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RPS6KA6 and MICAL1
Number of citations of the paper that reports this interaction (PMID
21900206
)
27
Data Source:
BioGRID
(two hybrid)
RPS6KA6
MICAL1
Gene Name
ribosomal protein S6 kinase, 90kDa, polypeptide 6
microtubule associated monooxygenase, calponin and LIM domain containing 1
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
Nucleolus
Mitochondrion
Cytosol
Cytoplasm
Intermediate Filament
Molecular Function
Magnesium Ion Binding
Protein Kinase Activity
Protein Serine/threonine Kinase Activity
ATP Binding
Actin Binding
Protein Binding
Zinc Ion Binding
Oxidoreductase Activity, Acting On Paired Donors, With Incorporation Or Reduction Of Molecular Oxygen, NAD(P)H As One Donor, And Incorporation Of One Atom Of Oxygen
SH3 Domain Binding
Rab GTPase Binding
FAD Binding
Biological Process
Protein Phosphorylation
DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator
Signal Transduction
Synaptic Transmission
Axon Guidance
Central Nervous System Development
Negative Regulation Of Embryonic Development
Negative Regulation Of ERK1 And ERK2 Cascade
Negative Regulation Of Mesoderm Development
Negative Regulation Of Protein Phosphorylation
Cytoskeleton Organization
Signal Transduction
Sulfur Oxidation
Actin Filament Depolymerization
Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Oxidation-reduction Process
Pathways
Axon guidance
RSK activation
Activation of NMDA receptor upon glutamate binding and postsynaptic events
L1CAM interactions
Recycling pathway of L1
CREB phosphorylation through the activation of Ras
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
Transmission across Chemical Synapses
Post NMDA receptor activation events
Drugs
Diseases
GWAS
Protein-Protein Interactions
28 interactors:
ADIRF
APP
C14orf1
CEBPZ
CENPB
CLEC3B
DHX34
DNAJC13
DNMT1
FBN3
FZD5
LMO4
MAPK3
MASP1
MED24
MICAL1
MPP1
NR4A1
RBPJ
RPLP1
RXRA
SAP30BP
SPTBN4
SYNE4
UBE2I
UFM1
ZNF227
ZNF746
16 interactors:
ABL1
CRK
EHD1
GADD45A
GRB2
GSK3B
NEDD9
PIK3R3
PTK2
RAB10
RAB1A
RAB1B
RPS6KA6
SRC
TAB1
VIM
Entrez ID
27330
64780
HPRD ID
02250
06183
Ensembl ID
ENSG00000135596
Uniprot IDs
Q9UK32
Q8TDZ2
PDB IDs
1WYL
2CO8
2DK9
Enriched GO Terms of Interacting Partners
?
Regulation Of Transcription From RNA Polymerase II Promoter
Positive Regulation Of Gene Expression
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription From RNA Polymerase II Promoter
RNA Metabolic Process
Positive Regulation Of Macromolecule Biosynthetic Process
Regulation Of Nitrogen Compound Metabolic Process
Regulation Of RNA Metabolic Process
RNA Biosynthetic Process
Positive Regulation Of Cellular Biosynthetic Process
Gene Expression
Regulation Of Metabolic Process
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Transcription, DNA-templated
Positive Regulation Of Metabolic Process
Nucleobase-containing Compound Metabolic Process
DNA-templated Transcription, Initiation
Positive Regulation Of Cellular Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Regulation Of Gene Expression
Cellular Nitrogen Compound Metabolic Process
Transcription From RNA Polymerase II Promoter
Transcription Initiation From RNA Polymerase II Promoter
Cellular Macromolecule Biosynthetic Process
Nitrogen Compound Metabolic Process
Macromolecule Biosynthetic Process
Intracellular Receptor Signaling Pathway
Regulation Of Protein Metabolic Process
Regulation Of Protein Processing
Regulation Of Early Endosome To Late Endosome Transport
Cell Differentiation
Biosynthetic Process
Cardiac Ventricle Development
Negative Regulation Of Cellular Metabolic Process
Labyrinthine Layer Blood Vessel Development
Sterol Metabolic Process
Tissue Development
Cardiac Chamber Development
Neuron Maturation
Regulation Of Cell Fate Commitment
Apoptotic Process
Cell Maturation
Negative Regulation Of Protein Processing
Regulation Of Cellular Process
Tissue Morphogenesis
Programmed Cell Death
Placenta Blood Vessel Development
Fc Receptor Signaling Pathway
Enzyme Linked Receptor Protein Signaling Pathway
Cellular Response To Stimulus
Regulation Of Phosphorylation
Signal Transduction
Regulation Of MAPK Cascade
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Regulation Of Phosphorus Metabolic Process
Signaling
Cell Morphogenesis Involved In Differentiation
Cell Communication
Immune Response-regulating Signaling Pathway
Cellular Response To Organonitrogen Compound
Regulation Of Kinase Activity
Neuron Projection Development
Positive Regulation Of Protein Metabolic Process
Axonogenesis
Cell Development
Cellular Response To Peptide Hormone Stimulus
Axon Development
Cellular Response To Growth Factor Stimulus
Response To Stimulus
Cellular Response To Peptide
Intracellular Signal Transduction
Cell Morphogenesis Involved In Neuron Differentiation
Cellular Response To Organic Substance
Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
Fc-gamma Receptor Signaling Pathway
Fc Receptor Mediated Stimulatory Signaling Pathway
Response To Growth Factor
Neuron Development
Epidermal Growth Factor Receptor Signaling Pathway
ERBB Signaling Pathway
Vesicle-mediated Transport
Neuron Projection Morphogenesis
Endocytosis
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Axon Guidance
Cell Morphogenesis
Generation Of Neurons
Positive Regulation Of Protein Phosphorylation
Neuron Differentiation
Blood Coagulation
Cellular Response To Insulin Stimulus
Hemostasis
Regulation Of Protein Kinase Activity
Ras Protein Signal Transduction
Cell Projection Organization
Neurogenesis
Response To Peptide Hormone
Tagcloud
?
anchorage
anticipated
attribution
azacytidine
cdna
chemoresponse
clines
codons
deleted
demethylation
depended
duplet
encompass
exclude
exon
immunoblots
indolocarbazole
isoforms
nt
nucleotides
penultimate
rsk4
situation
sparse
splice
starvation
suppressive
triplet
uncharacterized
Tagcloud (Difference)
?
anchorage
anticipated
attribution
azacytidine
cdna
chemoresponse
clines
codons
deleted
demethylation
depended
duplet
encompass
exclude
exon
immunoblots
indolocarbazole
isoforms
nt
nucleotides
penultimate
rsk4
situation
sparse
splice
starvation
suppressive
triplet
uncharacterized
Tagcloud (Intersection)
?