HTATIP2 and TMEM115

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		HTATIP2	TMEM115
Description		HIV-1 Tat interactive protein 2	transmembrane protein 115
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Cytosol	Golgi Membrane Nucleus Golgi Apparatus Membrane Golgi Transport Complex Golgi Cisterna Membrane
	Molecular Function	Catalytic Activity Protein Serine/threonine Kinase Activity Protein Binding	Protein Binding Identical Protein Binding
	Biological Process	Regulation Of Translation Positive Regulation Of Programmed Cell Death Positive Regulation Of Transcription By RNA Polymerase II Protein Autophosphorylation	Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Negative Regulation Of Cell Population Proliferation Protein Transport
Pathways			COPI-mediated anterograde transport
Drugs		Polyethylene glycol 400
Diseases
GWAS		Bell's palsy ( 33602968) Fractional shortening ( 29403010) Obesity-related traits ( 23251661) Response to inhaled glucocorticoid treatment in asthma (change in FEV1) ( 25601762)	Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Sleep duration (short sleep) ( 30846698) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		29 interacting genes: ABHD4 ACSL4 AQP6 ASF1A CD79A CFTR EHHADH ETS1 FAM209A FITM2 FKBP7 GET1 HDAC6 HSD17B11 JAGN1 JPH1 MIEF1 MTIF3 NCOA5 PITPNC1 PLIN2 RAB5A REEP4 RETREG3 SH3GLB1 SLC10A6 SLC18A1 TMEM115 TMX2	12 interacting genes: AQP6 ASPG CREB3 CYB5R3 HTATIP2 MANBAL RABAC1 SYNE4 TLCD4 TMED8 TMX2 ZDHHC17
Entrez ID		10553	11070
HPRD ID		09288	06144
Ensembl ID		ENSG00000109854	ENSG00000126062
Uniprot IDs		Q9BUP3	A0A024R2Y2 Q12893
PDB IDs		2BKA
Enriched GO Terms of Interacting Partners?		Endoplasmic Reticulum Endoplasmic Reticulum Membrane Lipid Droplet Lipid Biosynthetic Process Lysophosphatidic Acid Acyltransferase Activity Endoplasmic Reticulum Organization Regulation Of Establishment Of Protein Localization Organelle Disassembly Fatty Acid Derivative Metabolic Process Alpha-linolenic Acid Metabolic Process
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