UPP1

Description		uridine phosphorylase 1
Image
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol
	Molecular Function	Catalytic Activity Uridine Phosphorylase Activity Thymidine Phosphorylase Activity Transferase Activity Glycosyltransferase Activity Pentosyltransferase Activity Identical Protein Binding Deoxyuridine Phosphorylase Activity
	Biological Process	Nucleobase-containing Compound Metabolic Process Uridine Catabolic Process Pyrimidine Nucleotide Metabolic Process CMP Catabolic Process DCMP Catabolic Process Nucleoside Metabolic Process Nucleotide Catabolic Process Cellular Response To Glucose Starvation UMP Salvage UMP Catabolic Process DTMP Catabolic Process DUMP Catabolic Process Uridine Metabolic Process
Pathways		Pyrimidine salvage Pyrimidine catabolism
Drugs		5-Benzylacyclouridine
Diseases
GWAS		Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Metabolite levels ( 23823483)
Interacting Genes		3 interacting genes: CRYAA CTDP1 VIM
Entrez ID		7378
HPRD ID		08932
Ensembl ID		ENSG00000183696
Uniprot IDs		B4DND0 Q16831 Q86Y75
PDB IDs		3EUE 3EUF 3NBQ
Enriched GO Terms of Interacting Partners?		Structural Constituent Of Eye Lens Regulation Of Cell Growth Regulation Of Cellular Component Organization Tubulin Complex Assembly Response To UV-A Regulation Of Growth Lens Fiber Cell Morphogenesis Embryonic Eye Morphogenesis Apoptotic Process Involved In Morphogenesis Embryonic Camera-type Eye Morphogenesis Lens Morphogenesis In Camera-type Eye Supramolecular Fiber Organization Lens Fiber Cell Development Astrocyte Development Keratin Filament Binding Cellular Response To Muramyl Dipeptide Bergmann Glial Cell Differentiation Response To Muramyl Dipeptide Positive Regulation Of Collagen Biosynthetic Process Tat Protein Binding TFIIF-class Transcription Factor Complex Binding Host-mediated Activation Of Viral Transcription Regulation Of Cell Growth Involved In Cardiac Muscle Cell Development Negative Regulation Of Cell Growth Involved In Cardiac Muscle Cell Development Negative Regulation Of Cardiac Muscle Tissue Growth RNA Polymerase II CTD Heptapeptide Repeat Phosphatase Activity Spindle Midzone Exit From Mitosis Protein Refolding Host-mediated Perturbation Of Viral Transcription Apoptotic Process Involved In Development Protein-containing Complex Astrocyte Differentiation Negative Regulation Of Organ Growth Regulation Of Collagen Biosynthetic Process Negative Regulation Of Muscle Hypertrophy Host-mediated Activation Of Viral Process Negative Regulation Of Cardiac Muscle Hypertrophy Lens Development In Camera-type Eye Regulation Of Collagen Metabolic Process Negative Regulation Of Striated Muscle Cell Differentiation
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