SF1 and RBM10

Number of citations of the paper that reports this interaction (PMID 22365833)
24

Data Source:
BioGRID (two hybrid, two hybrid)

		SF1	RBM10
Gene Name		splicing factor 1	RNA binding motif protein 10
Image
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex Ribosome	Nucleus Nucleoplasm
	Molecular Function	Transcription Corepressor Activity RNA Binding Zinc Ion Binding Poly(A) RNA Binding	Nucleotide Binding Protein Binding Zinc Ion Binding Protein Complex Binding Identical Protein Binding Poly(A) RNA Binding
	Biological Process	Spliceosomal Complex Assembly MRNA 3'-splice Site Recognition MRNA Splicing, Via Spliceosome Transcription, DNA-templated Regulation Of Transcription, DNA-templated Male Sex Determination Leydig Cell Differentiation Negative Regulation Of Smooth Muscle Cell Proliferation Regulation Of Steroid Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription	MRNA Processing Biological_process RNA Splicing
Pathways
Drugs
Diseases
GWAS		Urate levels ( 21768215)
Protein-Protein Interactions		45 interactors: APBB1 ATXN1 BCAS2 BCL2 CIAO1 DDX17 EFTUD2 ESR1 EWSR1 FAM168A FUS GAS7 HNRNPF HNRNPH1 HNRNPH2 HNRNPK HNRNPUL1 IL7R ILF3 ITCH KRTAP26-1 MKRN3 NFKB1 PLSCR1 PNRC2 PRKG1 PRPF40A PSMA3 RBM10 RBM17 RBM4 RBM7 RBPMS SF3A1 SF3B4 TAF15 TCERG1 TRIM23 TRIM69 U2AF2 WBP4 WDR77 WDR83 WWP2 ZNF461	21 interactors: AES ATN1 CCAR1 CSNK2A1 DDX5 FAM124A HNRNPH2 HNRNPK IK NHP2L1 PRCC PTBP1 PTBP2 RBM4 SF1 SF3A1 SREK1 SRSF6 TBC1D22B U2AF1 UBQLN4
Entrez ID		7536	8241
HPRD ID		03306	02095
Ensembl ID		ENSG00000168066	ENSG00000182872
Uniprot IDs		Q15637	P98175 Q7Z3D7
PDB IDs		1K1G 1OPI 2M09 2M0G 4FXW 4FXX	2LXI 2M2B
Enriched GO Terms of Interacting Partners?		RNA Processing RNA Splicing MRNA Processing MRNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Gene Expression RNA Metabolic Process Cellular Aromatic Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Nitrogen Compound Metabolic Process Cellular Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Gene Expression Regulation Of RNA Metabolic Process Regulation Of Metabolic Process Metabolic Process Transcription, DNA-templated Regulation Of RNA Splicing RNA Biosynthetic Process Cellular Process Positive Regulation Of Gene Expression Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Metabolic Process Protein Ubiquitination Cellular Macromolecule Biosynthetic Process Response To Virus Positive Regulation Of Cellular Metabolic Process Protein Modification By Small Protein Conjugation Macromolecule Biosynthetic Process Defense Response To Virus Regulation Of MRNA Splicing, Via Spliceosome Protein Polyubiquitination Regulation Of Viral Genome Replication Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Viral Process Positive Regulation Of Transcription, DNA-templated Regulation Of MRNA Processing Transcription From RNA Polymerase II Promoter Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Cell Activation Apoptotic Process Response To Other Organism	RNA Splicing MRNA Processing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions MRNA Metabolic Process RNA Processing RNA Metabolic Process Gene Expression Regulation Of Alternative MRNA Splicing, Via Spliceosome Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of RNA Splicing Cellular Nitrogen Compound Metabolic Process MRNA Splice Site Selection Nitrogen Compound Metabolic Process Spliceosomal Complex Assembly Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of RNA Splicing Regulation Of MRNA Processing Ribonucleoprotein Complex Biogenesis MRNA 3'-splice Site Recognition Ribonucleoprotein Complex Assembly Negative Regulation Of Cellular Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process Negative Regulation Of Gene Expression Rhythmic Process Negative Regulation Of MRNA Splicing, Via Spliceosome Cellular Macromolecule Biosynthetic Process Regulation Of RNA Metabolic Process Macromolecule Biosynthetic Process Termination Of RNA Polymerase II Transcription Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Cellular Metabolic Process MRNA Export From Nucleus Cellular Macromolecular Complex Assembly DNA-templated Transcription, Termination Regulation Of Lipid Transport By Positive Regulation Of Transcription From RNA Polymerase II Promoter RNA Export From Nucleus Regulation Of Metabolic Process MRNA 3'-end Processing Biosynthetic Process Primary Sex Determination Positive Regulation Of Low-density Lipoprotein Particle Receptor Biosynthetic Process Positive Regulation Of Anoikis RNA 3'-end Processing Negative Regulation Of Biosynthetic Process IRES-dependent Translational Initiation
Tagcloud ?		aaggtcagaaat aromatase belong br clones coup decided differently dnase ear encode err footprinting hybrid mobility ovary p120e4f promoters s1 shorter silencer situated sk specimen superfamily tf1 variant ws3tf	abcc12 braf dabrafenib deregulated deserve detoxification discover exploratory highlighted invasiveness klf17 melanoma mtefd1 nqo1 peaks responder responders rin1 seldi silico slain1 strongest surrogates tox3 tspo2 v600 vemurafenib z zbtb44
Tagcloud (Difference) ?		aaggtcagaaat aromatase belong br clones coup decided differently dnase ear encode err footprinting hybrid mobility ovary p120e4f promoters s1 shorter silencer situated sk specimen superfamily tf1 variant ws3tf	abcc12 braf dabrafenib deregulated deserve detoxification discover exploratory highlighted invasiveness klf17 melanoma mtefd1 nqo1 peaks responder responders rin1 seldi silico slain1 strongest surrogates tox3 tspo2 v600 vemurafenib z zbtb44
Tagcloud (Intersection) ?