NUDT3 and RAB17

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		NUDT3	RAB17
Gene Name		nudix (nucleoside diphosphate linked moiety X)-type motif 3	RAB17, member RAS oncogene family
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Extracellular Vesicular Exosome	Intracellular Early Endosome Plasma Membrane Basolateral Plasma Membrane Apical Plasma Membrane Endocytic Vesicle Dendrite Melanosome Neuronal Cell Body Recycling Endosome Recycling Endosome Membrane Extracellular Vesicular Exosome
	Molecular Function	Magnesium Ion Binding Diphosphoinositol-polyphosphate Diphosphatase Activity Inositol Diphosphate Tetrakisphosphate Diphosphatase Activity Inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate Diphosphatase Activity Inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate Diphosphatase Activity Inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate Diphosphatase Activity Inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase Activity Inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase Activity Inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase Activity	GTPase Activity Protein Binding GTP Binding GDP Binding
	Biological Process	Cell-cell Signaling Diadenosine Polyphosphate Catabolic Process Inositol Phosphate Metabolic Process Small Molecule Metabolic Process Diphosphoinositol Polyphosphate Catabolic Process	Immunoglobulin Transcytosis In Epithelial Cells Mediated By Polymeric Immunoglobulin Receptor Intracellular Protein Transport Regulation Of Endocytosis Establishment Of Melanosome Localization Melanosome Transport Endocytic Recycling Rab Protein Signal Transduction Cilium Assembly Transcytosis Filopodium Assembly Regulation Of Dendrite Development Regulation Of Filopodium Assembly Regulation Of Synapse Assembly
Pathways		Synthesis of pyrophosphates in the cytosol Inositol phosphate metabolism
Drugs
Diseases
GWAS		Body mass index ( 20935630) Height ( 19893584)	Obesity-related traits ( 23251661)
Protein-Protein Interactions		36 interactors: ALAS1 APEX1 ARL6IP1 ASB13 CCL11 CHCHD3 DBN1 DDR1 DNAJA1 EEF1G FXYD3 HES1 ITFG1 MAF1 MCM5 MEX3B NR2C1 NUDT5 OAT PDCD5 PEX5 PRKD3 RAB17 REEP5 RNF126 RPL17 RPL8 RPLP1 SOX30 TNNT3 TUBA1A TUBGCP4 UBR1 VPS51 WDR74 XPNPEP1	9 interactors: ACVR1 C11orf49 FAM9B MAGEA1 NUDT3 RAB7A RABAC1 S100A8 SMURF2
Entrez ID		11165	64284
HPRD ID		14849	11468
Ensembl ID			ENSG00000124839
Uniprot IDs		O95989	Q6PJZ0 Q9H0T7
PDB IDs		2FVV 2Q9P
Enriched GO Terms of Interacting Partners?		Protein Targeting To Membrane Cotranslational Protein Targeting To Membrane Establishment Of Protein Localization To Membrane Cellular Metabolic Process Protein Targeting Intracellular Transport Protein Localization To Organelle Cellular Localization Cellular Protein Localization Translational Elongation Establishment Of Protein Localization To Organelle Catabolic Process Protein Localization To Membrane Protein Localization Intracellular Protein Transport Viral Transcription Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay SRP-dependent Cotranslational Protein Targeting To Membrane Cellular Process Establishment Of Localization In Cell Protein Targeting To ER Cytoplasmic Transport Aromatic Compound Catabolic Process Establishment Of Protein Localization To Endoplasmic Reticulum Protein Transport Protein Localization To Endoplasmic Reticulum DNA Strand Elongation Involved In DNA Replication Establishment Of Protein Localization Branching Involved In Mammary Gland Duct Morphogenesis DNA Strand Elongation Translational Termination Membrane Organization Cellular Macromolecule Catabolic Process Nuclear-transcribed MRNA Catabolic Process Metabolic Process MRNA Catabolic Process Transcription Factor TFIIIB Complex Assembly Negative Regulation Of Stomach Neuroendocrine Cell Differentiation Negative Regulation Of Pancreatic A Cell Differentiation Cytoplasm-associated Proteasomal Ubiquitin-dependent Protein Catabolic Process Pharyngeal Arch Artery Morphogenesis Lateral Inhibition Positive Regulation Of Protein Import Into Mitochondrial Outer Membrane Negative Regulation Of Chaperone-mediated Protein Folding Mammary Gland Duct Morphogenesis RNA Catabolic Process Cellular Nitrogen Compound Metabolic Process Response To Interleukin-4 Cellular Protein Complex Disassembly Viral Life Cycle	Negative Regulation Of Signal Transduction Negative Regulation Of Signaling Regulation Of Signal Transduction Acute Inflammatory Response BMP Signaling Pathway Regulation Of Signaling Diphosphoinositol Polyphosphate Catabolic Process Diadenosine Polyphosphate Catabolic Process Epidermal Growth Factor Catabolic Process Endocardial Cushion Cell Fate Commitment Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Catabolic Process Neutrophil Aggregation Transforming Growth Factor Beta Receptor Signaling Pathway Cellular Response To Transforming Growth Factor Beta Stimulus Response To Transforming Growth Factor Beta Phagosome-lysosome Fusion Sequestering Of Zinc Ion Phagosome Acidification Mitral Valve Morphogenesis Cardiac Muscle Cell Fate Commitment Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Mitral Valve Development Ubiquitin-dependent SMAD Protein Catabolic Process Protein To Membrane Docking Positive Regulation Of Determination Of Dorsal Identity Negative Regulation Of Activin Receptor Signaling Pathway Atrial Septum Primum Morphogenesis Chemokine Production Endocardial Cell Differentiation Sequestering Of Metal Ion Positive Regulation Of Signal Transduction Positive Regulation Of Secretion Septum Primum Development Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Protein Targeting To Lysosome Pathway-restricted SMAD Protein Phosphorylation Chronic Inflammatory Response Phagolysosome Assembly Protein Localization To Lysosome Cellular Zinc Ion Homeostasis Regulation Of Autophagic Vacuole Assembly Zinc Ion Homeostasis Leukocyte Migration Involved In Inflammatory Response Muscle Cell Fate Commitment Inflammatory Response Pharyngeal System Development Regulation Of Vacuole Organization Endocardium Development
Tagcloud ?			accessibility acclimation acetyl altogether catalyze cold deacetylases deacetylation demethylation drought hdacs histones hyperacetylation hypoacetylated ice1 maize methylated micrococcal mnase nuclease repressor responding stresses trichostatin tsa zmcor413 zmdbf1 zmdreb1 zmice1
Tagcloud (Difference) ?			accessibility acclimation acetyl altogether catalyze cold deacetylases deacetylation demethylation drought hdacs histones hyperacetylation hypoacetylated ice1 maize methylated micrococcal mnase nuclease repressor responding stresses trichostatin tsa zmcor413 zmdbf1 zmdreb1 zmice1
Tagcloud (Intersection) ?