TNNT3 and NUDT3

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		TNNT3	NUDT3
Gene Name		troponin T type 3 (skeletal, fast)	nudix (nucleoside diphosphate linked moiety X)-type motif 3
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Troponin Complex	Cytosol Extracellular Vesicular Exosome
	Molecular Function	Actin Binding Tropomyosin Binding Troponin C Binding Calcium-dependent ATPase Activity Troponin I Binding Calcium-dependent Protein Binding	Magnesium Ion Binding Diphosphoinositol-polyphosphate Diphosphatase Activity Inositol Diphosphate Tetrakisphosphate Diphosphatase Activity Inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate Diphosphatase Activity Inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate Diphosphatase Activity Inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate Diphosphatase Activity Inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase Activity Inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase Activity Inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase Activity
	Biological Process	Skeletal Muscle Contraction Regulation Of Striated Muscle Contraction Metabolic Process Muscle Filament Sliding Regulation Of ATPase Activity	Cell-cell Signaling Diadenosine Polyphosphate Catabolic Process Inositol Phosphate Metabolic Process Small Molecule Metabolic Process Diphosphoinositol Polyphosphate Catabolic Process
Pathways		Striated Muscle Contraction	Synthesis of pyrophosphates in the cytosol Inositol phosphate metabolism
Drugs
Diseases
GWAS			Body mass index ( 20935630) Height ( 19893584)
Protein-Protein Interactions		6 interactors: HAP1 NUDT3 SNUPN TNNI2 TRIM63 TSG101	36 interactors: ALAS1 APEX1 ARL6IP1 ASB13 CCL11 CHCHD3 DBN1 DDR1 DNAJA1 EEF1G FXYD3 HES1 ITFG1 MAF1 MCM5 MEX3B NR2C1 NUDT5 OAT PDCD5 PEX5 PRKD3 RAB17 REEP5 RNF126 RPL17 RPL8 RPLP1 SOX30 TNNT3 TUBA1A TUBGCP4 UBR1 VPS51 WDR74 XPNPEP1
Entrez ID		7140	11165
HPRD ID		02822	14849
Ensembl ID		ENSG00000130595
Uniprot IDs		P45378	O95989
PDB IDs			2FVV 2Q9P
Enriched GO Terms of Interacting Partners?		Diphosphoinositol Polyphosphate Catabolic Process SnRNA Import Into Nucleus Positive Regulation Of Neurotrophin Production Diadenosine Polyphosphate Catabolic Process Positive Regulation Of Nonmotile Primary Cilium Assembly Catabolic Process RNA Import Into Nucleus Regulation Of Exocytosis Regulation Of Organelle Transport Along Microtubule Positive Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Positive Regulation Of Cilium Assembly Cellular Macromolecule Catabolic Process Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation Muscle Contraction Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Regulation Of Extracellular Vesicular Exosome Assembly Skeletal Muscle Atrophy Striated Muscle Atrophy Muscle System Process Muscle Atrophy Viral Budding Hypothalamus Cell Differentiation Skeletal Muscle Adaptation Negative Regulation Of Beta-amyloid Formation Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Retrograde Axon Cargo Transport Viral Protein Processing Regulation Of Vesicle-mediated Transport Negative Regulation Of Amyloid Precursor Protein Catabolic Process Regulation Of Microtubule-based Movement Protein Transport Positive Regulation Of Synaptic Transmission, GABAergic Cellular Response To Organic Cyclic Compound Establishment Of Protein Localization Nucleotide-excision Repair, DNA Gap Filling Negative Regulation Of Smooth Muscle Cell Migration DNA Demethylation Intracellular Transport Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Telomere Maintenance Via Semi-conservative Replication Aromatic Compound Catabolic Process Regulation Of Beta-amyloid Formation Virion Assembly Regulation Of Cilium Assembly Nuclear DNA Replication Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Amyloid Precursor Protein Catabolic Process Telomere Maintenance Via Recombination Positive Regulation Of ERBB Signaling Pathway	Protein Targeting To Membrane Cotranslational Protein Targeting To Membrane Establishment Of Protein Localization To Membrane Cellular Metabolic Process Protein Targeting Intracellular Transport Protein Localization To Organelle Cellular Localization Cellular Protein Localization Translational Elongation Establishment Of Protein Localization To Organelle Catabolic Process Protein Localization To Membrane Protein Localization Intracellular Protein Transport Viral Transcription Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay SRP-dependent Cotranslational Protein Targeting To Membrane Cellular Process Establishment Of Localization In Cell Protein Targeting To ER Cytoplasmic Transport Aromatic Compound Catabolic Process Establishment Of Protein Localization To Endoplasmic Reticulum Protein Transport Protein Localization To Endoplasmic Reticulum DNA Strand Elongation Involved In DNA Replication Establishment Of Protein Localization Branching Involved In Mammary Gland Duct Morphogenesis DNA Strand Elongation Translational Termination Membrane Organization Cellular Macromolecule Catabolic Process Nuclear-transcribed MRNA Catabolic Process Metabolic Process MRNA Catabolic Process Transcription Factor TFIIIB Complex Assembly Negative Regulation Of Stomach Neuroendocrine Cell Differentiation Negative Regulation Of Pancreatic A Cell Differentiation Cytoplasm-associated Proteasomal Ubiquitin-dependent Protein Catabolic Process Pharyngeal Arch Artery Morphogenesis Lateral Inhibition Positive Regulation Of Protein Import Into Mitochondrial Outer Membrane Negative Regulation Of Chaperone-mediated Protein Folding Mammary Gland Duct Morphogenesis RNA Catabolic Process Cellular Nitrogen Compound Metabolic Process Response To Interleukin-4 Cellular Protein Complex Disassembly Viral Life Cycle
Tagcloud ?		11p15 2g7 biallelic biallelically bipaternal boundary clustered contiguous escape frames h19 homologue igf2 imprinted imprinting kb kip2 l23mrp lacks lies outline polyadenylated rodent spliced synteny troponin ubiquitously wilms wts
Tagcloud (Difference) ?		11p15 2g7 biallelic biallelically bipaternal boundary clustered contiguous escape frames h19 homologue igf2 imprinted imprinting kb kip2 l23mrp lacks lies outline polyadenylated rodent spliced synteny troponin ubiquitously wilms wts
Tagcloud (Intersection) ?