TSNAX and AKAP9

Number of citations of the paper that reports this interaction (PMID 12036294)
5

Data Source:
HPRD (in vitro, in vivo)

		TSNAX	AKAP9
Gene Name		translin-associated factor X	A kinase (PRKA) anchor protein 9
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Golgi Apparatus Cytosol Perinuclear Region Of Cytoplasm	Pericentriolar Material Golgi Apparatus Centrosome Cytosol Cytoskeleton Voltage-gated Potassium Channel Complex Ciliary Basal Body Intracellular Membrane-bounded Organelle
	Molecular Function	DNA Binding Single-stranded DNA Binding Endoribonuclease Activity Protein Transporter Activity Sequence-specific DNA Binding Poly(A) RNA Binding Metal Ion Binding	Receptor Binding Protein Binding Potassium Channel Regulator Activity Protein Complex Scaffold Ion Channel Binding
	Biological Process	Multicellular Organismal Development Spermatogenesis Gene Expression Protein Transport Cell Differentiation RNA Phosphodiester Bond Hydrolysis, Endonucleolytic	G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Transport Organelle Organization Signal Transduction Synaptic Transmission Spermatogenesis Positive Regulation Of Peptidyl-serine Phosphorylation Sertoli Cell Development Regulation Of Membrane Repolarization Regulation Of Ventricular Cardiac Muscle Cell Membrane Repolarization Cellular Response To CAMP Regulation Of Heart Rate By Cardiac Conduction Positive Regulation Of Potassium Ion Transmembrane Transporter Activity
Pathways		Regulatory RNA pathways Small interfering RNA (siRNA) biogenesis	Organelle biogenesis and maintenance Assembly of the primary cilium G2/M Transition CREB phosphorylation through the activation of Ras Regulation of PLK1 Activity at G2/M Transition Anchoring of the basal body to the plasma membrane Cell Cycle, Mitotic Loss of proteins required for interphase microtubule organizationÂ from the centrosome Activation of NMDA receptor upon glutamate binding and postsynaptic events Loss of Nlp from mitotic centrosomes CREB phosphorylation through the activation of CaMKII Centrosome maturation Mitotic G2-G2/M phases Unblocking of NMDA receptor, glutamate binding and activation Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell Recruitment of mitotic centrosome proteins and complexes Ras activation uopn Ca2+ infux through NMDA receptor Post NMDA receptor activation events Transmission across Chemical Synapses
Drugs
Diseases
GWAS
Protein-Protein Interactions		22 interactors: AIMP1 AKAP9 BLOC1S5 C1D CARD9 CDK5RAP2 CKAP4 GADD45G GOLGA3 KCNE4 KLC3 LDB2 LZTS2 MRFAP1L1 NSMCE2 PBXIP1 RALYL SUMO1 SUN1 TCF12 TSN TSNAXIP1	43 interactors: BLZF1 C1orf94 CALM1 CALM2 CALM3 CCP110 CDC5L CEP55 CLIC1 CSNK1D CSNK1E DISC1 FNBP1 GRIN1 HNRNPM IKZF3 KCNQ1 KDM1A MAGEA6 MAGED1 PCNT PKN1 PPP1CA PPP2R1B PPP2R3A PRDM14 PRKAR2A PRKAR2B PRKCE SAMD3 SSX2 SUV39H2 TACC3 TDP2 THAP1 TNIK TRIP10 TSG101 TSNAX TUBGCP3 USHBP1 USO1 WAC
Entrez ID		7257	10142
HPRD ID		04270	04921
Ensembl ID		ENSG00000116918	ENSG00000127914
Uniprot IDs		Q99598	Q5GIA7 Q6PJH3 Q99996
PDB IDs		3PJA 3QB5
Enriched GO Terms of Interacting Partners?		Protein Sumoylation Developmental Process Positive Regulation Of Cellular Metabolic Process Axon Cargo Transport Nuclear Envelope Organization Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Multicellular Organismal Development Positive Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Maintenance Of Mitotic Sister Chromatid Cohesion Cellular Localization Mitotic Cell Cycle Process	Cell Cycle Activation Of Phospholipase C Activity Positive Regulation Of Phospholipase C Activity Organelle Organization Positive Regulation Of Phospholipase Activity Regulation Of Phospholipase Activity Positive Regulation Of Lipase Activity G2/M Transition Of Mitotic Cell Cycle Regulation Of Cytokinesis Neurotrophin TRK Receptor Signaling Pathway Positive Regulation Of Cyclic-nucleotide Phosphodiesterase Activity Neurotrophin Signaling Pathway Regulation Of Signaling Energy Reserve Metabolic Process Regulation Of High Voltage-gated Calcium Channel Activity Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Epidermal Growth Factor Receptor Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Response To Amphetamine Blood Coagulation Positive Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Positive Regulation Of Protein Metabolic Process Hemostasis Regulation Of Circadian Rhythm Cell Cycle Process Cellular Response To Fibroblast Growth Factor Stimulus Negative Regulation Of Transporter Activity Response To Fibroblast Growth Factor Positive Regulation Of Protein Kinase Activity Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Regulation Of Protein Metabolic Process Positive Regulation Of Phosphorylation Positive Regulation Of Kinase Activity Positive Regulation Of Cellular Protein Metabolic Process Detection Of Calcium Ion Negative Regulation Of Ion Transmembrane Transport Response To Amine Positive Regulation Of Protein Modification Process Regulation Of Cellular Protein Metabolic Process Regulation Of Cell Communication By Electrical Coupling Regulation Of Cell Cycle Positive Regulation Of Phosphoprotein Phosphatase Activity Positive Regulation Of Protein Phosphorylation Regulation Of Metabolic Process Negative Regulation Of Transmembrane Transport Mitotic Cell Cycle Positive Regulation Of Transferase Activity Positive Regulation Of Peptidyl-threonine Phosphorylation Positive Regulation Of Protein Autophosphorylation
Tagcloud ?		bdi beadstation bipolar chinese disorder edition fourth genotyped genotyping goldengate guangzhou han haplotype haplotypes illumina lis1 lis1and machine manual meeting plink polymorphisms psychotic snp snps software statistic subgroups ten	akap450 disrupting eb1 endoplasmic fragmentation functioned golgi immunoprecipitation interacting isoform mapre1 microtubule microtubules mmg8 myomegalin networks newly nucleation obscure organization organizing participates predominantly reticulum thereby tracking trafficking tubulin variant
Tagcloud (Difference) ?		bdi beadstation bipolar chinese disorder edition fourth genotyped genotyping goldengate guangzhou han haplotype haplotypes illumina lis1 lis1and machine manual meeting plink polymorphisms psychotic snp snps software statistic subgroups ten	akap450 disrupting eb1 endoplasmic fragmentation functioned golgi immunoprecipitation interacting isoform mapre1 microtubule microtubules mmg8 myomegalin networks newly nucleation obscure organization organizing participates predominantly reticulum thereby tracking trafficking tubulin variant
Tagcloud (Intersection) ?