TNNT3 and SNUPN

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		TNNT3	SNUPN
Description		troponin T3, fast skeletal type	snurportin 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Troponin Complex	Nucleus Nuclear Pore Nucleoplasm Cytoplasm Cytosol Plasma Membrane NLS-dependent Protein Nuclear Import Complex
	Molecular Function	Actin Binding Tropomyosin Binding Troponin C Binding Troponin I Binding Calcium-dependent Protein Binding	RNA Cap Binding RNA Binding Protein Binding Nuclear Import Signal Receptor Activity
	Biological Process	Skeletal Muscle Contraction Regulation Of Muscle Contraction Striated Muscle Contraction Regulation Of Striated Muscle Contraction Regulation Of ATP-dependent Activity Sarcomere Organization Positive Regulation Of Calcium-dependent ATPase Activity	RNA Import Into Nucleus Protein Import Into Nucleus Cytoskeleton Organization Protein Complex Oligomerization Protein Tetramerization SnRNA Import Into Nucleus
Pathways		Striated Muscle Contraction	snRNP Assembly
Drugs
Diseases		Distal arthrogryposis (DA)
GWAS		Appendicular lean mass ( 33097823) Celiac disease ( 23936387) Diastolic blood pressure ( 27618452) Diastolic blood pressure (cigarette smoking interaction) ( 29455858) Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) Hypertension ( 30487518) Mammographic density (dense area) ( 25342443) Mean arterial pressure ( 27618448 30487518) Pulse pressure x alcohol consumption interaction (2df test) ( 29912962) Systolic blood pressure ( 27618452) Systolic blood pressure (cigarette smoking interaction) ( 29455858) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858)	Appendicular lean mass ( 33097823) Hip circumference adjusted for BMI ( 34021172)
Interacting Genes		10 interacting genes: CLIP4 HAP1 NLGN3 NUDT3 SNUPN TNNI2 TRIM63 TSG101 TULP3 WASL	15 interacting genes: DBN1 DDX20 ENO2 GCNT3 KPNB1 MEX3B PAFAH1B2 PEX5 RNF126 RPL17 SMN1 SNRPB TNNT3 XPO1 ZPR1
Entrez ID		7140	10073
HPRD ID		02822	07441
Ensembl ID		ENSG00000130595	ENSG00000169371
Uniprot IDs		A0A286YFB1 A0A9L9PY19 H9KVA2 P45378	O95149
PDB IDs			1XK5 2P8Q 2Q5D 2QNA 3GB8 3GJX 3LWW 3NBY 3NBZ 3NC0 5DIS
Enriched GO Terms of Interacting Partners?		Vesicle Localization Establishment Of Vesicle Localization Nucleus Positive Regulation Of Cellular Component Biogenesis Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Establishment Of Organelle Localization Regulation Of ERBB Signaling Pathway Establishment Of Localization In Cell Positive Regulation Of Ubiquitin-dependent Endocytosis Positive Regulation Of Viral Budding Via Host ESCRT Complex Intraciliary Transport Particle A Binding Bronchus Morphogenesis Negative Regulation Of Membrane Tubulation Vesicle Cytoskeletal Trafficking Positive Regulation Of Clathrin-dependent Endocytosis Brain-derived Neurotrophic Factor Binding Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Positive Regulation Of Neurotrophin Production Positive Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity SnRNA Import Into Nucleus 5'-(N(7)-methyl 5'-triphosphoguanosine)-[mRNA] Diphosphatase Activity Inositol Diphosphate Tetrakisphosphate Diphosphatase Activity Diphosphoinositol Polyphosphate Metabolic Process Inositol Diphosphate Pentakisphosphate Diphosphatase Activity Inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase Activity Diphosphoinositol Polyphosphate Catabolic Process Bis(5'-adenosyl)-hexaphosphatase Activity Diadenosine Hexaphosphate Catabolic Process Inositol Phosphate Catabolic Process Diadenosine Pentaphosphate Catabolic Process Adenosine 5'-(hexahydrogen Pentaphosphate) Catabolic Process Diphosphoinositol-polyphosphate Diphosphatase Activity Endopolyphosphatase Activity Inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate Diphosphatase Activity Rhythmic Synaptic Transmission Symmetric, GABA-ergic, Inhibitory Synapse Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation Troponin T Binding Exosomal Secretion Organelle Localization Smoothened Signaling Pathway Involved In Dorsal/ventral Neural Tube Patterning Positive Regulation Of Plasma Membrane Bounded Cell Projection Assembly Actin Cap RNA Import Into Nucleus Bis(5'-adenosyl)-pentaphosphatase Activity Diadenosine Polyphosphate Catabolic Process Asymmetric, Glutamatergic, Excitatory Synapse Positive Regulation Of Cellular Component Organization Hypothalamus Cell Differentiation Skeletal Muscle Atrophy	Gemini Of Cajal Bodies SMN-Sm Protein Complex Growth Cone Spliceosomal SnRNP Assembly Cajal Body SMN Complex Cytoplasm Regulation Of Nucleocytoplasmic Transport Cerebral Cortex Neuron Differentiation Perikaryon Regulation Of Intracellular Protein Transport Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway RNA Splicing Cerebral Cortex Cell Migration Cytosol Negative Regulation Of ERBB Signaling Pathway Cell Cortex Positive Regulation Of Dendritic Spine Development Protein-containing Complex Forebrain Neuron Differentiation Positive Regulation Of Protein Import Into Nucleus MRNA Processing Telencephalon Cell Migration Forebrain Cell Migration Negative Regulation Of Core Promoter Binding Spliceosomal Complex Assembly Protein-RNA Complex Assembly Positive Regulation Of Calcium-dependent ATPase Activity DNA Endoreduplication Pre-mRNA Catabolic Process Acetylgalactosaminyl-O-glycosyl-glycoprotein Beta-1,6-N-acetylglucosaminyltransferase Activity Regulation Of Dendritic Spine Development Protein Domain Specific Binding Protein Monoubiquitination Cell Communication By Chemical Coupling Synaptic Membrane RNA Binding Nuclear Membrane Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Cajal-Retzius Cell Differentiation Regulation Of Protein Import Into Nucleus Positive Regulation Of Nucleocytoplasmic Transport Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of Intracellular Transport Peroxisome Membrane Targeting Sequence Binding Peroxisome Matrix Targeting Signal-1 Binding U2 SnRNP Binding Cellular Response To Triglyceride N-acetyllactosaminide Beta-1,6-N-acetylglucosaminyltransferase Activity Beta-1,3-galactosyl-O-glycosyl-glycoprotein Beta-1,6-N-acetylglucosaminyltransferase Activity
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