SF1 and TAF15

Number of citations of the paper that reports this interaction (PMID 9660765)
20

Data Source:
HPRD (in vitro)

		SF1	TAF15
Gene Name		splicing factor 1	TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex Ribosome	Nucleus Nucleoplasm Nucleolus Cytoplasm
	Molecular Function	Transcription Corepressor Activity RNA Binding Zinc Ion Binding Poly(A) RNA Binding	Nucleotide Binding DNA Binding Protein Binding Zinc Ion Binding Poly(A) RNA Binding
	Biological Process	Spliceosomal Complex Assembly MRNA 3'-splice Site Recognition MRNA Splicing, Via Spliceosome Transcription, DNA-templated Regulation Of Transcription, DNA-templated Male Sex Determination Leydig Cell Differentiation Negative Regulation Of Smooth Muscle Cell Proliferation Regulation Of Steroid Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription	Positive Regulation Of Transcription, DNA-templated
Pathways
Drugs
Diseases
GWAS		Urate levels ( 21768215)
Protein-Protein Interactions		45 interactors: APBB1 ATXN1 BCAS2 BCL2 CIAO1 DDX17 EFTUD2 ESR1 EWSR1 FAM168A FUS GAS7 HNRNPF HNRNPH1 HNRNPH2 HNRNPK HNRNPUL1 IL7R ILF3 ITCH KRTAP26-1 MKRN3 NFKB1 PLSCR1 PNRC2 PRKG1 PRPF40A PSMA3 RBM10 RBM17 RBM4 RBM7 RBPMS SF3A1 SF3B4 TAF15 TCERG1 TRIM23 TRIM69 U2AF2 WBP4 WDR77 WDR83 WWP2 ZNF461	21 interactors: CACNA1A FUS HIST1H3A HIST2H2AC HIST2H4A HIST3H3 POLR2C POLR2E POLR2G PRMT1 PRMT8 SAFB SF1 TAF1 TAF12 TAF13 TAF5 TAF7 TBP YWHAG ZNF384
Entrez ID		7536	8148
HPRD ID		03306	09031
Ensembl ID		ENSG00000168066	ENSG00000172660
Uniprot IDs		Q15637	Q86X94 Q92804
PDB IDs		1K1G 1OPI 2M09 2M0G 4FXW 4FXX
Enriched GO Terms of Interacting Partners?		RNA Processing RNA Splicing MRNA Processing MRNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Gene Expression RNA Metabolic Process Cellular Aromatic Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Nitrogen Compound Metabolic Process Cellular Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Gene Expression Regulation Of RNA Metabolic Process Regulation Of Metabolic Process Metabolic Process Transcription, DNA-templated Regulation Of RNA Splicing RNA Biosynthetic Process Cellular Process Positive Regulation Of Gene Expression Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Metabolic Process Protein Ubiquitination Cellular Macromolecule Biosynthetic Process Response To Virus Positive Regulation Of Cellular Metabolic Process Protein Modification By Small Protein Conjugation Macromolecule Biosynthetic Process Defense Response To Virus Regulation Of MRNA Splicing, Via Spliceosome Protein Polyubiquitination Regulation Of Viral Genome Replication Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Viral Process Positive Regulation Of Transcription, DNA-templated Regulation Of MRNA Processing Transcription From RNA Polymerase II Promoter Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Cell Activation Apoptotic Process Response To Other Organism	Transcription Initiation From RNA Polymerase II Promoter Transcription Elongation From RNA Polymerase II Promoter DNA-templated Transcription, Initiation DNA-templated Transcription, Elongation Transcription From RNA Polymerase II Promoter Gene Expression Viral Process Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Gene Expression Transcription, DNA-templated Regulation Of Nitrogen Compound Metabolic Process Chromosome Organization Chromatin Organization Cellular Nitrogen Compound Metabolic Process RNA Biosynthetic Process RNA Metabolic Process Chromatin Silencing At RDNA Regulation Of Metabolic Process Negative Regulation Of Gene Expression, Epigenetic Histone Modification MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression 7-methylguanosine MRNA Capping PiRNA Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Chromatin Silencing 7-methylguanosine RNA Capping Transcription-coupled Nucleotide-excision Repair Negative Regulation Of Megakaryocyte Differentiation Cellular Metabolic Process Positive Regulation Of Viral Transcription Regulation Of Transcription, DNA-templated Chromatin Modification Cellular Macromolecule Biosynthetic Process RNA Splicing Regulation Of Nucleic Acid-templated Transcription Macromolecule Biosynthetic Process Peptidyl-arginine Methylation, To Asymmetrical-dimethyl Arginine MRNA Processing Negative Regulation Of Hematopoietic Progenitor Cell Differentiation DNA Replication-dependent Nucleosome Assembly Somatic Stem Cell Maintenance Regulation Of Gene Expression, Epigenetic
Tagcloud ?		aaggtcagaaat aromatase belong br clones coup decided differently dnase ear encode err footprinting hybrid mobility ovary p120e4f promoters s1 shorter silencer situated sk specimen superfamily tf1 variant ws3tf	amyotrophic autosomal carriers coding conserved equivocal et ewsr1 exons export familial frontotemporal fus genotyped genotyping hnrnpa1 hnrnpa2b1 lobar nes neurodegeneration pathogenicity r471c relatives sequenced subject substitution tardbp tdp43 tremor
Tagcloud (Difference) ?		aaggtcagaaat aromatase belong br clones coup decided differently dnase ear encode err footprinting hybrid mobility ovary p120e4f promoters s1 shorter silencer situated sk specimen superfamily tf1 variant ws3tf	amyotrophic autosomal carriers coding conserved equivocal et ewsr1 exons export familial frontotemporal fus genotyped genotyping hnrnpa1 hnrnpa2b1 lobar nes neurodegeneration pathogenicity r471c relatives sequenced subject substitution tardbp tdp43 tremor
Tagcloud (Intersection) ?