TRIP6 and TENT5C

Number of citations of the paper that reports this interaction (PubMedID 16189514)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		TRIP6	TENT5C
Description		thyroid hormone receptor interactor 6	terminal nucleotidyltransferase 5C
Image
GO Annotations	Cellular Component	Stress Fiber Nucleus Cytoplasm Cytosol Cytoskeleton Plasma Membrane Focal Adhesion Anchoring Junction	Nucleus Nucleoplasm Cytoplasm Centrosome Cytoskeleton
	Molecular Function	RNA Binding Interleukin-1 Receptor Binding Protein Binding Kinase Binding Metal Ion Binding Nuclear Thyroid Hormone Receptor Binding	RNA Binding Protein Binding Transferase Activity Nucleotidyltransferase Activity Poly(A) RNA Polymerase Activity
	Biological Process	Cell Adhesion Signal Transduction Positive Regulation Of Cell Migration Chordate Embryonic Development Focal Adhesion Assembly Positive Regulation Of Non-canonical NF-kappaB Signal Transduction	In Utero Embryonic Development Negative Regulation Of Cell Differentiation MRNA Stabilization
Pathways
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756) Heart rate increase in response to exercise ( 29497042) Heart rate response to recovery post exercise (10 sec) ( 29497042) Heart rate response to recovery post exercise (20 sec) ( 29497042) Heart rate response to recovery post exercise (30 sec) ( 29497042) Heart rate response to recovery post exercise (40 sec) ( 29497042) Heart rate response to recovery post exercise (50 sec) ( 29497042) Nonunion in individuals with fractures ( 30680360) Plasminogen activator inhibitor type 1 levels (PAI-1) ( 22990020) Serum alkaline phosphatase levels ( 33547301)
Interacting Genes		164 interacting genes: ABI2 ADAMTSL4 AQP1 ARNT2 ATN1 ATP23 ATP5PO ATXN1 AXIN1 BAG3 BCAR1 BEX2 BYSL C11orf87 CATSPER1 CBLC CCDC120 CCDC187 CCDC24 CCL5 CEP57L1 CNTF CREB5 CRYBA4 CTAG2 DHX37 DMRT3 DTX2 EFHC1 EPDR1 ERBB2 EXOC3-AS1 FAM124B FAM222B FARS2 FAS FASLG FHL3 FOXD4L1 FRS3 GAD1 GATA1 GFI1B GLIS3 GNAI2 GNE GPS2 GSE1 HCK HLA-DPB1 HOXA1 HOXA9 HOXB9 HOXC8 HYKK IL16 ILF3 INCA1 IP6K3 IQCN ITGB4 KCTD9 KIF1A KIR2DL4 KLK15 KPRP KRTAP26-1 LMO2 LNX1 LPAR2 MAPKBP1 MEMO1 METTL17 MIEN1 MIIP MISP MSRB3 MVP NCK2 NEDD9 NEU4 NOL4L-DT NR1D2 NSMF NUP210 ODF1 OIP5 OTUB2 OTX1 PATZ1 PDGFRB PDLIM4 PER1 PIGS PIN1 PLEKHN1 POM121 POM121L4P PPDPF PPP1R16A PRKAA1 PRKAA2 PTK2 PTPN13 PTPN14 PXN RAD23A RANBP3L RERE RFX3 RHOA RHOQ RNF213 RNF214 SAXO1 SCAND1 SCRIB SETDB1 SHISA6 SIK3 SLC25A6 SMAD1 SMG9 SNAI1 SON SRC STAC STK16 SVIL SYNGAP1 TAB1 TBC1D22B TCAF1 TEKT4 TENT5C THRB TIE1 TLE5 TLR2 TMSB4X TPM3 TPM4 TRAF3IP2 TRAPPC2L TRIM29 TSGA10IP TSSK3 TTC23 TTLL10 TXN2 TXNDC5 USP2 VASN VCL WT1-AS YAP1 YPEL3 ZBP1 ZIC1 ZNF541 ZNF580 ZNF581 ZNF688 ZNF785	7 interacting genes: AP2B1 DAZAP2 MVP PLK4 PRKN RHOXF2 TRIP6
Entrez ID		7205	54855
HPRD ID		04242	13312
Ensembl ID		ENSG00000087077	ENSG00000183508
Uniprot IDs		Q15654	Q5VWP2
PDB IDs		1X61 2DLO	6W36 6W38 6W3I 6W3J 8EQB
Enriched GO Terms of Interacting Partners?		Protein Binding Regulation Of Apoptotic Process Regulation Of Programmed Cell Death Signal Complex Assembly Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Cell Surface Receptor Signaling Pathway Positive Regulation Of Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Peptidyl-tyrosine Phosphorylation Positive Regulation Of Metabolic Process Focal Adhesion Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Biosynthetic Process Stress Fiber Actin Filament Cell Motility Positive Regulation Of Macromolecule Metabolic Process Anchoring Junction Positive Regulation Of RNA Metabolic Process Actin Filament Organization Sequence-specific Double-stranded DNA Binding Cell Migration Nucleus Cytoskeleton Necroptotic Signaling Pathway Cytoplasm Histone H2BS36 Kinase Activity [hydroxymethylglutaryl-CoA Reductase (NADPH)] Kinase Activity ERBB Signaling Pathway Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Transcription Regulator Complex Anatomical Structure Morphogenesis Regulation Of Protein Localization To Nucleus Regulation Of Protein Localization RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Mesoderm Development Positive Regulation Of TOR Signaling Positive Regulation Of Locomotion Regulation Of Locomotion Positive Regulation Of Phosphate Metabolic Process Protein Tyrosine Kinase Activity Cold Acclimation Regulation Of RNA Metabolic Process Regulation Of Podosome Assembly Supramolecular Fiber Organization Regulation Of Cell Motility Positive Regulation Of Cell Migration Cell Cortex	Synaptic Vesicle Neurotransmitter Transport Clathrin Coat Positive Regulation Of Protein Localization To Membrane Regulation Of Protein Localization To Membrane Cellular Component Assembly Signal Sequence Binding Regulation Of Postsynaptic Membrane Neurotransmitter Receptor Levels Extrinsic Component Of Presynaptic Endocytic Zone Membrane Lewy Body Negative Regulation Of Catalytic Activity Regulation Of Spontaneous Synaptic Transmission Parkin-FBXW7-Cul1 Ubiquitin Ligase Complex Positive Regulation Of Retrograde Transport, Endosome To Golgi Negative Regulation Of Glucokinase Activity Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Regulation Protein Catabolic Process At Presynapse Type 2 Mitophagy Negative Regulation Of Intralumenal Vesicle Formation Negative Regulation Of Kinase Activity Dopamine Uptake Involved In Synaptic Transmission Negative Regulation Of Mitochondrial Fission Mitochondrion To Lysosome Vesicle-mediated Transport Regulation Of Endosome Organization Positive Regulation Of Mitochondrial Fusion Mitochondrion-derived Vesicle F-box Domain Binding Kinase Binding Positive Regulation Of Protein Linear Polyubiquitination Negative Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Cellular Response To Hydrogen Sulfide Positive Regulation Of Mitochondrial Membrane Potential Negative Regulation Of Spontaneous Neurotransmitter Secretion Protein Destabilization Response To Curcumin Aggresome Assembly Positive Regulation Of Neurotransmitter Uptake Negative Regulation Of Phosphorylation Cellular Response To L-glutamine Negative Regulation Of Phosphate Metabolic Process Regulation Of Synaptic Vesicle Transport Response To Hydrogen Sulfide Negative Regulation Of Exosomal Secretion Identical Protein Binding Negative Regulation Of Protein Autophosphorylation De Novo Centriole Assembly Involved In Multi-ciliated Epithelial Cell Differentiation De Novo Centriole Assembly Procentriole Replication Complex Procentriole Deuterosome
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