IL13

Gene Name		interleukin 13
Image
Gene Ontology Annotations	Cellular Component	Extracellular Region Extracellular Space Cytoplasm External Side Of Plasma Membrane
	Molecular Function	Cytokine Activity Interleukin-13 Receptor Binding Protein Binding
	Biological Process	Microglial Cell Activation Positive Regulation Of Immunoglobulin Production Movement Of Cell Or Subcellular Component Inflammatory Response Immune Response Signal Transduction Cell-cell Signaling Regulation Of Proton Transport Positive Regulation Of B Cell Proliferation Response To Lipopolysaccharide Positive Regulation Of Connective Tissue Growth Factor Production Negative Regulation Of NAD(P)H Oxidase Activity Response To Nicotine Positive Regulation Of Tyrosine Phosphorylation Of Stat6 Protein Positive Regulation Of Macrophage Activation Response To Ethanol Positive Regulation Of Smooth Muscle Cell Proliferation Positive Regulation Of Protein Secretion Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Cellular Response To Mechanical Stimulus Cellular Response To Cytokine Stimulus Negative Regulation Of Transforming Growth Factor Beta Production Negative Regulation Of Neuron Death Negative Regulation Of Lung Ciliated Cell Differentiation Positive Regulation Of Lung Goblet Cell Differentiation Negative Regulation Of Complement-dependent Cytotoxicity Positive Regulation Of Pancreatic Stellate Cell Proliferation Negative Regulation Of Endothelial Cell Apoptotic Process
Pathways
Drugs
Diseases
GWAS		Asthma ( 20860503) Atopic dermatitis ( 23042114) Hodgkin's lymphoma ( 22286212) IgE levels ( 22075330) Inflammatory bowel disease ( 23128233) Psoriasis ( 19169254)
Protein-protein Interactions		6 interactors: IL13RA1 IL13RA2 IL4 IL4R PIK3R1 VCAM1
Entrez ID		3596
HPRD ID		00981
Ensembl ID		ENSG00000169194
Uniprot IDs		P35225
PDB IDs		1GA3 1IJZ 1IK0 1J9U 3BPO 3G6D 3ITR 3ITS 3L5W 3L5X 3L5Y 3LB6 4I77
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Cell Activation Regulation Of Lymphocyte Activation Regulation Of Cell Activation Positive Regulation Of T Cell Activation Positive Regulation Of Homotypic Cell-cell Adhesion Response To Cytokine Positive Regulation Of Cell-cell Adhesion Regulation Of T Cell Activation Positive Regulation Of Immune System Process Regulation Of Cell-cell Adhesion Positive Regulation Of Cell Adhesion B Cell Differentiation Response To Organic Substance Cytokine-mediated Signaling Pathway Positive Regulation Of Lymphocyte Proliferation Negative Regulation Of T-helper Cell Differentiation Positive Regulation Of Mononuclear Cell Proliferation Regulation Of Immune System Process Negative Regulation Of Alpha-beta T Cell Differentiation Cellular Response To Cytokine Stimulus B Cell Activation Cell Surface Receptor Signaling Pathway Regulation Of Cell Adhesion Defense Response To Protozoan Negative Regulation Of Cell Adhesion Negative Regulation Of Alpha-beta T Cell Activation Regulation Of Macrophage Activation Response To Protozoan Cellular Response To Organic Substance Lymphocyte Differentiation Negative Regulation Of Osteoclast Differentiation Regulation Of Immune Response Regulation Of T-helper Cell Differentiation Negative Regulation Of T Cell Differentiation Negative Regulation Of Adaptive Immune Response Regulation Of CD4-positive, Alpha-beta T Cell Differentiation Positive Regulation Of Immunoglobulin Production Positive Regulation Of B Cell Proliferation Positive Regulation Of Chemokine Production Leukocyte Differentiation Negative Regulation Of Lymphocyte Differentiation Negative Regulation Of Myeloid Leukocyte Differentiation Positive Regulation Of Cytokine Production Negative Regulation Of Immune System Process Regulation Of Chemokine Production Regulation Of B Cell Proliferation Lymphocyte Activation Regulation Of Osteoclast Differentiation Immune Response Signal Transduction
Tagcloud ?		30min ancestry asks asleep habitual ifng ifngr1 il10 il17a il1b il1r2 il2 il4 il6 il8 interleukins nfkb1 nfkb2 pittsburgh rs1143623 rs1143642 rs1295686 rs2857602 rs4648110 rs4719714 soi strengthens tnfa transgender