RPS6KA6 and CENPB

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		RPS6KA6	CENPB
Gene Name		ribosomal protein S6 kinase, 90kDa, polypeptide 6	centromere protein B, 80kDa
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Mitochondrion Cytosol	Chromosome, Centromeric Region Nucleus Chromosome
	Molecular Function	Magnesium Ion Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity ATP Binding	Chromatin Binding Satellite DNA Binding Centromeric DNA Binding Sequence-specific DNA Binding
	Biological Process	Protein Phosphorylation DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator Signal Transduction Synaptic Transmission Axon Guidance Central Nervous System Development Negative Regulation Of Embryonic Development Negative Regulation Of ERK1 And ERK2 Cascade Negative Regulation Of Mesoderm Development	Regulation Of Transcription, DNA-templated
Pathways		Axon guidance RSK activation Activation of NMDA receptor upon glutamate binding and postsynaptic events L1CAM interactions Recycling pathway of L1 CREB phosphorylation through the activation of Ras Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell Transmission across Chemical Synapses Post NMDA receptor activation events
Drugs
Diseases
GWAS
Protein-Protein Interactions		28 interactors: ADIRF APP C14orf1 CEBPZ CENPB CLEC3B DHX34 DNAJC13 DNMT1 FBN3 FZD5 LMO4 MAPK3 MASP1 MED24 MICAL1 MPP1 NR4A1 RBPJ RPLP1 RXRA SAP30BP SPTBN4 SYNE4 UBE2I UFM1 ZNF227 ZNF746	17 interactors: ANXA7 APP CDKN1A CSNK2B FBXO25 GADD45A GFI1B GSK3B HAND2 NR3C1 PARP1 PARP2 PIN1 RPS6KA6 SMN1 TAC1 TK1
Entrez ID		27330	1059
HPRD ID		02250	00314
Ensembl ID			ENSG00000125817
Uniprot IDs		Q9UK32	P07199
PDB IDs			1BW6 1HLV 1UFI
Enriched GO Terms of Interacting Partners?		Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter RNA Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of RNA Metabolic Process RNA Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Gene Expression Regulation Of Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Transcription, DNA-templated Positive Regulation Of Metabolic Process Nucleobase-containing Compound Metabolic Process DNA-templated Transcription, Initiation Positive Regulation Of Cellular Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Gene Expression Cellular Nitrogen Compound Metabolic Process Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Cellular Macromolecule Biosynthetic Process Nitrogen Compound Metabolic Process Macromolecule Biosynthetic Process Intracellular Receptor Signaling Pathway Regulation Of Protein Metabolic Process Regulation Of Protein Processing Regulation Of Early Endosome To Late Endosome Transport Cell Differentiation Biosynthetic Process Cardiac Ventricle Development Negative Regulation Of Cellular Metabolic Process Labyrinthine Layer Blood Vessel Development Sterol Metabolic Process Tissue Development Cardiac Chamber Development Neuron Maturation Regulation Of Cell Fate Commitment Apoptotic Process Cell Maturation Negative Regulation Of Protein Processing Regulation Of Cellular Process Tissue Morphogenesis Programmed Cell Death Placenta Blood Vessel Development	Regulation Of Binding Negative Regulation Of Phosphorylation Regulation Of Signaling Anatomical Structure Development Cellular Metabolic Process Response To External Stimulus Positive Regulation Of Transcription Regulatory Region DNA Binding Regulation Of Phosphorylation Response To Organic Substance System Development Positive Regulation Of Cellular Metabolic Process Response To Stress Regulation Of DNA Binding Response To Hormone Apoptotic Process Regulation Of Signal Transduction Regulation Of Phosphorus Metabolic Process Signal Transduction In Response To DNA Damage Negative Regulation Of Cellular Metabolic Process Developmental Process Behavior Programmed Cell Death Cell Death Death Regulation Of Protein Phosphorylation Response To Abiotic Stimulus Multicellular Organismal Development Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Binding Tube Development Positive Regulation Of Protein Phosphorylation Suckling Behavior Regulation Of Protein Kinase Activity Cellular Protein Modification Process Regulation Of Transcription Regulatory Region DNA Binding Positive Regulation Of Protein Metabolic Process Axon Guidance Protein ADP-ribosylation Regulation Of Kinase Activity Response To Glucocorticoid Signal Transduction Negative Regulation Of MAPK Cascade Positive Regulation Of Metabolic Process Response To Corticosteroid Regulation Of Cellular Protein Metabolic Process Regulation Of Protein Import Into Nucleus Cellular Response To DNA Damage Stimulus Positive Regulation Of Phosphorylation Response To Organic Cyclic Compound Response To Inorganic Substance
Tagcloud ?		anchorage anticipated attribution azacytidine cdna chemoresponse clines codons deleted demethylation depended duplet encompass exclude exon immunoblots indolocarbazole isoforms nt nucleotides penultimate rsk4 situation sparse splice starvation suppressive triplet uncharacterized	agreement altman asian bland cenpa cohen fibrillarin iif immunoassay interstitial kappa ku lia limits nc ncs nor90 oa outside plots pmscl100 ro52 ro60 rp155 sle ssc stored telangiectasia utility
Tagcloud (Difference) ?		anchorage anticipated attribution azacytidine cdna chemoresponse clines codons deleted demethylation depended duplet encompass exclude exon immunoblots indolocarbazole isoforms nt nucleotides penultimate rsk4 situation sparse splice starvation suppressive triplet uncharacterized	agreement altman asian bland cenpa cohen fibrillarin iif immunoassay interstitial kappa ku lia limits nc ncs nor90 oa outside plots pmscl100 ro52 ro60 rp155 sle ssc stored telangiectasia utility
Tagcloud (Intersection) ?