TNNT3 and TNNI2

Number of citations of the paper that reports this interaction (PMID 8987992)
4

Data Source:
HPRD (in vitro)

		TNNT3	TNNI2
Gene Name		troponin T type 3 (skeletal, fast)	troponin I type 2 (skeletal, fast)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Troponin Complex	Nucleus Cytosol Troponin Complex
	Molecular Function	Actin Binding Tropomyosin Binding Troponin C Binding Calcium-dependent ATPase Activity Troponin I Binding Calcium-dependent Protein Binding	Actin Binding Protein Binding Troponin T Binding
	Biological Process	Skeletal Muscle Contraction Regulation Of Striated Muscle Contraction Metabolic Process Muscle Filament Sliding Regulation Of ATPase Activity	Skeletal Muscle Contraction Regulation Of Muscle Contraction Muscle Filament Sliding Positive Regulation Of Transcription, DNA-templated
Pathways		Striated Muscle Contraction	Striated Muscle Contraction
Drugs
Diseases
GWAS			Inflammatory bowel disease ( 23128233)
Protein-Protein Interactions		6 interactors: HAP1 NUDT3 SNUPN TNNI2 TRIM63 TSG101	13 interactors: ACTB CALM1 ESRRA HNF4G PKD2L1 RORB TNNC1 TNNC2 TNNT1 TNNT3 TRIM55 TRIM63 UPF2
Entrez ID		7140	7136
HPRD ID		02822	01843
Ensembl ID		ENSG00000130595	ENSG00000130598
Uniprot IDs		P45378	P48788
PDB IDs
Enriched GO Terms of Interacting Partners?		Diphosphoinositol Polyphosphate Catabolic Process SnRNA Import Into Nucleus Positive Regulation Of Neurotrophin Production Diadenosine Polyphosphate Catabolic Process Positive Regulation Of Nonmotile Primary Cilium Assembly Catabolic Process RNA Import Into Nucleus Regulation Of Exocytosis Regulation Of Organelle Transport Along Microtubule Positive Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Positive Regulation Of Cilium Assembly Cellular Macromolecule Catabolic Process Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation Muscle Contraction Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Regulation Of Extracellular Vesicular Exosome Assembly Skeletal Muscle Atrophy Striated Muscle Atrophy Muscle System Process Muscle Atrophy Viral Budding Hypothalamus Cell Differentiation Skeletal Muscle Adaptation Negative Regulation Of Beta-amyloid Formation Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Retrograde Axon Cargo Transport Viral Protein Processing Regulation Of Vesicle-mediated Transport Negative Regulation Of Amyloid Precursor Protein Catabolic Process Regulation Of Microtubule-based Movement Protein Transport Positive Regulation Of Synaptic Transmission, GABAergic Cellular Response To Organic Cyclic Compound Establishment Of Protein Localization Nucleotide-excision Repair, DNA Gap Filling Negative Regulation Of Smooth Muscle Cell Migration DNA Demethylation Intracellular Transport Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Telomere Maintenance Via Semi-conservative Replication Aromatic Compound Catabolic Process Regulation Of Beta-amyloid Formation Virion Assembly Regulation Of Cilium Assembly Nuclear DNA Replication Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Amyloid Precursor Protein Catabolic Process Telomere Maintenance Via Recombination Positive Regulation Of ERBB Signaling Pathway	Muscle Contraction Skeletal Muscle Contraction Actin-myosin Filament Sliding Muscle Filament Sliding Muscle System Process Musculoskeletal Movement Actin-mediated Cell Contraction Regulation Of Muscle Contraction Actin Filament-based Movement Striated Muscle Contraction Cellular Response To Steroid Hormone Stimulus Response To Steroid Hormone Steroid Hormone Mediated Signaling Pathway Cellular Response To Organic Cyclic Compound Hormone-mediated Signaling Pathway Response To Lipid Cellular Response To Lipid Response To Organic Cyclic Compound Response To Hormone Transcription Initiation From RNA Polymerase II Promoter Intracellular Receptor Signaling Pathway Substantia Nigra Development Cellular Response To Hormone Stimulus Regulation Of ATPase Activity DNA-templated Transcription, Initiation Actin Filament-based Process Neural Nucleus Development Organ Development Regulation Of Muscle Filament Sliding Speed Movement Of Cell Or Subcellular Component Regulation Of Striated Muscle Contraction Midbrain Development Detection Of Chemical Stimulus Involved In Sensory Perception Of Sour Taste Regulation Of Systemic Arterial Blood Pressure By Ischemic Conditions Vascular Endothelial Growth Factor Receptor Signaling Pathway Regulation Of Muscle Filament Sliding Diaphragm Contraction Positive Regulation Of Cyclic-nucleotide Phosphodiesterase Activity Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation Regulation Of Osteoblast Differentiation Cellular Response To Organic Substance Signal Transduction Amacrine Cell Differentiation Regulation Of High Voltage-gated Calcium Channel Activity Sensory Perception Of Sour Taste Involuntary Skeletal Muscle Contraction System Development Skeletal Muscle Atrophy Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Response To Glucocorticoid
Tagcloud ?		11p15 2g7 biallelic biallelically bipaternal boundary clustered contiguous escape frames h19 homologue igf2 imprinted imprinting kb kip2 l23mrp lacks lies outline polyadenylated rodent spliced synteny troponin ubiquitously wilms wts
Tagcloud (Difference) ?		11p15 2g7 biallelic biallelically bipaternal boundary clustered contiguous escape frames h19 homologue igf2 imprinted imprinting kb kip2 l23mrp lacks lies outline polyadenylated rodent spliced synteny troponin ubiquitously wilms wts
Tagcloud (Intersection) ?