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PPHLN1 and CDC37
Number of citations of the paper that reports this interaction (PMID
21900206
)
27
Data Source:
BioGRID
(two hybrid)
PPHLN1
CDC37
Gene Name
periphilin 1
cell division cycle 37
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleoplasm
Cytoplasm
Golgi Apparatus
Intracellular Membrane-bounded Organelle
Cytoplasm
Cytosol
Ruffle Membrane
Protein Complex
Extracellular Vesicular Exosome
Molecular Function
Poly(A) RNA Binding
Protein Binding
Kinase Binding
Heat Shock Protein Binding
Mitogen-activated Protein Kinase Kinase Kinase Binding
Protein Kinase B Binding
Unfolded Protein Binding
Chaperone Binding
Hsp90 Protein Binding
Biological Process
Keratinization
Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
Protein Folding
Protein Targeting
Protein Stabilization
Regulation Of Interferon-gamma-mediated Signaling Pathway
Regulation Of Type I Interferon-mediated Signaling Pathway
Pathways
Signaling by ERBB2
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants
Signaling by EGFR in Cancer
Signaling by Ligand-Responsive EGFR Variants in Cancer
Signaling by EGFRvIII in Cancer
Constitutive Signaling by EGFRvIII
Drugs
Diseases
GWAS
Multiple sclerosis (
21833088
)
Protein-Protein Interactions
20 interactors:
APP
BCL2L1
BRCA1
CASP5
CCDC57
CDC37
CDK6
MTUS2
NAGK
PAXIP1
PPL
SEPT8
SNCAIP
SQSTM1
TGM2
TOMM20
TP53BP2
TSGA10
UFD1L
VIM
72 interactors:
A2M
APOE
APP
AR
BTBD10
C19orf44
CC2D1A
CDC37L1
CDK2
CDK3
CDK4
CDK5
CDK6
CDK7
CHGA
CHUK
CKS1B
CKS2
CRYM
CSNK2A1
CSNK2A2
CYP2C9
DCTN1
DEAF1
ECSIT
EIF2AK1
ELAVL3
EXOSC1
FBXL12
FBXW4
GCDH
GCH1
HSP90AA1
IFIT3
IFIT5
IKBKB
IKBKE
IKBKG
IMMT
LONP1
LOXL4
LUC7L2
MAP3K14
MAP3K3
MGEA5
MTOR
MZT2B
NCOA5
NOS3
NR2C2
PPHLN1
PRAM1
PRDX2
PRMT1
PSME1
RAD23A
RNF32
RPS15A
SAFB
SNX5
SPTBN4
SQSTM1
SRC
STAMBPL1
STIP1
STK11
TBK1
UBE2I
ZNF205
ZNF235
ZNF266
ZNF667
Entrez ID
51535
11140
HPRD ID
10488
05456
Ensembl ID
ENSG00000134283
ENSG00000105401
Uniprot IDs
B7Z8L1
E9PAX8
F8W6A0
Q8NEY8
Q16543
PDB IDs
1US7
2K5B
2W0G
Enriched GO Terms of Interacting Partners
?
Response To Ionizing Radiation
Apoptotic Process
Programmed Cell Death
Cell Death
Death
Response To Radiation
Positive Regulation Of Histone H3-K4 Methylation
Regulation Of Cell Cycle
Positive Regulation Of Histone Acetylation
Signal Transduction By P53 Class Mediator
Developmental Process
Regulation Of Histone H3-K4 Methylation
Response To Abiotic Stimulus
Positive Regulation Of Peptidyl-lysine Acetylation
Apoptotic Signaling Pathway
Organ Development
Positive Regulation Of Protein Acetylation
Astrocyte Development
Multicellular Organismal Development
Anatomical Structure Development
System Development
Endoplasmic Reticulum Calcium Ion Homeostasis
Negative Regulation Of Cell Cycle
Positive Regulation Of Histone Methylation
Intrinsic Apoptotic Signaling Pathway
Intracellular Receptor Signaling Pathway
Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway
Astrocyte Differentiation
Regulation Of Histone Acetylation
Central Nervous System Development
Positive Regulation Of Gene Expression
Regulation Of Histone Methylation
Neuron Apoptotic Process
Positive Regulation Of Histone H4-K20 Methylation
Cell Dedifferentiation
Positive Regulation Of Histone H3-K36 Methylation
Positive Regulation Of Histone H4-K16 Acetylation
Apoptotic Process In Bone Marrow
Regulation Of Signaling
Neuron Death
Positive Regulation Of Histone Modification
Execution Phase Of Apoptosis
Isopeptide Cross-linking Via N6-(L-isoglutamyl)-L-lysine
Synaptic Growth At Neuromuscular Junction
Positive Regulation Of Histone H3-K9 Acetylation
N-acetylmannosamine Metabolic Process
DNA Damage Response, Signal Transduction By P53 Class Mediator
Cell Differentiation
Cellular Protein Metabolic Process
Signal Transduction In Response To DNA Damage
Regulation Of Cellular Protein Metabolic Process
Regulation Of Metabolic Process
Regulation Of Protein Metabolic Process
Protein Phosphorylation
Regulation Of Phosphorylation
Regulation Of Phosphorus Metabolic Process
Positive Regulation Of Cellular Metabolic Process
Positive Regulation Of Metabolic Process
Regulation Of Protein Phosphorylation
Response To Stress
Cellular Metabolic Process
Response To External Stimulus
Phosphorylation
Regulation Of Nitrogen Compound Metabolic Process
Regulation Of Cell Cycle
Positive Regulation Of Cellular Biosynthetic Process
Regulation Of Protein Kinase Activity
I-kappaB Kinase/NF-kappaB Signaling
Response To Stimulus
Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Cellular Protein Metabolic Process
Regulation Of Kinase Activity
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Mitotic Cell Cycle Phase Transition
Response To Virus
Cell Cycle Phase Transition
Catabolic Process
Regulation Of Catalytic Activity
Intracellular Receptor Signaling Pathway
Cell Cycle
Regulation Of Gene Expression
Positive Regulation Of Protein Metabolic Process
Protein Metabolic Process
Innate Immune Response
Positive Regulation Of Cellular Protein Metabolic Process
G1/S Transition Of Mitotic Cell Cycle
Mitotic Cell Cycle Process
Phosphate-containing Compound Metabolic Process
Cellular Protein Modification Process
Cell Cycle Process
Regulation Of Signal Transduction
Protein Catabolic Process
Mitotic Cell Cycle
TRIF-dependent Toll-like Receptor Signaling Pathway
MyD88-independent Toll-like Receptor Signaling Pathway
Signaling
Toll-like Receptor 3 Signaling Pathway
Regulation Of Signaling
Positive Regulation Of Signal Transduction
Cellular Response To Stimulus
Tagcloud
?
base
chick
clusters
conforms
consensus
copies
emphasize
exons
finger
flanking
gctat
ggg
glycosaminoglycans
homeodomain
hsp90
introns
kilobases
mzf1
pair
presumptive
promotion
reorganization
repetitive
s8
sizes
sp1
stabilization
striking
tatgggga
Tagcloud (Difference)
?
base
chick
clusters
conforms
consensus
copies
emphasize
exons
finger
flanking
gctat
ggg
glycosaminoglycans
homeodomain
hsp90
introns
kilobases
mzf1
pair
presumptive
promotion
reorganization
repetitive
s8
sizes
sp1
stabilization
striking
tatgggga
Tagcloud (Intersection)
?