPUL1 IL7R ILF3 ITCH KRTAP26-1 MKRN3 NFKB1 PLSCR1 PNRC2 PRKG1 PRPF40A PSMA3 RBM10 RBM17 RBM4 RBM7 RBPMS SF3A1 SF3B4 TAF15 TCERG1 TRIM23 TRIM69 U2AF2 WBP4 WDR77 WDR83 WWP2 ZNF461	8 interactors: APP FAM96A FAM96B GOLM1 MEOX1 SF1 SRPK1 WT1
Entrez ID		7536	9391
HPRD ID		03306	16057
Ensembl ID		ENSG00000168066
Uniprot IDs		Q15637	O76071
PDB IDs		1K1G 1OPI 2M09 2M0G 4FXW 4FXX	3FM0
Enriched GO Terms of Interacting Partners?		RNA Processing RNA Splicing MRNA Processing MRNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Gene Expression RNA Metabolic Process Cellular Aromatic Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Nitrogen Compound Metabolic Process Cellular Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Gene Expression Regulation Of RNA Metabolic Process Regulation Of Metabolic Process Metabolic Process Transcription, DNA-templated Regulation Of RNA Splicing RNA Biosynthetic Process Cellular Process Positive Regulation Of Gene Expression Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Metabolic Process Protein Ubiquitination Cellular Macromolecule Biosynthetic Process Response To Virus Positive Regulation Of Cellular Metabolic Process Protein Modification By Small Protein Conjugation Macromolecule Biosynthetic Process Defense Response To Virus Regulation Of MRNA Splicing, Via Spliceosome Protein Polyubiquitination Regulation Of Viral Genome Replication Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Viral Process Positive Regulation Of Transcription, DNA-templated Regulation Of MRNA Processing Transcription From RNA Polymerase II Promoter Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Cell Activation Apoptotic Process Response To Other Organism	Negative Regulation Of Female Gonad Development Positive Regulation Of Male Gonad Development Regulation Of Female Gonad Development RNA Processing Sex Determination Iron-sulfur Cluster Assembly Chromosome Segregation Adrenal Gland Development RNA Splicing Positive Regulation Of Transcription From RNA Polymerase II Promoter Reproduction MRNA Processing Negative Regulation Of Metanephric Glomerular Mesangial Cell Proliferation Embryonic Pattern Specification Reproductive Process Positive Regulation Of Transcription, DNA-templated MRNA Metabolic Process Positive Regulation Of Metanephric Ureteric Bud Development Thorax And Anterior Abdomen Determination Visceral Serous Pericardium Development Synaptic Growth At Neuromuscular Junction Posterior Mesonephric Tubule Development Adrenal Cortex Formation Segmentation Nucleus Organization Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Negative Regulation Of Glomerulus Development Collateral Sprouting In Absence Of Injury Negative Regulation Of Glomerular Mesangial Cell Proliferation Male Gonad Development Positive Regulation Of Cellular Biosynthetic Process Primary Sex Determination Zygotic Determination Of Anterior/posterior Axis, Embryo Negative Regulation Of Mesenchymal Cell Apoptotic Process Involved In Metanephros Development Sclerotome Development Developmental Process Involved In Reproduction Collateral Sprouting Axon Midline Choice Point Recognition MRNA 3'-splice Site Recognition Negative Regulation Of Cell Proliferation Involved In Kidney Development Male Sex Differentiation RNA Metabolic Process Sexual Reproduction Regulation Of Transcription From RNA Polymerase II Promoter Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Somite Specification Cardiac Muscle Cell Fate Commitment Intracellular Receptor Signaling Pathway Multicellular Organismal Reproductive Process
Tagcloud ?		aaggtcagaaat aromatase belong br clones coup decided differently dnase ear encode err footprinting hybrid mobility ovary p120e4f promoters s1 shorter silencer situated sk specimen superfamily tf1 variant ws3tf
Tagcloud (Difference) ?		aaggtcagaaat aromatase belong br clones coup decided differently dnase ear encode err footprinting hybrid mobility ovary p120e4f promoters s1 shorter silencer situated sk specimen superfamily tf1 variant ws3tf
Tagcloud (Intersection) ?