HTATIP2 and PITPNC1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		HTATIP2	PITPNC1
Description		HIV-1 Tat interactive protein 2	phosphatidylinositol transfer protein cytoplasmic 1
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Cytosol	Nucleus Nucleoplasm Cytoplasm Cytosol
	Molecular Function	Catalytic Activity Protein Serine/threonine Kinase Activity Protein Binding	Protein Binding Phospholipid Transporter Activity Lipid Binding Phosphatidylcholine Transporter Activity Phosphatidylinositol Transfer Activity Phosphatidylinositol Binding Phosphatidic Acid Binding Phosphatidylglycerol Binding Phosphatidic Acid Transfer Activity
	Biological Process	Regulation Of Translation Positive Regulation Of Programmed Cell Death Positive Regulation Of Transcription By RNA Polymerase II Protein Autophosphorylation	Lipid Transport Signal Transduction Phospholipid Transport Intermembrane Lipid Transfer
Pathways
Drugs		Polyethylene glycol 400
Diseases
GWAS		Bell's palsy ( 33602968) Fractional shortening ( 29403010) Obesity-related traits ( 23251661) Response to inhaled glucocorticoid treatment in asthma (change in FEV1) ( 25601762)	Blood urea nitrogen levels ( 29403010 31152163) Body size at age 10 ( 32376654) Chronic central serous retinopathy ( 30073298) Chronotype ( 30696823) Diisocyanate-induced asthma ( 25918132) Estimated glomerular filtration rate ( 31152163) Morning person ( 30696823) Plasma selenium concentration ( 33382417) Pulmonary function ( 23932459) Response to protease inhibitor treatment in hepatitis c (peak serum total bilirubin levels) ( 24503447) Serum immune biomarker levels ( 32066700) Type 2 diabetes ( 32499647) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		29 interacting genes: ABHD4 ACSL4 AQP6 ASF1A CD79A CFTR EHHADH ETS1 FAM209A FITM2 FKBP7 GET1 HDAC6 HSD17B11 JAGN1 JPH1 MIEF1 MTIF3 NCOA5 PITPNC1 PLIN2 RAB5A REEP4 RETREG3 SH3GLB1 SLC10A6 SLC18A1 TMEM115 TMX2	14 interacting genes: AGTRAP ANKS6 CACFD1 CMTM5 DGAT2L6 GSG1 HTATIP2 KATNAL1 MAL2 REEP5 SCAMP5 SMPD2 SYP TNFRSF10D
Entrez ID		10553	26207
HPRD ID		09288	05504
Ensembl ID		ENSG00000109854	ENSG00000154217
Uniprot IDs		Q9BUP3	A0A0C4DGP0 Q9UKF7
PDB IDs		2BKA
Enriched GO Terms of Interacting Partners?		Endoplasmic Reticulum Endoplasmic Reticulum Membrane Lipid Droplet Lipid Biosynthetic Process Lysophosphatidic Acid Acyltransferase Activity Endoplasmic Reticulum Organization Regulation Of Establishment Of Protein Localization Organelle Disassembly Fatty Acid Derivative Metabolic Process Alpha-linolenic Acid Metabolic Process
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