NUDT3 and CHCHD3

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		NUDT3	CHCHD3
Gene Name		nudix (nucleoside diphosphate linked moiety X)-type motif 3	coiled-coil-helix-coiled-coil-helix domain containing 3
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Extracellular Vesicular Exosome	Nucleus Cytoplasm Mitochondrion Mitochondrial Inner Membrane Extracellular Vesicular Exosome
	Molecular Function	Magnesium Ion Binding Diphosphoinositol-polyphosphate Diphosphatase Activity Inositol Diphosphate Tetrakisphosphate Diphosphatase Activity Inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate Diphosphatase Activity Inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate Diphosphatase Activity Inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate Diphosphatase Activity Inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase Activity Inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase Activity Inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase Activity	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Negative Regulation Of Transcription Protein Binding Phosphatase Binding Protein Complex Scaffold
	Biological Process	Cell-cell Signaling Diadenosine Polyphosphate Catabolic Process Inositol Phosphate Metabolic Process Small Molecule Metabolic Process Diphosphoinositol Polyphosphate Catabolic Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Inner Mitochondrial Membrane Organization Mitochondrial Fusion
Pathways		Synthesis of pyrophosphates in the cytosol Inositol phosphate metabolism
Drugs
Diseases
GWAS		Body mass index ( 20935630) Height ( 19893584)
Protein-Protein Interactions		36 interactors: ALAS1 APEX1 ARL6IP1 ASB13 CCL11 CHCHD3 DBN1 DDR1 DNAJA1 EEF1G FXYD3 HES1 ITFG1 MAF1 MCM5 MEX3B NR2C1 NUDT5 OAT PDCD5 PEX5 PRKD3 RAB17 REEP5 RNF126 RPL17 RPL8 RPLP1 SOX30 TNNT3 TUBA1A TUBGCP4 UBR1 VPS51 WDR74 XPNPEP1	22 interactors: BLZF1 CALCOCO2 CCDC33 CCDC85B FANCL GMCL1P1 GOLGA2 KRT40 KRTAP4-12 LZTS2 NOTCH2NL NUDT3 PDE4DIP RAB3IP RPGRIP1 SAMM50 SPAG5 SPERT SSX2IP TRAF1 TRIM27 USHBP1
Entrez ID		11165	54927
HPRD ID		14849	13044
Ensembl ID			ENSG00000106554
Uniprot IDs		O95989	A4D1N4 G3V1K1 Q9NX63
PDB IDs		2FVV 2Q9P
Enriched GO Terms of Interacting Partners?		Protein Targeting To Membrane Cotranslational Protein Targeting To Membrane Establishment Of Protein Localization To Membrane Cellular Metabolic Process Protein Targeting Intracellular Transport Protein Localization To Organelle Cellular Localization Cellular Protein Localization Translational Elongation Establishment Of Protein Localization To Organelle Catabolic Process Protein Localization To Membrane Protein Localization Intracellular Protein Transport Viral Transcription Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay SRP-dependent Cotranslational Protein Targeting To Membrane Cellular Process Establishment Of Localization In Cell Protein Targeting To ER Cytoplasmic Transport Aromatic Compound Catabolic Process Establishment Of Protein Localization To Endoplasmic Reticulum Protein Transport Protein Localization To Endoplasmic Reticulum DNA Strand Elongation Involved In DNA Replication Establishment Of Protein Localization Branching Involved In Mammary Gland Duct Morphogenesis DNA Strand Elongation Translational Termination Membrane Organization Cellular Macromolecule Catabolic Process Nuclear-transcribed MRNA Catabolic Process Metabolic Process MRNA Catabolic Process Transcription Factor TFIIIB Complex Assembly Negative Regulation Of Stomach Neuroendocrine Cell Differentiation Negative Regulation Of Pancreatic A Cell Differentiation Cytoplasm-associated Proteasomal Ubiquitin-dependent Protein Catabolic Process Pharyngeal Arch Artery Morphogenesis Lateral Inhibition Positive Regulation Of Protein Import Into Mitochondrial Outer Membrane Negative Regulation Of Chaperone-mediated Protein Folding Mammary Gland Duct Morphogenesis RNA Catabolic Process Cellular Nitrogen Compound Metabolic Process Response To Interleukin-4 Cellular Protein Complex Disassembly Viral Life Cycle	Golgi To Plasma Membrane Transport Intracellular Transport Establishment Of Protein Localization To Membrane Diphosphoinositol Polyphosphate Catabolic Process Diadenosine Polyphosphate Catabolic Process Cytoplasmic Transport Cellular Component Assembly Negative Regulation Of Interleukin-2 Secretion Mitotic Cell Cycle Post-Golgi Vesicle-mediated Transport Establishment Of Localization In Cell Protein Localization To Membrane
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