TRIP6 and TXN2

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		TRIP6	TXN2
Gene Name		thyroid hormone receptor interactor 6	thioredoxin 2
Image
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Cytoskeleton Plasma Membrane Focal Adhesion Interleukin-1 Receptor Complex	Nucleolus Mitochondrion Mitochondrial Matrix Dendrite Neuronal Cell Body
	Molecular Function	Interleukin-1 Receptor Binding Protein Binding Zinc Ion Binding Kinase Binding Poly(A) RNA Binding Thyroid Hormone Receptor Binding	Peptide-methionine (S)-S-oxide Reductase Activity Protein Disulfide Oxidoreductase Activity Protein Complex Binding Peptide-methionine (R)-S-oxide Reductase Activity
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Release Of Cytoplasmic Sequestered NF-kappaB Positive Regulation Of Cell Migration Focal Adhesion Assembly	Response To Reactive Oxygen Species Response To Hypoxia Glycerol Ether Metabolic Process Response To Nutrient Response To Hormone Response To Glucose Response To Organic Cyclic Compound Cellular Response To Nutrient Levels Response To Drug Cell Redox Homeostasis Response To Axon Injury Oxidation-reduction Process
Pathways			Detoxification of Reactive Oxygen Species
Drugs
Diseases
GWAS		Plasminogen activator inhibitor type 1 levels (PAI-1) ( 22990020)
Protein-Protein Interactions		105 interactors: ABI2 ADAMTSL4 AQP1 ARNT2 ATN1 ATP5O ATXN1 BCAR1 BYSL CATSPER1 CBLC CCL5 CEP57L1 CNTF CREB5 CTAG2 DHX37 DMRT3 DTX2 EXOC3-AS1 FAM124B FAM154A FAM46C FASLG FHL3 FRS3 GDPD5 GFI1B GNAI2 GSE1 HLA-DPB1 HOXA1 HOXA9 HOXB9 HYKK ILF3 INCA1 KIAA1683 KIF1A KIR2DL4 KLK15 KRTAP26-1 LMO2 LOC149950 LPAR2 MAPKBP1 MEMO1 METTL17 MSRB3 MVP NCK2 NEDD9 NEU4 NUP210 ODF1 OIP5 OTUB2 PDGFRB PDLIM4 PIN1 POM121 POM121L4P PPP1R16A PRKAA1 PRKAA2 PTK2 PTPN13 PXN RAD23A RERE RFX3 RHOA RHOQ RNF213 RNF214 SCRIB SIK3 SLC15A3 SLC25A6 SMAD1 SON SRC STAC STK16 SVIL SYNGAP1 TAB1 TCAF1 TEKT4 THRB TLR2 TMSB4X TPM3 TPM4 TRAF3IP2 TRAPPC2L TRIM29 TTLL10 TXN2 TXNDC5 VCL WT1-AS XRCC6BP1 YPEL3 ZBP1	34 interactors: AGTRAP ALDOB AP2B1 CCDC114 DCTD FAM9B GPRASP2 KRT18 KRT40 MAGEA11 MAPRE2 MAPRE3 MLH1 MRFAP1L1 MTUS2 PPCDC PSME3 RABAC1 RABGEF1 RBM45 REEP6 RPIA SCYL3 SHARPIN SSNA1 STUB1 THAP1 TIFA TRIM21 TRIP6 UCHL5 VIM VPS52 ZBTB14
Entrez ID		7205	25828
HPRD ID		04242	07161
Ensembl ID		ENSG00000087077	ENSG00000100348
Uniprot IDs		F2ZC06 Q15654	B4DX69 Q99757
PDB IDs		1X61 2DLO	1UVZ 1W4V 1W89
Enriched GO Terms of Interacting Partners?		Signal Complex Assembly Cellular Response To Organic Substance Positive Regulation Of Cellular Metabolic Process Response To Organic Substance Regulation Of Signaling Actin Filament-based Process Regulation Of Intracellular Signal Transduction Regulation Of Signal Transduction Movement Of Cell Or Subcellular Component Positive Regulation Of Intracellular Signal Transduction Response To Growth Factor Cytoskeleton Organization Vascular Endothelial Growth Factor Receptor Signaling Pathway Regulation Of Protein Kinase Activity Positive Regulation Of Signal Transduction ERBB Signaling Pathway Cell Communication Cellular Process Cell Surface Receptor Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Phosphorylation Multicellular Organismal Development Regulation Of Apoptotic Process Response To Stimulus Cellular Response To Transforming Growth Factor Beta Stimulus Regulation Of Cellular Process Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Kinase Activity Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Metabolic Process Response To Transforming Growth Factor Beta Regulation Of Protein Phosphorylation Cellular Response To Stimulus Platelet Activation Response To Hormone Response To Stress Cellular Response To Growth Factor Stimulus Response To Wounding Regulation Of Protein Metabolic Process Regulation Of Cell Death Actin Cytoskeleton Organization Wound Healing Signaling Transforming Growth Factor Beta Receptor Signaling Pathway Organ Development Regulation Of Cell Motility Cell Motility Regulation Of Phosphorus Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Apoptotic Process	Protein Polyubiquitination Cell Cycle Protein Ubiquitination Protein Modification By Small Protein Conjugation Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Protein Autoubiquitination Negative Regulation Of Kit Signaling Pathway Meiotic Metaphase I Plate Congression Golgi To Plasma Membrane CFTR Protein Transport Meiotic Spindle Midzone Assembly Regulation Of Proteasomal Protein Catabolic Process I-kappaB Kinase/NF-kappaB Signaling Signal Transduction Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Positive Regulation Of Chaperone-mediated Protein Complex Assembly Negative Regulation Of Mitotic Recombination Positive Regulation Of Microtubule Plus-end Binding Fructose Catabolic Process Embryonic Ectodermal Digestive Tract Development Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Viral Process Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Positive Regulation Of Ubiquitin-protein Transferase Activity Execution Phase Of Apoptosis Nucleotide Metabolic Process Positive Regulation Of Ligase Activity Negative Regulation Of Protein Deubiquitination Regulation Of CD40 Signaling Pathway Protein Linear Polyubiquitination Positive Regulation Of Cell Cycle Apoptotic Process Signaling Nicotinamide Nucleotide Metabolic Process Regulation Of Ubiquitin-protein Transferase Activity Regulation Of Mitotic Recombination Pentose-phosphate Shunt, Non-oxidative Branch Fructose 1,6-bisphosphate Metabolic Process Male Meiosis Chromosome Segregation Positive Regulation Of Viral Entry Into Host Cell Programmed Cell Death Cell Communication Protein Complex Assembly Cell Cycle Process Regulation Of Cytokine-mediated Signaling Pathway Cell Death Nucleobase-containing Small Molecule Metabolic Process Death Negative Regulation Of Interleukin-6 Secretion Ciliary Receptor Clustering Involved In Smoothened Signaling Pathway
Tagcloud ?		adaptors ap competition dimerization discrete domains enables enhances example exerts focal glucocorticoid gr interacts intriguing isoform lim med1 mediating mediator negatively orchestrating promoters recruitment tethering thought thrap3 transrepression
Tagcloud (Difference) ?		adaptors ap competition dimerization discrete domains enables enhances example exerts focal glucocorticoid gr interacts intriguing isoform lim med1 mediating mediator negatively orchestrating promoters recruitment tethering thought thrap3 transrepression
Tagcloud (Intersection) ?