MZB1

Description		marginal zone B and B1 cell specific protein
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GO Annotations	Cellular Component	Extracellular Region Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endoplasmic Reticulum Chaperone Complex
	Molecular Function	Protein Binding
	Biological Process	Positive Regulation Of Immunoglobulin Production Apoptotic Process Positive Regulation Of Cell Population Proliferation Regulation Of B Cell Proliferation Integrin Activation Regulation Of Cell Population Proliferation Regulation Of Insulin Receptor Signaling Pathway
Pathways
Drugs
Diseases
GWAS		Body mass index ( 26426971) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Malaria ( 31844061)
Interacting Genes		4 interacting genes: CASP2 CASP9 MAPK6 TSG101
Entrez ID		51237
HPRD ID		17815
Ensembl ID		ENSG00000170476
Uniprot IDs		B3KQ72 Q8WU39
PDB IDs		7AAH
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Neuron Apoptotic Process Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Cysteine-type Endopeptidase Activity Cysteine-type Peptidase Activity Intrinsic Apoptotic Signaling Pathway Signal Transduction In Response To DNA Damage Protein Processing Endopeptidase Complex Apoptosome Caspase Complex Septin Cytoskeleton Positive Regulation Of Ubiquitin-dependent Endocytosis Positive Regulation Of Viral Budding Via Host ESCRT Complex Protein Metabolic Process Exosomal Secretion Luteolysis Regulation Of Neuron Apoptotic Process Proteolysis Response To Anesthetic Glial Cell Apoptotic Process Response To Indole-3-methanol Regulation Of Extracellular Exosome Assembly Protein Maturation Apoptotic Signaling Pathway Negative Regulation Of Epidermal Growth Factor-activated Receptor Activity Response To Cobalt Ion Virion Binding Fibroblast Apoptotic Process ESCRT I Complex Negative Regulation Of Protein Tyrosine Kinase Activity Negative Regulation Of Signaling Receptor Activity Positive Regulation Of Exosomal Secretion Ectopic Germ Cell Programmed Cell Death Peptidase Activity Neural Retina Development Intracellular Signal Transduction Protein Kinase Binding MAP Kinase Activity Protein Transport To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Regulation Of Exosomal Secretion Negative Regulation Of Peptidyl-tyrosine Phosphorylation Programmed Cell Death Involved In Cell Development Positive Regulation Of Execution Phase Of Apoptosis Viral Budding Via Host ESCRT Complex Regulation Of Protein Tyrosine Kinase Activity Platelet Formation Positive Regulation Of Programmed Cell Death Positive Regulation Of Apoptotic Process Macromolecule Metabolic Process Execution Phase Of Apoptosis
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