TMPO and WEE2-AS1

Number of citations of the paper that reports this interaction (PubMedID 36123327)
40

Data Source:
BioGRID (unspecified method)

		TMPO	WEE2-AS1
Description		thymopoietin	WEE2 antisense RNA 1
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nuclear Envelope Nuclear Inner Membrane Chromosome Cytoplasm Membrane Nuclear Membrane	U1 SnRNP
	Molecular Function	DNA Binding Protein Binding Lamin Binding Cadherin Binding	Pre-mRNA 5'-splice Site Binding
	Biological Process		MRNA 5'-splice Site Recognition
Pathways		RHOA GTPase cycle RHOC GTPase cycle CDC42 GTPase cycle RAC1 GTPase cycle RAC2 GTPase cycle RHOD GTPase cycle RHOG GTPase cycle RHOJ GTPase cycle RAC3 GTPase cycle RHOF GTPase cycle
Drugs
Diseases
GWAS		Metabolite levels ( 23823483)
Interacting Genes		27 interacting genes: ABL1 AKAP8L BANF1 CDK1 CEBPA CLK1 CSNK2A1 FXR1 GMCL1 GOLM1 HDAC3 KLHL6 LMNA LMNB1 LMNB2 OGT OIP5 RB1 RNF123 SGTA SGTB SRC SRPK2 STOM SUMO2 USP7 WEE2-AS1	161 interacting genes: AASS ACSL3 ACTG1 AGAP1 AHNAK AJUBA AKAP11 ALB ALKBH4 ANXA2 ARL6IP4 ASPSCR1 ATAD3A BCLAF1 BRAT1 CALML5 CLPB COPB2 COPG1 CSTF1 CTNND1 CTU2 DAXX DDX1 DDX23 DIDO1 DLST DNAAF5 DOHH DPYSL4 DSC1 DSP EEF1A1 EGR2 EIF3A ELL EMD EPM2AIP1 ERAP1 ERH EXOC4 FAM120B FAM83H FLG FLG2 FMR1 FOXK1 FXR1 FXR2 GAB1 GAPDH GBF1 GNL3 GRB10 GSDME GSN GTF3C1 GTPBP1 GTSE1 HARS1 HAX1 HMGA1 HMGCS1 HNRNPA2B1 HNRNPC HNRNPH1 HNRNPH2 HNRNPLL HNRNPM HSP90AA1 HSP90AB1 HSPA6 HSPA8 HSPB1 IFIT1 IGF2BP1 IGF2BP3 KCTD3 KIF20A KIF22 LAMC1 LARP7 LDLR LUC7L2 MAGED2 MAP1A MED23 MINDY3 MOB1A MSH6 MYH9 MYO1C NCKAP1 NDFIP1 NEK9 NISCH NPM1 NUP160 NXF1 PABPC1 PALS2 PARP1 PCMT1 PDCD2L PDXP PIGU PJA2 PLEC POP1 PPL PPM1F PRKAR2A PSMB1 PSMD1 PTK2 QTRT2 RAB5A RAF1 RETREG2 RPL13 RPLP2 RPN2 RPP30 RPRD1B RPS17 RPS2 RPS28 RPS29 RPS8 S100A14 S100A7 SEC13 SERBP1 SHKBP1 SHTN1 SKIC2 SLC25A11 SLC27A3 SNX8 SQSTM1 SRP68 STAT5B TANK THBS1 THRAP3 TIMELESS TMPO TOR1AIP2 TPR TRIM21 TRIM56 TRMT10C TTC28 TUBA1B TUBB3 TUBB4B U2AF1 UBB USP1 XRCC6 YBX1
Entrez ID		7112	285962
HPRD ID		01777	08286
Ensembl ID		ENSG00000120802	ENSG00000228775
Uniprot IDs		G5E972 P42166 P42167 Q59G12
PDB IDs		1GJJ 1H9E 1H9F 8FN7 8FND 8FNG 8FNH 8FNJ 8FNL 8FNM 8FNN 8FNO 8FNP 8FNQ
Enriched GO Terms of Interacting Partners?		Nuclear Pore Localization Nucleus Organization Negative Regulation Of Gene Expression, Epigenetic Organelle Organization Chromatin Organization Nuclear Envelope Organization Negative Regulation Of Gene Expression Heterochromatin Formation Negative Regulation Of Macromolecule Metabolic Process Epigenetic Regulation Of Gene Expression Regulation Of Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Metabolic Process Chromatin Remodeling Regulation Of Proteasomal Protein Catabolic Process PML Body Nuclear Lamina Negative Regulation Of Macromolecule Biosynthetic Process Protein Localization To Nuclear Envelope Negative Regulation Of Biosynthetic Process Nuclear Matrix Regulation Of Proteolysis Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Structural Constituent Of Nuclear Lamina TRC Complex Negative Regulation Of Proteasomal Protein Catabolic Process Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Protein-containing Complex Localization Regulation Of Gene Expression Protein Localization To Organelle Regulation Of Macromolecule Biosynthetic Process Regulation Of Metabolic Process Symbiont-mediated Disruption Of Host Cell PML Body Negative Regulation Of Proteolysis Involved In Protein Catabolic Process Regulation Of Macromolecule Metabolic Process Regulation Of Protein Metabolic Process Positive Regulation Of Metabolic Process Nuclear Migration Regulation Of Cellular Localization Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of Proteolysis Nucleus Localization Cellular Response To Fluid Shear Stress Nucleus Regulation Of Protein Catabolic Process Positive Regulation Of Catabolic Process Nuclear Envelope Rb-E2F Complex Lamin Filament Positive Regulation Of Protein Metabolic Process Negative Regulation Of Protein Metabolic Process	RNA Binding Cytosol Ribonucleoprotein Complex Cytoplasm Nucleus Focal Adhesion Extracellular Exosome Nucleobase-containing Compound Metabolic Process Macromolecule Metabolic Process Nucleic Acid Metabolic Process RNA Metabolic Process Regulation Of Protein Metabolic Process Cytoplasmic Stress Granule MRNA Binding N6-methyladenosine-containing RNA Reader Activity Protein Binding MRNA Processing RNA Transport Nucleolus MRNA Transport Biological_process RNA Processing Nucleic Acid Binding Cellular Response To Heat Translation Regulator Activity Positive Regulation Of Protein Metabolic Process Nucleoplasm Positive Regulation Of Metabolic Process Regulation Of Translation At Presynapse, Modulating Synaptic Transmission Cornified Envelope Positive Regulation Of Macromolecule Metabolic Process MRNA Metabolic Process Positive Regulation Of Biosynthetic Process Response To Heat Regulation Of Translation Regulation Of MRNA Stability CRD-mediated MRNA Stabilization Ficolin-1-rich Granule Lumen MRNA 3'-UTR Binding Nucleobase-containing Compound Transport Regulation Of RNA Stability Negative Regulation Of MRNA Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Ubiquitin Protein Ligase Binding Structural Molecule Activity Positive Regulation Of Gene Expression RNA Splicing Cadherin Binding Negative Regulation Of MRNA Catabolic Process Regulation Of Plasma Membrane Organization
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