TULP3 and PSTPIP1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid, two hybrid)

		TULP3	PSTPIP1
Description		TUB like protein 3	proline-serine-threonine phosphatase interacting protein 1
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GO Annotations	Cellular Component	Extracellular Region Nucleus Nucleoplasm Nucleolus Cytoplasm Plasma Membrane Cilium Axoneme Membrane Ciliary Basal Body Cell Projection Ciliary Base 9+0 Non-motile Cilium	Uropod Cytoplasm Cytosol Cytoskeleton Plasma Membrane Membrane Lamellipodium Cleavage Furrow Cell Projection Perinuclear Region Of Cytoplasm
	Molecular Function	G Protein-coupled Receptor Binding Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding Enzyme Binding Phosphatidylinositol Binding Protein-containing Complex Binding Intraciliary Transport Particle A Binding	Protein Binding Identical Protein Binding
	Biological Process	Neural Tube Formation Neural Tube Closure Regulation Of DNA-templated Transcription G Protein-coupled Receptor Signaling Pathway Smoothened Signaling Pathway Brain Development Regulation Of G Protein-coupled Receptor Signaling Pathway Regulation Of Smoothened Signaling Pathway Anterior/posterior Pattern Specification Dorsal/ventral Neural Tube Patterning Neural Tube Development Central Nervous System Neuron Differentiation Embryonic Camera-type Eye Development Embryonic Digit Morphogenesis Negative Regulation Of Smoothened Signaling Pathway Embryonic Neurocranium Morphogenesis Limb Development Bone Development Bronchus Morphogenesis Smoothened Signaling Pathway Involved In Dorsal/ventral Neural Tube Patterning Protein Localization To Cilium Ganglion Development	Immune System Process Endocytosis Inflammatory Response Cell Adhesion Signal Transduction Innate Immune Response
Pathways		Hedgehog 'off' state	The NLRP3 inflammasome Purinergic signaling in leishmaniasis infection
Drugs
Diseases			Pyogenic sterile arthritis, pyoderma gangrenosum, and acne (PAPA) syndrome
GWAS		Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494)	Hip circumference adjusted for BMI ( 34021172) Neurofibrillary tangles ( 31497858) Neutrophil count ( 32888494) White blood cell count ( 32888494)
Interacting Genes		61 interacting genes: ACTN2 AKAP9 ANKRD1 ARHGAP21 ARMCX2 ATP2A1 BACH2 BOC BRMS1L BTBD1 CCNB1 CHD2 CLIP4 DNTTIP2 DROSHA DST ESRRG GPATCH2L GSE1 HSF2BP KIF3A KLF10 KRTAP10-1 KRTAP10-5 KRTAP10-7 MAGEA6 MAP3K5 MBTD1 MGA MORF4L1 MYBPC2 MYH3 MYH7 MYO18B NCOR1 NFE2L1 NOSTRIN NRIP1 PAF1 PCGF6 PDE4DIP PHAX PSTPIP1 RCOR3 RIOK3 RNF10 ROPN1 RYR1 SLAIN2 SPTB SRP72 TNNT1 TNNT3 WNK1 ZFAT ZNF160 ZNF462 ZNF619 ZNF793 ZNF835 ZSCAN23	64 interacting genes: ABL1 AXIN1 BUB3 CCDC172 CD2 CD2AP CHD4 CWF19L2 DHX40 DNM2 EHHADH EXOC5 FAM90A1 FASLG FBXL18 HAPLN2 HHEX HMG20A HSF2BP IL16 KANK2 KHDRBS1 LIN37 LSM4 MCRS1 MEFV MOS MVP NAV2 NCBP1 PCDHB14 PNKP PRPF31 PRR35 PTPN12 PTPN18 RINT1 RNPS1 RPL9 RTP5 RXRB SCNM1 SDCBP SH2D4A SHBG SMARCD1 SPG7 SYCE1 TFIP11 TPH1 TRAF3IP3 TSGA10IP TTC1 TULP3 UBE2W WAS WASF1 WASF2 WASL ZC2HC1C ZNF175 ZNF408 ZNF580 ZNF688
Entrez ID		7289	9051
HPRD ID		05292	05891
Ensembl ID		ENSG00000078246	ENSG00000140368
Uniprot IDs		B7Z1E7 O75386	A0A0S2Z5P3 J3KPG6 O43586
PDB IDs		8FH3	2DIL 7AAL 7AAM 7AAN
Enriched GO Terms of Interacting Partners?		Sarcomere Organization Actomyosin Structure Organization Cytoskeleton Organization Regulation Of RNA Metabolic Process Myosin Filament Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Skeletal Muscle Contraction Actin Filament-based Process H Zone Striated Muscle Contraction Myofibril Actin Cytoskeleton Organization Sarcomere Actin Binding Regulation Of Transcription By RNA Polymerase II Regulation Of Gene Expression Microtubule Plus-end Myosin II Complex Organelle Organization I Band Histone Deacetylase Binding Z Disc Extrinsic Component Of Postsynaptic Density Membrane Striated Muscle Cell Development Regulation Of Macromolecule Biosynthetic Process Microtubule Cytoskeleton Organization Positive Regulation Of Microtubule Polymerization DNA Binding Transition Between Fast And Slow Fiber Muscle System Process Negative Regulation Of RNA Metabolic Process Troponin Complex Cardiac Muscle Cell Development Muscle Cell Development Nucleus Positive Regulation Of RNA Metabolic Process Histone Deacetylase Complex Regulation Of Primary Metabolic Process Cardiac Cell Development Microtubule-based Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Regulation Of Skeletal Muscle Adaptation Myosin Complex Actin Filament Binding	Actin Filament Polymerization Protein Polymerization MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Actin Polymerization Or Depolymerization SH3 Domain Binding Negative Regulation Of Membrane Tubulation Protein Binding Regulation Of Plasma Membrane Organization MRNA Processing RNA Splicing MRNA Metabolic Process Regulation Of ERBB Signaling Pathway Regulation Of Double-strand Break Repair Via Nonhomologous End Joining Spliceosomal Tri-snRNP Complex Regulation Of Double-strand Break Repair Regulation Of DNA Repair Negative Regulation Of ERBB Signaling Pathway Lamellipodium Morphogenesis Negative Regulation Of Cellular Component Organization Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation Actin Filament Organization Podosome Regulation Of Vitamin D Receptor Signaling Pathway Substrate-dependent Cell Migration, Cell Extension Spliceosomal Complex Actin Cytoskeleton Ruffle SCAR Complex
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