PNRC2 and ZBTB48

Number of citations of the paper that reports this interaction (PubMedID 21900206)
0

Data Source:
BioGRID (two hybrid)

		PNRC2	ZBTB48
Description		proline rich nuclear receptor coactivator 2	zinc finger and BTB domain containing 48
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GO Annotations	Cellular Component	P-body Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Cytosol	Chromosome, Telomeric Region Nucleus Chromosome
	Molecular Function	Protein Binding	Transcription Cis-regulatory Region Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA Binding Double-stranded Telomeric DNA Binding DNA-binding Transcription Factor Activity RNA Binding Protein Binding Zinc Ion Binding Identical Protein Binding Sequence-specific DNA Binding Metal Ion Binding
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay MRNA Metabolic Process Deadenylation-independent Decapping Of Nuclear-transcribed MRNA	Regulation Of Transcription By RNA Polymerase II Telomere Maintenance Via Telomere Lengthening Positive Regulation Of DNA-templated Transcription Regulation Of RNA Metabolic Process
Pathways		Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)	Body size at age 10 ( 32376654)
Interacting Genes		23 interacting genes: APP AR BANP DCP1A ESR1 ESR2 ESRRA ESRRG FBXO7 GALK1 GLOD4 HNF4A HNF4G NR5A1 NR5A2 RARA RARG RORA RORB SPAG9 XRCC6 ZBTB16 ZBTB48	35 interacting genes: C11orf58 CDK2AP2 CDKN1A CEP70 DVL2 DVL3 EP300 GPATCH2L ILK KRTAP1-1 KRTAP10-5 KRTAP10-7 L3MBTL2 LLCFC1 MAP1LC3A MCC NME7 PNRC2 RGS2 RNF10 SPANXN2 THAP1 TNFRSF14 TRIM41 TSPYL2 UPF2 WDR5 ZBTB26 ZBTB6 ZBTB7A ZBTB8A ZBTB9 ZNF317 ZNF408 ZNF837
Entrez ID		55629	3104
HPRD ID		17871	01316
Ensembl ID		ENSG00000189266	ENSG00000204859
Uniprot IDs		Q9NPJ4	A8K291 B2R702 P10074
PDB IDs		4B6H 5KQ1 5KQ4	3B84 5YJ3
Enriched GO Terms of Interacting Partners?		Nuclear Receptor Activity Intracellular Receptor Signaling Pathway Sequence-specific DNA Binding DNA-binding Transcription Factor Activity Positive Regulation Of Transcription By RNA Polymerase II Hormone-mediated Signaling Pathway Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription DNA Binding Positive Regulation Of RNA Metabolic Process Estrogen Response Element Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Positive Regulation Of Nucleobase-containing Compound Metabolic Process Nuclear Receptor-mediated Signaling Pathway Nuclear Steroid Receptor Activity Chromatin DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Regulation Of Transcription By RNA Polymerase II Steroid Binding Positive Regulation Of Macromolecule Biosynthetic Process Intracellular Signal Transduction Positive Regulation Of Biosynthetic Process Zinc Ion Binding Sequence-specific Double-stranded DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Positive Regulation Of Metabolic Process Positive Regulation Of Macromolecule Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Steroid Hormone Receptor Signaling Pathway Nuclear Receptor-mediated Steroid Hormone Signaling Pathway Chromatin Binding Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Transcription Coregulator Binding Regulation Of Developmental Process Regulation Of Gene Expression Negative Regulation Of RNA Metabolic Process Transcription Coactivator Binding Metal Ion Binding Regulation Of Macromolecule Biosynthetic Process Rhythmic Process Transcription Cis-regulatory Region Binding Nucleus Negative Regulation Of Nucleobase-containing Compound Metabolic Process Cellular Response To Estrogen Stimulus Regulation Of Cell Differentiation Cellular Response To Lipid	Zinc Ion Binding Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Macromolecule Biosynthetic Process Nucleus Regulation Of Macromolecule Metabolic Process Regulation Of Gene Expression Regulation Of DNA-templated Transcription Positive Regulation Of Neuron Projection Arborization Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Biosynthetic Process Regulation Of Neuron Projection Arborization
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