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PPHLN1 and CASP5
Number of citations of the paper that reports this interaction (PMID
12853457
)
5
Data Source:
HPRD
(in vitro)
PPHLN1
CASP5
Gene Name
periphilin 1
caspase 5, apoptosis-related cysteine peptidase
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleoplasm
Cytoplasm
Golgi Apparatus
Intracellular Membrane-bounded Organelle
Cytoplasm
Neuron Projection
Neuronal Cell Body
IPAF Inflammasome Complex
NLRP1 Inflammasome Complex
NLRP3 Inflammasome Complex
AIM2 Inflammasome Complex
Molecular Function
Poly(A) RNA Binding
Cysteine-type Endopeptidase Activity
Cysteine-type Peptidase Activity
Scaffold Protein Binding
Biological Process
Keratinization
Proteolysis
Apoptotic Process
Substantia Nigra Development
Ectopic Germ Cell Programmed Cell Death
Regulation Of Apoptotic Process
Positive Regulation Of Interleukin-1 Beta Secretion
Regulation Of Inflammatory Response
Pyroptosis
Cellular Response To Mechanical Stimulus
Execution Phase Of Apoptosis
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions
20 interactors:
APP
BCL2L1
BRCA1
CASP5
CCDC57
CDC37
CDK6
MTUS2
NAGK
PAXIP1
PPL
SEPT8
SNCAIP
SQSTM1
TGM2
TOMM20
TP53BP2
TSGA10
UFD1L
VIM
3 interactors:
MAX
NLRP1
PPHLN1
Entrez ID
51535
838
HPRD ID
10488
04048
Ensembl ID
ENSG00000134283
ENSG00000137757
Uniprot IDs
B7Z8L1
E9PAX8
F8W6A0
Q8NEY8
P51878
PDB IDs
Enriched GO Terms of Interacting Partners
?
Response To Ionizing Radiation
Apoptotic Process
Programmed Cell Death
Cell Death
Death
Response To Radiation
Positive Regulation Of Histone H3-K4 Methylation
Regulation Of Cell Cycle
Positive Regulation Of Histone Acetylation
Signal Transduction By P53 Class Mediator
Developmental Process
Regulation Of Histone H3-K4 Methylation
Response To Abiotic Stimulus
Positive Regulation Of Peptidyl-lysine Acetylation
Apoptotic Signaling Pathway
Organ Development
Positive Regulation Of Protein Acetylation
Astrocyte Development
Multicellular Organismal Development
Anatomical Structure Development
System Development
Endoplasmic Reticulum Calcium Ion Homeostasis
Negative Regulation Of Cell Cycle
Positive Regulation Of Histone Methylation
Intrinsic Apoptotic Signaling Pathway
Intracellular Receptor Signaling Pathway
Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway
Astrocyte Differentiation
Regulation Of Histone Acetylation
Central Nervous System Development
Positive Regulation Of Gene Expression
Regulation Of Histone Methylation
Neuron Apoptotic Process
Positive Regulation Of Histone H4-K20 Methylation
Cell Dedifferentiation
Positive Regulation Of Histone H3-K36 Methylation
Positive Regulation Of Histone H4-K16 Acetylation
Apoptotic Process In Bone Marrow
Regulation Of Signaling
Neuron Death
Positive Regulation Of Histone Modification
Execution Phase Of Apoptosis
Isopeptide Cross-linking Via N6-(L-isoglutamyl)-L-lysine
Synaptic Growth At Neuromuscular Junction
Positive Regulation Of Histone H3-K9 Acetylation
N-acetylmannosamine Metabolic Process
DNA Damage Response, Signal Transduction By P53 Class Mediator
Cell Differentiation
Cellular Protein Metabolic Process
Signal Transduction In Response To DNA Damage
Neuron Apoptotic Process
Neuron Death
Response To Peptide
Tagcloud
?
11q
18q21
18q22
3p
aplp1
carcinoids
casp1
casp4
chromosomes
clustered
dad1
gains
gpr112
hierarchical
il12a
ileal
mir133a
or51e1
paid
prkca
profiling
q21
q22
q23
ret
runx1
rybp
spock1
vmat1
Tagcloud (Difference)
?
11q
18q21
18q22
3p
aplp1
carcinoids
casp1
casp4
chromosomes
clustered
dad1
gains
gpr112
hierarchical
il12a
ileal
mir133a
or51e1
paid
prkca
profiling
q21
q22
q23
ret
runx1
rybp
spock1
vmat1
Tagcloud (Intersection)
?