TOP2A and XPO1

  • Number of citations of the paper that reports this interaction (PMID 12821127)
  • 3
  • Data Source:
  • HPRD (in vitro, in vivo)

TOP2A

XPO1

Gene Name topoisomerase (DNA) II alpha 170kDa exportin 1
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 22 interactors: BRCA1 CDK1 COPS5 CSNK2A1 DFFB DHX9 HDAC1 HDAC2 JUN MAPK1 PIN1 PRKCA PRKCB PRKCG RB1 SRPK1 SUMO1 SUMO4 TOP2B TP53 XPO1 YWHAE 72 interactors: ABL1 ADAR AGFG1 AHR ANP32A ANP32B APC ATF2 BECN1 BIRC5 CCND1 CDC25A CDCA4 CDKN1B CHEK1 CHORDC1 CIITA CRK DDX3X DR1 E2F4 E2F5 EIF5A ERF FBXO7 FOXO4 HDAC3 HNF4A HSPA9 IRF5 KIF17 MAPK6 NF2 NMD3 NPM1 NUCB1 NUCB2 NUP153 NUP214 NUP50 NUP62 NXF3 NXT1 ORC1 PHAX PHB PKIA PXN RAN RANBP1 RANBP2 RANBP3 RCC1 RCN2 RGS14 RIC8A RPS6KB1 SERPINB1 SERTAD2 SIRT2 SMAD1 SMARCB1 SMURF1 SNUPN SOX2 STAT1 STRADA TERF2IP TERT TOP2A TOP2B TP73
Entrez ID 7153 7514
HPRD ID 00536 03975
Ensembl ID ENSG00000131747 ENSG00000082898
Uniprot IDs P11388 B3KWD0 O14980
PDB IDs 1LWZ 1ZXM 1ZXN 4FM9 1W9C 2L1L 3GB8 4BSM 4BSN
Enriched GO Terms of Interacting Partners?
Tagcloud ?
adjacent  adr  adriamycin  allelic  antineoplastic  chimeric  chromatin  close  decondensed  description  disruption  fibers  fish  fluorescence  fusion  hybridization  juxtaposition  metaphase  murine  proximity  rara  rearrangement  resistant  separate  situ  topoisomerase  transcript  truncated 
accounting  atm  bioinformatics  birc3  concordance  confirmation  conservative  cutoff  discordant  eventually  haloplex  hiseq  ighv  ighv3  klhl6  lymphocytic  myd88  next  notch1  pot1  precision  recurrently  repeating  reproducible  sanger  sequencing  sf3b1  stand  unmutated 
Tagcloud (Difference) ?
adjacent  adr  adriamycin  allelic  antineoplastic  chimeric  chromatin  close  decondensed  description  disruption  fibers  fish  fluorescence  fusion  hybridization  juxtaposition  metaphase  murine  proximity  rara  rearrangement  resistant  separate  situ  topoisomerase  transcript  truncated 
accounting  atm  bioinformatics  birc3  concordance  confirmation  conservative  cutoff  discordant  eventually  haloplex  hiseq  ighv  ighv3  klhl6  lymphocytic  myd88  next  notch1  pot1  precision  recurrently  repeating  reproducible  sanger  sequencing  sf3b1  stand  unmutated 
Tagcloud (Intersection) ?