VCAM1 and IL13

Number of citations of the paper that reports this interaction (PMID 7521694)
17

Data Source:
HPRD (in vitro)

		VCAM1	IL13
Gene Name		vascular cell adhesion molecule 1	interleukin 13
Image
Gene Ontology Annotations	Cellular Component	Podosome Extracellular Space Early Endosome Endoplasmic Reticulum Golgi Apparatus Plasma Membrane Microvillus External Side Of Plasma Membrane Cell Surface Integral Component Of Membrane Filopodium Sarcolemma Apical Part Of Cell Extracellular Vesicular Exosome Alpha9-beta1 Integrin-vascular Cell Adhesion Molecule-1 Complex	Extracellular Region Extracellular Space Cytoplasm External Side Of Plasma Membrane
	Molecular Function	Integrin Binding Primary Amine Oxidase Activity Cell Adhesion Molecule Binding	Cytokine Activity Interleukin-13 Receptor Binding Protein Binding
	Biological Process	Response To Hypoxia Acute Inflammatory Response Chronic Inflammatory Response Cell Adhesion Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Leukocyte Cell-cell Adhesion Cell-matrix Adhesion Heart Development Aging Response To Nutrient Amine Metabolic Process Response To Zinc Ion Response To Ionizing Radiation Viral Process Cytokine-mediated Signaling Pathway Membrane To Membrane Docking B Cell Differentiation Extracellular Matrix Organization Response To Lipopolysaccharide Response To Nicotine Cellular Response To Vascular Endothelial Growth Factor Stimulus Positive Regulation Of T Cell Proliferation Response To Ethanol Regulation Of Immune Response Leukocyte Tethering Or Rolling Oxidation-reduction Process Cell Chemotaxis Interferon-gamma-mediated Signaling Pathway Chorio-allantoic Fusion Cellular Response To Glucose Stimulus Cellular Response To Tumor Necrosis Factor	Microglial Cell Activation Positive Regulation Of Immunoglobulin Production Movement Of Cell Or Subcellular Component Inflammatory Response Immune Response Signal Transduction Cell-cell Signaling Regulation Of Proton Transport Positive Regulation Of B Cell Proliferation Response To Lipopolysaccharide Positive Regulation Of Connective Tissue Growth Factor Production Negative Regulation Of NAD(P)H Oxidase Activity Response To Nicotine Positive Regulation Of Tyrosine Phosphorylation Of Stat6 Protein Positive Regulation Of Macrophage Activation Response To Ethanol Positive Regulation Of Smooth Muscle Cell Proliferation Positive Regulation Of Protein Secretion Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Cellular Response To Mechanical Stimulus Cellular Response To Cytokine Stimulus Negative Regulation Of Transforming Growth Factor Beta Production Negative Regulation Of Neuron Death Negative Regulation Of Lung Ciliated Cell Differentiation Positive Regulation Of Lung Goblet Cell Differentiation Negative Regulation Of Complement-dependent Cytotoxicity Positive Regulation Of Pancreatic Stellate Cell Proliferation Negative Regulation Of Endothelial Cell Apoptotic Process
Pathways		Interferon gamma signaling Interferon Signaling Cytokine Signaling in Immune system Integrin cell surface interactions Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Adaptive Immune System
Drugs		Carvedilol
Diseases
GWAS		Multiple sclerosis ( 21833088)	Asthma ( 20860503) Atopic dermatitis ( 23042114) Hodgkin's lymphoma ( 22286212) IgE levels ( 22075330) Inflammatory bowel disease ( 23128233) Psoriasis ( 19169254)
Protein-Protein Interactions		10 interactors: CCL17 CCL22 CTSG ELANE EZR IL13 ITGAD ITGB1 ITGB7 MSN	6 interactors: IL13RA1 IL13RA2 IL4 IL4R PIK3R1 VCAM1
Entrez ID		7412	3596
HPRD ID		01888	00981
Ensembl ID		ENSG00000162692	ENSG00000169194
Uniprot IDs		P19320	P35225
PDB IDs		1IJ9 1VCA 1VSC	1GA3 1IJZ 1IK0 1J9U 3BPO 3G6D 3ITR 3ITS 3L5W 3L5X 3L5Y 3LB6 4I77
Enriched GO Terms of Interacting Partners?		Immune System Process Movement Of Cell Or Subcellular Component Response To External Stimulus Heterotypic Cell-cell Adhesion Leukocyte Cell-cell Adhesion Locomotion Response To Other Organism Response To Biotic Stimulus Extracellular Matrix Organization Extracellular Structure Organization Cell Migration Cell Motility Single Organismal Cell-cell Adhesion Membrane To Membrane Docking Leukocyte Migration Killing By Host Of Symbiont Cells Immune Response Regulation Of Immune System Process Defense Response Integrin-mediated Signaling Pathway Leukocyte Tethering Or Rolling Inflammatory Response Neutrophil Mediated Immunity Killing Of Cells Of Other Organism Negative Regulation Of Growth Of Symbiont In Host Defense Response To Fungus Cell Adhesion Establishment Of Endothelial Barrier Cellular Extravasation Chemotaxis Interaction With Symbiont Leukocyte Mediated Cytotoxicity Response To Fungus Viral Entry Into Host Cell Entry Into Host Cell Response To Virus Endothelial Cell Development Response To Lipopolysaccharide Positive Regulation Of Smooth Muscle Cell Proliferation Response To Lipid Response To Molecule Of Bacterial Origin Regulation Of Immune Response Cellular Response To Mechanical Stimulus Positive Regulation Of Connective Tissue Growth Factor Production Positive Regulation Of Lung Goblet Cell Differentiation Negative Regulation Of Lung Ciliated Cell Differentiation Positive Regulation Of Pancreatic Stellate Cell Proliferation Positive Regulation Of Tyrosine Phosphorylation Of Stat6 Protein Endothelial Cell Differentiation Response To Stimulus	Positive Regulation Of Cell Activation Regulation Of Lymphocyte Activation Regulation Of Cell Activation Positive Regulation Of T Cell Activation Positive Regulation Of Homotypic Cell-cell Adhesion Response To Cytokine Positive Regulation Of Cell-cell Adhesion Regulation Of T Cell Activation Positive Regulation Of Immune System Process Regulation Of Cell-cell Adhesion Positive Regulation Of Cell Adhesion B Cell Differentiation Response To Organic Substance Cytokine-mediated Signaling Pathway Positive Regulation Of Lymphocyte Proliferation Negative Regulation Of T-helper Cell Differentiation Positive Regulation Of Mononuclear Cell Proliferation Regulation Of Immune System Process Negative Regulation Of Alpha-beta T Cell Differentiation Cellular Response To Cytokine Stimulus B Cell Activation Cell Surface Receptor Signaling Pathway Regulation Of Cell Adhesion Defense Response To Protozoan Negative Regulation Of Cell Adhesion Negative Regulation Of Alpha-beta T Cell Activation Regulation Of Macrophage Activation Response To Protozoan Cellular Response To Organic Substance Lymphocyte Differentiation Negative Regulation Of Osteoclast Differentiation Regulation Of Immune Response Regulation Of T-helper Cell Differentiation Negative Regulation Of T Cell Differentiation Negative Regulation Of Adaptive Immune Response Regulation Of CD4-positive, Alpha-beta T Cell Differentiation Positive Regulation Of Immunoglobulin Production Positive Regulation Of B Cell Proliferation Positive Regulation Of Chemokine Production Leukocyte Differentiation Negative Regulation Of Lymphocyte Differentiation Negative Regulation Of Myeloid Leukocyte Differentiation Positive Regulation Of Cytokine Production Negative Regulation Of Immune System Process Regulation Of Chemokine Production Regulation Of B Cell Proliferation Lymphocyte Activation Regulation Of Osteoclast Differentiation Immune Response Signal Transduction
Tagcloud ?		accessory cd4 delayed determinant dr foreign genital hpvs hypersensitivity icam1 immuno keratinocytes langerhans lymphocytes monitored mount nonregressing papillomavirus predominated rank regressing regression responsiveness selectin stroma sum wart warts wilcoxon	30min ancestry asks asleep habitual ifng ifngr1 il10 il17a il1b il1r2 il2 il4 il6 il8 interleukins nfkb1 nfkb2 pittsburgh rs1143623 rs1143642 rs1295686 rs2857602 rs4648110 rs4719714 soi strengthens tnfa transgender
Tagcloud (Difference) ?		accessory cd4 delayed determinant dr foreign genital hpvs hypersensitivity icam1 immuno keratinocytes langerhans lymphocytes monitored mount nonregressing papillomavirus predominated rank regressing regression responsiveness selectin stroma sum wart warts wilcoxon	30min ancestry asks asleep habitual ifng ifngr1 il10 il17a il1b il1r2 il2 il4 il6 il8 interleukins nfkb1 nfkb2 pittsburgh rs1143623 rs1143642 rs1295686 rs2857602 rs4648110 rs4719714 soi strengthens tnfa transgender
Tagcloud (Intersection) ?