TSNAX and BLOC1S5

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid, two hybrid)

		TSNAX	BLOC1S5
Description		translin associated factor X	biogenesis of lysosomal organelles complex 1 subunit 5
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Cytosol Perinuclear Region Of Cytoplasm Endoribonuclease Complex	Transport Vesicle BLOC-1 Complex Axon Cytoplasm Microvesicle
	Molecular Function	DNA Binding Single-stranded DNA Binding RNA Binding RNA Endonuclease Activity Protein Binding A2A Adenosine Receptor Binding Sequence-specific DNA Binding Protein-containing Complex Binding Metal Ion Binding	Protein Binding
	Biological Process	Spermatogenesis Cell Differentiation SiRNA Processing Regulatory NcRNA-mediated Post-transcriptional Gene Silencing	Anterograde Axonal Transport Vesicle-mediated Transport Neuron Projection Development Melanosome Transport Melanosome Organization Otolith Morphogenesis Endosome To Melanosome Transport Developmental Pigmentation Anterograde Synaptic Vesicle Transport Positive Regulation Of Pigment Cell Differentiation
Pathways		Small interfering RNA (siRNA) biogenesis
Drugs
Diseases
GWAS		Chronic periodontitis (mean interproximal clinical attachment level) ( 27601451) Metabolite levels ( 23823483)	Response to (pegylated) interferon in HBeAg-negative hepatitis B ( 30715261)
Interacting Genes		41 interacting genes: AIMP1 AKAP9 BEX3 BLOC1S5 C1D CARD9 CDK5RAP2 CEBPA CEP68 CKAP4 COG6 EMILIN1 GADD45G GOLGA3 GPATCH2 GRIPAP1 HMGB2 KCNE4 KRT31 LDB2 LDOC1 LZTS2 MECOM MRFAP1L1 MTCL2 NSMCE2 NTAQ1 PBXIP1 PRPF18 RALYL RFC5 SPRED2 SUN1 SYCE2 SYT17 TCF12 TCP11L1 TSN TSNAXIP1 UBE2I VPS28	15 interacting genes: ABI2 ABI3 APP BLOC1S1 BLOC1S2 BLOC1S4 DTNBP1 HSBP1 LRRK1 OIP5 PBX2 PKNOX1 SMARCD1 SNAPIN TSNAX
Entrez ID		7257	63915
HPRD ID		04270	06289
Ensembl ID		ENSG00000116918	ENSG00000188428
Uniprot IDs		Q99598	A0A0A0MTN6 Q8TDH9
PDB IDs		3PJA 3QB5
Enriched GO Terms of Interacting Partners?			Axo-dendritic Transport Anterograde Synaptic Vesicle Transport BLOC-1 Complex Axon Cytoplasm Axonal Transport Transport Along Microtubule Organelle Transport Along Microtubule Synaptic Vesicle Transport Melanosome Organization Pigment Granule Organization Cytoskeleton-dependent Intracellular Transport Microtubule-based Transport Vesicle Transport Along Microtubule Anterograde Axonal Transport Vesicle Cytoskeletal Trafficking Microtubule-based Movement Establishment Of Vesicle Localization Regulation Of Lysosome Size BORC Complex Vesicle Localization Establishment Of Organelle Localization Regulation Of Endosome Size Cytoplasmic Side Of Lysosomal Membrane Regulation Of Vesicle Size Cell Projection Organization Platelet Dense Granule Organization Organelle Localization Neuron Projection Development Microtubule-based Process Vesicle Organization Regulation Of Postsynapse Organization Regulation Of Dendritic Spine Morphogenesis Dendritic Spine Lysosome Localization Actin-based Cell Projection Secretory Granule Organization Intracellular Transport SCAR Complex Plasma Membrane Bounded Cell Projection Organization Cell Projection Morphogenesis Regulation Of Synapse Organization Cellular Localization Establishment Of Localization In Cell Regulation Of Plasma Membrane Bounded Cell Projection Organization Regulation Of Cell Projection Organization Positive Regulation Of Receptor Internalization Regulation Of Neuron Projection Development Hemopoiesis Negative Regulation Of Cell Projection Organization Regulation Of Lamellipodium Assembly
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