VCAM1 and ITGB7

Number of citations of the paper that reports this interaction (PMID 12682249)
8

Data Source:
HPRD (in vitro)

		VCAM1	ITGB7
Gene Name		vascular cell adhesion molecule 1	integrin, beta 7
Image
Gene Ontology Annotations	Cellular Component	Podosome Extracellular Space Early Endosome Endoplasmic Reticulum Golgi Apparatus Plasma Membrane Microvillus External Side Of Plasma Membrane Cell Surface Integral Component Of Membrane Filopodium Sarcolemma Apical Part Of Cell Extracellular Vesicular Exosome Alpha9-beta1 Integrin-vascular Cell Adhesion Molecule-1 Complex	Plasma Membrane Integrin Complex Cell Surface Membrane Integrin Alpha4-beta7 Complex Receptor Complex Extracellular Vesicular Exosome
	Molecular Function	Integrin Binding Primary Amine Oxidase Activity Cell Adhesion Molecule Binding	Virus Receptor Activity Protein Binding Metal Ion Binding Cell Adhesion Molecule Binding
	Biological Process	Response To Hypoxia Acute Inflammatory Response Chronic Inflammatory Response Cell Adhesion Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Leukocyte Cell-cell Adhesion Cell-matrix Adhesion Heart Development Aging Response To Nutrient Amine Metabolic Process Response To Zinc Ion Response To Ionizing Radiation Viral Process Cytokine-mediated Signaling Pathway Membrane To Membrane Docking B Cell Differentiation Extracellular Matrix Organization Response To Lipopolysaccharide Response To Nicotine Cellular Response To Vascular Endothelial Growth Factor Stimulus Positive Regulation Of T Cell Proliferation Response To Ethanol Regulation Of Immune Response Leukocyte Tethering Or Rolling Oxidation-reduction Process Cell Chemotaxis Interferon-gamma-mediated Signaling Pathway Chorio-allantoic Fusion Cellular Response To Glucose Stimulus Cellular Response To Tumor Necrosis Factor	Cell-matrix Adhesion Involved In Ameboidal Cell Migration Cell Adhesion Cell-matrix Adhesion Integrin-mediated Signaling Pathway Multicellular Organismal Development Response To Virus Extracellular Matrix Organization Heterotypic Cell-cell Adhesion Substrate Adhesion-dependent Cell Spreading Receptor Clustering Regulation Of Immune Response Leukocyte Tethering Or Rolling T Cell Migration
Pathways		Interferon gamma signaling Interferon Signaling Cytokine Signaling in Immune system Integrin cell surface interactions Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Adaptive Immune System	Integrin cell surface interactions Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Adaptive Immune System
Drugs		Carvedilol
Diseases
GWAS		Multiple sclerosis ( 21833088)	Obesity-related traits ( 23251661)
Protein-Protein Interactions		10 interactors: CCL17 CCL22 CTSG ELANE EZR IL13 ITGAD ITGB1 ITGB7 MSN	15 interactors: CDH1 DAB1 DOK1 EED FLNA FN1 GNB2L1 ITGA4 ITGAE MADCAM1 PRKCB PRKCD TLN1 TNS2 VCAM1
Entrez ID		7412	3695
HPRD ID		01888	00948
Ensembl ID		ENSG00000162692	ENSG00000139626
Uniprot IDs		P19320	P26010
PDB IDs		1IJ9 1VCA 1VSC	2BRQ 3V4P 3V4V
Enriched GO Terms of Interacting Partners?		Immune System Process Movement Of Cell Or Subcellular Component Response To External Stimulus Heterotypic Cell-cell Adhesion Leukocyte Cell-cell Adhesion Locomotion Response To Other Organism Response To Biotic Stimulus Extracellular Matrix Organization Extracellular Structure Organization Cell Migration Cell Motility Single Organismal Cell-cell Adhesion Membrane To Membrane Docking Leukocyte Migration Killing By Host Of Symbiont Cells Immune Response Regulation Of Immune System Process Defense Response Integrin-mediated Signaling Pathway Leukocyte Tethering Or Rolling Inflammatory Response Neutrophil Mediated Immunity Killing Of Cells Of Other Organism Negative Regulation Of Growth Of Symbiont In Host Defense Response To Fungus Cell Adhesion Establishment Of Endothelial Barrier Cellular Extravasation Chemotaxis Interaction With Symbiont Leukocyte Mediated Cytotoxicity Response To Fungus Viral Entry Into Host Cell Entry Into Host Cell Response To Virus Endothelial Cell Development Response To Lipopolysaccharide Positive Regulation Of Smooth Muscle Cell Proliferation Response To Lipid Response To Molecule Of Bacterial Origin Regulation Of Immune Response Cellular Response To Mechanical Stimulus Positive Regulation Of Connective Tissue Growth Factor Production Positive Regulation Of Lung Goblet Cell Differentiation Negative Regulation Of Lung Ciliated Cell Differentiation Positive Regulation Of Pancreatic Stellate Cell Proliferation Positive Regulation Of Tyrosine Phosphorylation Of Stat6 Protein Endothelial Cell Differentiation Response To Stimulus	Cell Adhesion Regulation Of Body Fluid Levels Extracellular Matrix Organization Extracellular Structure Organization Leukocyte Tethering Or Rolling Cell Activation Platelet Activation Blood Coagulation Hemostasis Single Organismal Cell-cell Adhesion Cellular Extravasation Wound Healing Positive Regulation Of Cellular Protein Metabolic Process B Cell Activation Response To Wounding Cell-matrix Adhesion Positive Regulation Of Protein Metabolic Process Receptor Clustering Cell Junction Assembly Cell-substrate Adhesion Regulation Of Immune Response Leukocyte Migration Positive Regulation Of Protein Modification Process Platelet Degranulation Cell-cell Adhesion Via Plasma-membrane Adhesion Molecules Cell-cell Adhesion Chorio-allantoic Fusion Regulation Of Protein Metabolic Process Signal Transduction Regulation Of Cellular Process Anatomical Structure Morphogenesis Cellular Response To Stimulus Response To Stimulus Developmental Process Cell Differentiation Cell Morphogenesis Involved In Differentiation Integrin-mediated Signaling Pathway Protein Localization To Membrane Signaling Locomotion Cell Communication Regulation Of Immune System Process Regulation Of Cellular Protein Metabolic Process Labyrinthine Layer Morphogenesis Heterotypic Cell-cell Adhesion Lymphocyte Activation Multicellular Organismal Development Cell Migration Membrane Organization Embryonic Placenta Morphogenesis
Tagcloud ?		accessory cd4 delayed determinant dr foreign genital hpvs hypersensitivity icam1 immuno keratinocytes langerhans lymphocytes monitored mount nonregressing papillomavirus predominated rank regressing regression responsiveness selectin stroma sum wart warts wilcoxon
Tagcloud (Difference) ?		accessory cd4 delayed determinant dr foreign genital hpvs hypersensitivity icam1 immuno keratinocytes langerhans lymphocytes monitored mount nonregressing papillomavirus predominated rank regressing regression responsiveness selectin stroma sum wart warts wilcoxon
Tagcloud (Intersection) ?