ATP5F1A and ATPAF2

Number of citations of the paper that reports this interaction (PubMedID 11410595)
0

Data Source:
HPRD (two hybrid)

		ATP5F1A	ATPAF2
Description		ATP synthase F1 subunit alpha	ATP synthase mitochondrial F1 complex assembly factor 2
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Matrix Plasma Membrane Cell Surface Membrane Proton-transporting Two-sector ATPase Complex Membrane Raft Proton-transporting ATP Synthase Complex Extracellular Exosome Transmembrane Transporter Complex	Mitochondrion Mitochondrial Inner Membrane Cytosol Membrane Nuclear Speck
	Molecular Function	Nucleotide Binding Protease Binding RNA Binding Protein Binding ATP Binding ATP Hydrolysis Activity Adenyl Ribonucleotide Binding MHC Class I Protein Binding ADP Binding Angiostatin Binding Proton-transporting ATP Synthase Activity, Rotational Mechanism	Protein Binding
	Biological Process	Negative Regulation Of Endothelial Cell Proliferation Lipid Metabolic Process ATP Biosynthetic Process Monoatomic Ion Transport Response To Muscle Activity Proton Motive Force-driven ATP Synthesis Proton Motive Force-driven Mitochondrial ATP Synthesis Positive Regulation Of Blood Vessel Endothelial Cell Migration Response To Ethanol ATP Metabolic Process Cellular Response To Dexamethasone Stimulus Cellular Response To Nitric Oxide Proton Transmembrane Transport	Mitochondrial Proton-transporting ATP Synthase Complex Assembly Proton-transporting ATP Synthase Complex Assembly
Pathways		Mitochondrial protein import Formation of ATP by chemiosmotic coupling Cristae formation Mitochondrial protein degradation
Drugs		Quercetin 1-ACETYL-2-CARBOXYPIPERIDINE AUROVERTIN B Piceatannol N1-(2-AMINO-4-METHYLPENTYL)OCTAHYDRO-PYRROLO[1,2-A] PYRIMIDINE Artenimol
Diseases			Mitochondrial respiratory chain deficiencies (MRCD), including: Mitochondrial complex I deficiency (MT-C1D); Complex II deficiency (MT-C2D); Complex III deficiency (MT-C3D); Complex IV deficiency (MT-C4D); Complex V deficiency (MT-ATPSD); Leigh syndrome (LS); Kearns-Sayre Syndrome (KSS); LCHD deficiency (LCHD); Leber Hereditary Optic Neuropathy (LHON); Myoclonic Epilepsy and Ragged-Red Fiber Disease (MERRF); NARP; MELAS; ACAD9 deficiency; HADH deficiency; HIBCH deficiency; GRACILE syndrome
GWAS			Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Schizophrenia ( 25056061 28991256 29483656) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		24 interacting genes: ABCC1 AIMP1 AIRE APP ATP5F1C ATPAF2 CSNK2A1 FNDC3B HSD17B10 HSPB2 LINC00941 LINC01554 NPSR1 OGT PTEN PTPRF SCGN SHBG SMARCB1 TNK2 YWHAB YWHAG YWHAQ YWHAZ	72 interacting genes: AKAP8L APP ATP5F1A ATP5F1B BEGAIN CDC14A CDK2AP1 CEP57 CFAP206 CFAP68 CIMIP2B CRTC2 CTIF CYSRT1 DDIT3 DLGAP4 EBF1 EBF3 EIF4G1 EWSR1 FCHSD2 FNTB GOLGA6L9 IKZF3 INCA1 KRT34 KRT40 KRTAP19-5 KRTAP19-6 KRTAP19-7 KRTAP6-2 KRTAP6-3 LGALS9B LNX1 LRRFIP2 LURAP1L LZTS2 MAGEA6 MEDAG MIF4GD NME4 PAK5 PKP4 POLR2J3 POLR3F POLR3H PPP1R16B PRDM14 PRDM6 RAD54B RBM48 RCN1 REL RPH3AL RPIA SAXO4 SORBS2 SPATC1L TCHP TFIP11 TP53BP2 TRIM23 TRIM27 UBAP2 VWC2 WASHC1 ZFP90 ZNF19 ZNF23 ZNF35 ZNF426 ZNF655
Entrez ID		498	91647
HPRD ID		01258	10599
Ensembl ID		ENSG00000152234	ENSG00000171953
Uniprot IDs		P25705 V9HW26	Q8N5M1
PDB IDs		8H9E 8H9I 8H9L 8H9P 8H9S 8H9T 8H9U 8H9V 8KI3
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Protein Localization To Nucleus Protein Targeting Negative Regulation Of Translational Initiation Phosphoserine Residue Binding Protein Sequestering Activity Identical Protein Binding TORC1 Signaling Regulation Of Translation Protein Domain Specific Binding TOR Signaling Protein Localization To Vacuole Positive Regulation Of Cell Communication Positive Regulation Of Signaling Regulation Of Translational Initiation Sin3-type Complex Regulation Of TORC1 Signaling Post-transcriptional Regulation Of Gene Expression Central Tolerance Induction To Self Antigen Peripheral T Cell Tolerance Induction Positive Regulation Of Transcription By RNA Polymerase II Amyloid-beta Complex Regulation Of Phosphorus Metabolic Process Growth Cone Lamellipodium Positive Regulation Of Protein Metabolic Process Regulation Of Response To Calcium Ion Positive Regulation Of Excitatory Postsynaptic Potential Amylin Binding Positive Regulation Of Toll Signaling Pathway Regulation Of Protein Localization To Nucleus Positive Regulation Of Signal Transduction Reproductive Behavior Isoursodeoxycholate 7-beta-dehydrogenase (NAD+) Activity Chenodeoxycholate 7-alpha-dehydrogenase (NAD+) Activity 3-hydroxy-2-methylbutyryl-CoA Dehydrogenase Activity Cholate 7-alpha-dehydrogenase (NAD+) Activity Ursodeoxycholate 7-beta-dehydrogenase (NAD+) Activity Negative Regulation Of Synaptic Vesicle Clustering Chondroitin Sulfate Proteoglycan Binding Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate Regulation Of TOR Signaling Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Positive Regulation Of Glucagon Secretion Negative Regulation Of Defecation Synapse	Protein Binding Intermediate Filament
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