UPP1 and CTDP1

Number of citations of the paper that reports this interaction (PMID 12036313)
6

Data Source:
BioGRID (enzymatic study)

		UPP1	CTDP1
Gene Name		uridine phosphorylase 1	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
Image
Gene Ontology Annotations	Cellular Component	Cytosol	Spindle Pole Nucleoplasm Cytoplasm Centrosome Spindle Actin Cytoskeleton Midbody Spindle Midzone
	Molecular Function	Uridine Phosphorylase Activity	DNA-directed RNA Polymerase Activity CTD Phosphatase Activity
	Biological Process	Nucleobase-containing Compound Metabolic Process Pyrimidine Nucleobase Metabolic Process Nucleotide Catabolic Process Cellular Response To Glucose Starvation Pyrimidine Nucleoside Salvage UMP Salvage Small Molecule Metabolic Process Uridine Metabolic Process Pyrimidine Nucleoside Catabolic Process Nucleobase-containing Small Molecule Metabolic Process	Transcription From RNA Polymerase II Promoter Transcription Elongation From RNA Polymerase II Promoter Protein Dephosphorylation Exit From Mitosis Gene Expression Viral Process Positive Regulation Of Viral Transcription Cell Division
Pathways		Pyrimidine catabolism Pyrimidine salvage reactions Pyrimidine metabolism Metabolism of nucleotides	Formation of HIV-1 elongation complex containing HIV-1 Tat RNA Polymerase II Transcription Abortive elongation of HIV-1 transcript in the absence of Tat HIV Infection Formation of the Early Elongation Complex Tat-mediated elongation of the HIV-1 transcript Tat-mediated HIV elongation arrest and recovery RNA Polymerase II Pre-transcription Events Late Phase of HIV Life Cycle Pausing and recovery of Tat-mediated HIV elongation Formation of RNA Pol II elongation complex HIV elongation arrest and recovery HIV Life Cycle Pausing and recovery of HIV elongation Formation of HIV elongation complex in the absence of HIV Tat Formation of the HIV-1 Early Elongation Complex HIV Transcription Elongation Transcription of the HIV genome RNA Polymerase II Transcription Elongation
Drugs
Diseases
GWAS			Schizophrenia ( 23212062)
Protein-Protein Interactions		2 interactors: CTDP1 VIM	42 interactors: CDK7 CDK8 CDK9 CSNK2A1 CSNK2A2 CSNK2B E2F1 ELP2 ELP3 ERH GTF2F1 HIST1H4A HIST2H2AC INTS1 INTS3 INTS6 INTS7 INTS8 MED1 MED14 MED15 MED16 MED17 MED23 MED24 MED25 MED26 MED4 MED6 MED7 MED8 NDRG2 POLR2A POLR2B PRKDC PRMT5 SNRNP70 SNRPB STK38 TCEA1 UPP1 WDR77
Entrez ID		7378	9150
HPRD ID		08932	05377
Ensembl ID		ENSG00000183696	ENSG00000060069
Uniprot IDs		B4DND0 Q16831 Q86Y75	Q9Y5B0
PDB IDs		3EUE 3EUF 3NBQ	1J2X 1ONV 2K7L
Enriched GO Terms of Interacting Partners?		Viral Process Bergmann Glial Cell Differentiation Exit From Mitosis Intermediate Filament Organization Lens Fiber Cell Development Astrocyte Development Muscle Filament Sliding Actin-myosin Filament Sliding Lens Fiber Cell Differentiation Intermediate Filament Cytoskeleton Organization Astrocyte Differentiation Intermediate Filament-based Process Actin-mediated Cell Contraction Positive Regulation Of Viral Transcription Positive Regulation Of Gene Expression SMAD Protein Signal Transduction Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Transcription Elongation From RNA Polymerase II Promoter Actin Filament-based Movement Regulation Of Viral Transcription Positive Regulation Of Viral Process Execution Phase Of Apoptosis DNA-templated Transcription, Elongation Lens Development In Camera-type Eye Glial Cell Development Negative Regulation Of Neuron Projection Development	Transcription Initiation From RNA Polymerase II Promoter DNA-templated Transcription, Initiation Nucleobase-containing Compound Metabolic Process RNA Metabolic Process Transcription From RNA Polymerase II Promoter Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Transcription, DNA-templated Gene Expression RNA Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of RNA Metabolic Process Transcription Elongation From RNA Polymerase II Promoter Cellular Metabolic Process Cellular Macromolecule Biosynthetic Process Androgen Receptor Signaling Pathway Regulation Of RNA Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Gene Expression DNA-templated Transcription, Elongation Regulation Of Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Positive Regulation Of Gene Expression Regulation Of Metabolic Process Intracellular Steroid Hormone Receptor Signaling Pathway Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Viral Transcription NcRNA Metabolic Process Positive Regulation Of Cellular Biosynthetic Process SnRNA Processing Regulation Of Viral Transcription Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Viral Process Stem Cell Maintenance SnRNA Metabolic Process Positive Regulation Of Cellular Metabolic Process Metabolic Process Intracellular Receptor Signaling Pathway Positive Regulation Of Transcription From RNA Polymerase II Promoter Cell Cycle Checkpoint MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Stem Cell Development Positive Regulation Of Metabolic Process 7-methylguanosine MRNA Capping Regulation Of Viral Process
Tagcloud ?			13q14 18qtel 1p32 3p14 3q21 4q11 4q24 5p13 5p15 5ptel 8p23 9qtel c84c11 cgh d1s427 d5s23 d8s504 d9s325 dab2 dxs7132 faf1 fhit genosensor imbalances q12 rbp1 rbp2 shgc xq12
Tagcloud (Difference) ?			13q14 18qtel 1p32 3p14 3q21 4q11 4q24 5p13 5p15 5ptel 8p23 9qtel c84c11 cgh d1s427 d5s23 d8s504 d9s325 dab2 dxs7132 faf1 fhit genosensor imbalances q12 rbp1 rbp2 shgc xq12
Tagcloud (Intersection) ?