TULP3 and ZNF462

Number of citations of the paper that reports this interaction (PubMedID 23414517)
48

Data Source:
BioGRID (two hybrid)

		TULP3	ZNF462
Description		TUB like protein 3	zinc finger protein 462
Image
GO Annotations	Cellular Component	Extracellular Region Nucleus Nucleoplasm Nucleolus Cytoplasm Plasma Membrane Cilium Axoneme Membrane Ciliary Basal Body Cell Projection Ciliary Base 9+0 Non-motile Cilium	Nucleus Nucleoplasm
	Molecular Function	G Protein-coupled Receptor Binding Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding Enzyme Binding Phosphatidylinositol Binding Protein-containing Complex Binding Intraciliary Transport Particle A Binding	DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Neural Tube Formation Neural Tube Closure Regulation Of DNA-templated Transcription G Protein-coupled Receptor Signaling Pathway Smoothened Signaling Pathway Brain Development Regulation Of G Protein-coupled Receptor Signaling Pathway Regulation Of Smoothened Signaling Pathway Anterior/posterior Pattern Specification Dorsal/ventral Neural Tube Patterning Neural Tube Development Central Nervous System Neuron Differentiation Embryonic Camera-type Eye Development Embryonic Digit Morphogenesis Negative Regulation Of Smoothened Signaling Pathway Embryonic Neurocranium Morphogenesis Limb Development Bone Development Bronchus Morphogenesis Smoothened Signaling Pathway Involved In Dorsal/ventral Neural Tube Patterning Protein Localization To Cilium Ganglion Development	Chromatin Organization Positive Regulation Of Transcription By RNA Polymerase II
Pathways		Hedgehog 'off' state
Drugs
Diseases
GWAS		Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494)	Adult body size ( 32376654) Adverse response to chemotherapy in breast cancer (alopecia) (anti-microtubule) ( 24025145) Age at voice drop ( 27182965) Alcohol consumption ( 31358974) Alcohol consumption (drinks per week) ( 30679032) Atrial fibrillation ( 29892015) Body size at age 10 ( 32376654) Brain morphology (MOSTest) ( 32665545) Chronotype ( 30696823) Cognitive decline rate in late mild cognitive impairment ( 26252872) Cutaneous malignant melanoma ( 26237428) Diastolic blood pressure ( 30224653) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Emphysema imaging phenotypes ( 26030696) Height ( 28552196 31562340 18391951 20881960) Hip circumference adjusted for BMI ( 34021172) Lung function (FEV1/FVC) ( 30061609) Male-pattern baldness ( 28196072) Menarche (age at onset) ( 27182965 19448620) Mosaic loss of chromosome Y (Y chromosome dosage) ( 31624269) Red blood cell count ( 32888494) Refractive error ( 32231278) Regular attendance at a pub or social club ( 29970889) Risk-taking tendency (4-domain principal component model) ( 30643258) Smoking status (ever vs never smokers) ( 30643258) Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction) ( 28448500) Waist circumference adjusted for body mass index ( 28448500)
Interacting Genes		61 interacting genes: ACTN2 AKAP9 ANKRD1 ARHGAP21 ARMCX2 ATP2A1 BACH2 BOC BRMS1L BTBD1 CCNB1 CHD2 CLIP4 DNTTIP2 DROSHA DST ESRRG GPATCH2L GSE1 HSF2BP KIF3A KLF10 KRTAP10-1 KRTAP10-5 KRTAP10-7 MAGEA6 MAP3K5 MBTD1 MGA MORF4L1 MYBPC2 MYH3 MYH7 MYO18B NCOR1 NFE2L1 NOSTRIN NRIP1 PAF1 PCGF6 PDE4DIP PHAX PSTPIP1 RCOR3 RIOK3 RNF10 ROPN1 RYR1 SLAIN2 SPTB SRP72 TNNT1 TNNT3 WNK1 ZFAT ZNF160 ZNF462 ZNF619 ZNF793 ZNF835 ZSCAN23	3 interacting genes: CFTR FBXO7 TULP3
Entrez ID		7289	58499
HPRD ID		05292	10333
Ensembl ID		ENSG00000078246	ENSG00000148143
Uniprot IDs		B7Z1E7 O75386	Q96JM2
PDB IDs		8FH3	1X6F
Enriched GO Terms of Interacting Partners?		Sarcomere Organization Actomyosin Structure Organization Cytoskeleton Organization Regulation Of RNA Metabolic Process Myosin Filament Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Skeletal Muscle Contraction Actin Filament-based Process H Zone Striated Muscle Contraction Myofibril Actin Cytoskeleton Organization Sarcomere Actin Binding Regulation Of Transcription By RNA Polymerase II Regulation Of Gene Expression Microtubule Plus-end Myosin II Complex Organelle Organization I Band Histone Deacetylase Binding Z Disc Extrinsic Component Of Postsynaptic Density Membrane Striated Muscle Cell Development Regulation Of Macromolecule Biosynthetic Process Microtubule Cytoskeleton Organization Positive Regulation Of Microtubule Polymerization DNA Binding Transition Between Fast And Slow Fiber Muscle System Process Negative Regulation Of RNA Metabolic Process Troponin Complex Cardiac Muscle Cell Development Muscle Cell Development Nucleus Positive Regulation Of RNA Metabolic Process Histone Deacetylase Complex Regulation Of Primary Metabolic Process Cardiac Cell Development Microtubule-based Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Regulation Of Skeletal Muscle Adaptation Myosin Complex Actin Filament Binding	Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Glial Cytoplasmic Inclusion Classical Lewy Body Lewy Body Corona Lewy Neurite Positive Regulation Of Anion Channel Activity Bronchus Morphogenesis Positive Regulation Of Monoatomic Anion Transport Intraciliary Transport Particle A Binding Lewy Body Core Positive Regulation Of Enamel Mineralization Smoothened Signaling Pathway Involved In Dorsal/ventral Neural Tube Patterning Transepithelial Water Transport Positive Regulation Of Tooth Mineralization Chloride Channel Inhibitor Activity Chloride Channel Regulator Activity Regulation Of Enamel Mineralization Membrane Hyperpolarization Bicarbonate Transmembrane Transporter Activity Intracellular PH Elevation Embryonic Neurocranium Morphogenesis Enzyme Binding Amelogenesis Neural Tube Formation ATPase-coupled Inorganic Anion Transmembrane Transporter Activity 9+0 Non-motile Cilium Dorsal/ventral Neural Tube Patterning Regulation Of Monoatomic Anion Transport Epithelial Fluid Transport Golgi-associated Vesicle Membrane Negative Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Cellular Response To Forskolin Embryonic Camera-type Eye Development Animal Organ Morphogenesis Ganglion Development Response To Forskolin Chloride Transmembrane Transporter Activity Sperm Capacitation Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Bicarbonate Transport Positive Regulation Of Mitophagy Water Transport Embryonic Epithelial Tube Formation Cellular Developmental Process Positive Regulation Of Autophagy Of Mitochondrion Multicellular Organismal-level Water Homeostasis Protein Targeting To Mitochondrion Positive Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?