TSNAX and CARD9

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		TSNAX	CARD9
Gene Name		translin-associated factor X	caspase recruitment domain family, member 9
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Golgi Apparatus Cytosol Perinuclear Region Of Cytoplasm	Cytoplasm
	Molecular Function	DNA Binding Single-stranded DNA Binding Endoribonuclease Activity Protein Transporter Activity Sequence-specific DNA Binding Poly(A) RNA Binding Metal Ion Binding	Protein Homodimerization Activity CARD Domain Binding
	Biological Process	Multicellular Organismal Development Spermatogenesis Gene Expression Protein Transport Cell Differentiation RNA Phosphodiester Bond Hydrolysis, Endonucleolytic	Response To Fungus Response To Peptidoglycan Response To Muramyl Dipeptide Positive Regulation Of Interleukin-6 Production Positive Regulation Of Tumor Necrosis Factor Production Positive Regulation Of Stress-activated MAPK Cascade Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Response To Drug Regulation Of Tumor Necrosis Factor Biosynthetic Process Regulation Of Apoptotic Process Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Response To Exogenous DsRNA Regulation Of Interleukin-2 Biosynthetic Process Innate Immune Response Regulation Of Interleukin-6 Biosynthetic Process Positive Regulation Of JNK Cascade Defense Response To Gram-positive Bacterium Defense Response To Virus Nucleotide-binding Oligomerization Domain Containing Signaling Pathway
Pathways		Regulatory RNA pathways Small interfering RNA (siRNA) biogenesis	Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways NOD1/2 Signaling Pathway Innate Immune System
Drugs
Diseases
GWAS			Ankylosing spondylitis ( 21743469) Crohn's disease ( 22936669 21102463) Inflammatory bowel disease ( 23128233) Monocyte chemoattractant protein-1 ( 23017229) Obesity-related traits ( 23251661) Ulcerative colitis ( 19915572 20228799 21297633)
Protein-Protein Interactions		22 interactors: AIMP1 AKAP9 BLOC1S5 C1D CARD9 CDK5RAP2 CKAP4 GADD45G GOLGA3 KCNE4 KLC3 LDB2 LZTS2 MRFAP1L1 NSMCE2 PBXIP1 RALYL SUMO1 SUN1 TCF12 TSN TSNAXIP1	65 interactors: ABLIM1 AES ALS2CR11 AMOTL2 BCL10 BLZF1 C1orf94 CCDC36 CCDC85B CCHCR1 CDCA7L CEP57L1 CEP70 CSNK2A1 CWF19L2 DAXX DUSP13 EIF4E2 FAM124B FAM161A FAM208B FAM50B HMBOX1 IQCE KCTD9 KIAA0408 KIF9 KRT19 KRT31 KRT40 KRTAP10-1 KRTAP10-3 KRTAP10-5 LENG1 LMO1 LZTS2 MEOX2 MFAP1 NECAB2 PAK7 PBX2 PHC2 PNMA5 PPP1R18 RTP5 SSX2IP STX11 SUMO1 TCEANC TCL1A TFIP11 TNFAIP1 TRIM23 TRIM29 TRIM42 TRIM54 TSNAX USP15 VPS28 ZCCHC7 ZNF250 ZNF417 ZNF572 ZNF587 ZNF655
Entrez ID		7257	64170
HPRD ID		04270	06236
Ensembl ID		ENSG00000116918	ENSG00000187796
Uniprot IDs		Q99598	Q9H257
PDB IDs		3PJA 3QB5
Enriched GO Terms of Interacting Partners?		Protein Sumoylation Developmental Process Positive Regulation Of Cellular Metabolic Process Axon Cargo Transport Nuclear Envelope Organization Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Multicellular Organismal Development Positive Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Maintenance Of Mitotic Sister Chromatid Cohesion Cellular Localization Mitotic Cell Cycle Process	Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Gene Expression Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process RNA Metabolic Process Organelle Organization Regulation Of Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Nucleobase-containing Compound Metabolic Process Developmental Process Regulation Of Cellular Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Wnt Signaling Pathway Spliceosomal Complex Disassembly Organelle Assembly Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Gene Expression Positive Regulation Of Mast Cell Cytokine Production Histone H2B Conserved C-terminal Lysine Deubiquitination Lymphotoxin A Biosynthetic Process Interleukin-6 Biosynthetic Process Negative Regulation Of Biosynthetic Process
Tagcloud ?		bdi beadstation bipolar chinese disorder edition fourth genotyped genotyping goldengate guangzhou han haplotype haplotypes illumina lis1 lis1and machine manual meeting plink polymorphisms psychotic snp snps software statistic subgroups ten	adapter assembly danger defense discuss engaged framework fungal homeostasis inducible innate lectin links lymphoid lymphoma malt mucosa multifunctional nonredundant oligomerization paracaspase polymorphisms responds rig rlrs sensors spleen syk
Tagcloud (Difference) ?		bdi beadstation bipolar chinese disorder edition fourth genotyped genotyping goldengate guangzhou han haplotype haplotypes illumina lis1 lis1and machine manual meeting plink psychotic snp snps software statistic subgroups ten	adapter assembly danger defense discuss engaged framework fungal homeostasis inducible innate lectin links lymphoid lymphoma malt mucosa multifunctional nonredundant oligomerization paracaspase responds rig rlrs sensors spleen syk
Tagcloud (Intersection) ?		polymorphisms