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RPS6KA6 and MASP1
Number of citations of the paper that reports this interaction (PubMedID
21900206
)
0
Data Source:
BioGRID
(two hybrid)
RPS6KA6
MASP1
Description
ribosomal protein S6 kinase A6
MBL associated serine protease 1
Image
GO Annotations
Cellular Component
Fibrillar Center
Nucleus
Nucleoplasm
Nucleolus
Cytoplasm
Mitochondrion
Cytosol
Extracellular Region
Extracellular Space
Nucleoplasm
Cytosol
Symbiont Cell Surface
Molecular Function
Nucleotide Binding
Magnesium Ion Binding
Protein Kinase Activity
Protein Serine/threonine Kinase Activity
Ribosomal Protein S6 Kinase Activity
Protein Binding
ATP Binding
Kinase Activity
Transferase Activity
Metal Ion Binding
Protein Serine Kinase Activity
Serine-type Endopeptidase Activity
Calcium Ion Binding
Protein Binding
Peptidase Activity
Serine-type Peptidase Activity
Hydrolase Activity
Identical Protein Binding
Protein Homodimerization Activity
Metal Ion Binding
Calcium-dependent Protein Binding
Biological Process
Signal Transduction
Central Nervous System Development
DNA Damage Response, Signal Transduction By P53 Class Mediator
Intracellular Signal Transduction
TORC1 Signaling
Negative Regulation Of Embryonic Development
Negative Regulation Of ERK1 And ERK2 Cascade
Negative Regulation Of Mesoderm Development
Complement Activation, Lectin Pathway
Activation Of Membrane Attack Complex
Immune System Process
Proteolysis
Complement Activation
Complement Activation, Alternative Pathway
Opsonization
Zymogen Activation
Killing Of Cells Of Another Organism
Innate Immune Response
Negative Regulation Of Complement Activation
Protein Maturation
Pathways
Recycling pathway of L1
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling
RSK activation
RSK activation
Lectin pathway of complement activation
Initial triggering of complement
Ficolins bind to repetitive carbohydrate structures on the target cell surface
Scavenging by Class A Receptors
SARS-CoV-2 activates/modulates innate and adaptive immune responses
Drugs
Fostamatinib
Diseases
GWAS
Amyotrophic lateral sclerosis (sporadic) (
24529757
)
Blood protein levels (
30072576
)
Impulsivity (attentional) (
30718321
)
Type 2 diabetes (
30130595
)
Interacting Genes
28 interacting genes:
ADIRF
APP
CEBPZ
CENPB
CLEC3B
DHX34
DNAJC13
DNMT1
ERG28
FBN3
FZD5
LMO4
MASP1
MED24
MICAL1
MPP1
NR4A1
RBPJ
RPLP1
RXRA
SAP30BP
SPRED2
SPTBN4
SYNE4
UBE2I
UFM1
ZNF227
ZNF746
16 interacting genes:
C2
C3
FCN2
GADD45A
GSK3B
H2AX
MAPK6
MAPK8IP2
MAPT
MBL2
NCK2
NUDT21
RPS6KA3
RPS6KA6
SERPING1
UFD1
Entrez ID
27330
5648
HPRD ID
02250
02749
Ensembl ID
ENSG00000072133
ENSG00000127241
Uniprot IDs
A0AAU7BMN7
A0AAU7BMR9
A0AAU7BMT2
A0AAU7BN28
Q9UK32
P48740
PDB IDs
6G76
6G77
6G78
3DEM
3GOV
4AQB
4DJZ
4IGD
4IW4
4KKD
7PQO
Enriched GO Terms of Interacting Partners
?
Positive Regulation Of Transcription By RNA Polymerase II
Regulation Of RNA Metabolic Process
Regulation Of DNA-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of Transcription By RNA Polymerase II
Positive Regulation Of Biosynthetic Process
Positive Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of RNA Biosynthetic Process
Regulation Of Nucleobase-containing Compound Metabolic Process
Positive Regulation Of DNA-templated Transcription
Nuclear Vitamin D Receptor Binding
Developmental Maturation
Positive Regulation Of RNA Metabolic Process
Labyrinthine Layer Blood Vessel Development
Complement Activation, Lectin Pathway
Activation Of Membrane Attack Complex
Opsonization
Symbiont Cell Surface
Complement Activation
Positive Regulation Of Phagocytosis
Response To Stress
Regulation Of Phagocytosis
Classical-complement-pathway C3/C5 Convertase Complex
Complement Activation, Classical Pathway
Killing Of Cells Of Another Organism
Regulation Of Immune Response
Positive Regulation Of Endocytosis
Ribosomal Protein S6 Kinase Activity
Cell Killing
Positive Regulation Of Apoptotic Cell Clearance
Positive Regulation Of Opsonization
Signal Complex Assembly
Activation Of Immune Response
Regulation Of Immune System Process
Positive Regulation Of Cellular Component Organization
Regulation Of Apoptotic Cell Clearance
Regulation Of Opsonization
Serine-type Endopeptidase Complex
Regulation Of Innate Immune Response
Protein Kinase Binding
Complement Activation, GZMK Pathway
TOR Signaling
Regulation Of Defense Response
Humoral Immune Response
Regulation Of Cellular Response To Heat
Dynactin Binding
Regulation Of Cellular Response To Stress
Regulation Of Endocytosis
Protein Maturation
Blood Microparticle
Regulation Of Translation In Response To Stress
Regulation Of Complement Activation
Positive Regulation Of Immune System Process
Positive Regulation Of Immune Response
Signal Transduction
Immune Response-activating Signaling Pathway
Protein Serine Kinase Activity
Cellular Response To Stress
Signal Transduction In Response To DNA Damage
Immune Effector Process
Protein Metabolic Process
Protein Serine/threonine Kinase Activity
Response To Bacterium
Regulation Of Multicellular Organismal Process
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Tagcloud (Difference)
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Tagcloud (Intersection)
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