PPHLN1 and SEPTIN8

Number of citations of the paper that reports this interaction (PubMedID 21900206)
0

Data Source:
BioGRID (two hybrid)

		PPHLN1	SEPTIN8
Description		periphilin 1	septin 8
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Chromosome Cytoplasm Golgi Apparatus Cytosol	Cytoplasm Cytoskeleton Septin Ring Microtubule Cytoskeleton Membrane Axon Synaptic Vesicle Membrane Septin Complex Cytoplasmic Vesicle Cell Division Site Cell Projection Synapse Presynapse
	Molecular Function	RNA Binding Protein Binding	Nucleotide Binding GTPase Activity Protein Binding GTP Binding Molecular Adaptor Activity
	Biological Process	Keratinization Negative Regulation Of Gene Expression, Epigenetic Negative Regulation Of DNA-templated Transcription Protein Localization To Heterochromatin Constitutive Heterochromatin Formation	Intracellular Protein Localization Regulation Of Protein Stability Regulation Of Intracellular Protein Transport Regulation Of SNARE Complex Assembly Cytoskeleton-dependent Cytokinesis
Pathways		Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex
Drugs
Diseases
GWAS		Body size at age 10 ( 32376654) Coronary artery disease ( 29212778) Diastolic blood pressure ( 30224653) Refractive error ( 32231278)
Interacting Genes		27 interacting genes: APP BCL2L1 CASP5 CCDC57 CDC37 CDK6 CLK1 FBXO7 FXR1 ITGB1BP2 MTUS2 NAGK OGT PAXIP1 PPL SEPTIN8 SHANK3 SNCAIP SQSTM1 SRPK2 TGM2 TOMM20 TOPBP1 TP53BP2 TSGA10 UFD1 VIM	11 interacting genes: A2M CDK14 ESR1 JADE1 KMT2B PPHLN1 SEPTIN4 SEPTIN5 SH3GL1 SH3GL3 SPTBN1
Entrez ID		51535	23176
HPRD ID		10488	12228
Ensembl ID		ENSG00000134283	ENSG00000164402
Uniprot IDs		F8W6A0 Q8NEY8	A6NFQ9 B7ZVZ1 Q92599
PDB IDs		6SWG	6UPR 6WSM
Enriched GO Terms of Interacting Partners?		Regulation Of Long-term Synaptic Potentiation Regulation Of Long-term Neuronal Synaptic Plasticity Positive Regulation Of Long-term Synaptic Potentiation Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Cytoplasm Regulation Of Cell Cycle Regulation Of Neuron Apoptotic Process Intracellular Membraneless Organelle Cell Death Positive Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of Neuronal Synaptic Plasticity Neuron Projection Positive Regulation Of Neuron Apoptotic Process Negative Regulation Of Long-term Synaptic Potentiation Cytosol Glial Cell Development Scaffold Protein Binding Autophagy Of Mitochondrion Regulation Of Defense Response Intracellular Signal Transduction Regulation Of Synaptic Plasticity Regulation Of Programmed Cell Death Cytoskeleton Protein Targeting Apoptotic Process Cellular Response To Catecholamine Stimulus Astrocyte Development Presynapse Programmed Cell Death Response To Catecholamine Synapse Response To Muramyl Dipeptide Regulation Of Innate Immune Response Positive Regulation Of Mitophagy SH3 Domain Binding Amyloid-beta Complex Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Growth Cone Lamellipodium Modulation Of Chemical Synaptic Transmission Regulation Of Response To Calcium Ion Positive Regulation Of Excitatory Postsynaptic Potential Amylin Binding Positive Regulation Of Toll Signaling Pathway Regulation Of Apoptotic Process Positive Regulation Of Synaptic Transmission Protein Binding Developmental Process Regulation Of Mitotic Cell Cycle Organelle Organization	Cytoskeleton-dependent Cytokinesis Cell Division Site Septin Ring Septin Complex Central Nervous System Development Presynapse Protein Localization To Chromatin
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