TMPO and LMNA

Number of citations of the paper that reports this interaction (PMID 12475961)
41

Data Source:
HPRD (in vivo)

		TMPO	LMNA
Gene Name		thymopoietin	lamin A/C
Image
Gene Ontology Annotations	Cellular Component	Chromatin Nucleus Nuclear Envelope Nuclear Inner Membrane Cytoplasm Membrane Integral Component Of Membrane Nuclear Membrane	Nucleus Nuclear Envelope Lamin Filament Nuclear Lamina Nucleoplasm Cytoplasm Cytosol Intermediate Filament Nuclear Speck Perinuclear Region Of Cytoplasm
	Molecular Function	DNA Binding Protein Binding Lamin Binding	Structural Molecule Activity Protein Binding
	Biological Process	Regulation Of Transcription, DNA-templated	Mitotic Cell Cycle Apoptotic Process Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Activation Of Signaling Protein Activity Involved In Unfolded Protein Response Mitotic Nuclear Envelope Disassembly Mitotic Nuclear Envelope Reassembly Muscle Organ Development Regulation Of Cell Migration Establishment Or Maintenance Of Microtubule Cytoskeleton Polarity Endoplasmic Reticulum Unfolded Protein Response Protein Localization To Nucleus Sterol Regulatory Element Binding Protein Import Into Nucleus Cellular Protein Metabolic Process Ventricular Cardiac Muscle Cell Development Cellular Response To Hypoxia Negative Regulation Of Release Of Cytochrome C From Mitochondria Positive Regulation Of Cell Aging Regulation Of Protein Localization To Nucleus Negative Regulation Of Extrinsic Apoptotic Signaling Pathway
Pathways			IRE1alpha activates chaperones XBP1(S) activates chaperone genes Unfolded Protein Response (UPR)
Drugs
Diseases
GWAS
Protein-Protein Interactions		13 interactors: AKAP8L BANF1 CSNK2A1 GMCL1 HDAC3 LMNA LMNB1 LMNB2 OIP5 RB1 SGTA SGTB USP7	43 interactors: ACTB ALOX12 ALOX12B CASP1 CASP6 CDK1 DBNL DUSP13 EGF EMD FLNA FOS GZMA GZMB KAT5 KRTAP10-3 KRTAP10-7 LMNB1 MLIP MRPS26 NARF PCBP1 PCGF2 PRKCA RB1 RBBP4 SH3KBP1 SMAD3 SREBF1 STAC SUMO4 SVIL SYNE1 TMPO TOR1A TOR1AIP1 UBE2I UCHL5 UNC13D URB2 VAV1 YWHAQ ZNF239
Entrez ID		7112	4000
HPRD ID		01777	01035
Ensembl ID		ENSG00000120802	ENSG00000160789
Uniprot IDs		G5E972 P42166 P42167 Q59G12	P02545
PDB IDs		1GJJ 1H9E 1H9F	1IFR 1IVT 1X8Y 2XV5 2YPT 3GEF 3V4Q 3V4W 3V5B
Enriched GO Terms of Interacting Partners?		Cell Cycle Process Mitotic Nuclear Envelope Reassembly Mitotic Cell Cycle Process Nuclear Envelope Reassembly Mitotic Cell Cycle Cell Cycle Regulation Of Proteasomal Protein Catabolic Process Viral Process Mitotic Nuclear Envelope Disassembly Chromatin Modification Nuclear Envelope Disassembly Regulation Of Mitotic Sister Chromatid Separation Regulation Of Mitotic Metaphase/anaphase Transition Chromatin Organization Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Nuclear Envelope Organization Sterol Regulatory Element Binding Protein Import Into Nucleus Execution Phase Of Apoptosis Regulation Of Chromosome Segregation Regulation Of Protein Catabolic Process Regulation Of Mitotic Cell Cycle Negative Regulation Of Transcription From RNA Polymerase II Promoter During Mitosis Sister Chromatid Biorientation Apoptotic Process Programmed Cell Death Chromosome Organization Microtubule Cytoskeleton Organization Negative Regulation Of Cell Cycle Cell Death Death Regulation Of Centromere Complex Assembly Negative Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle Establishment Or Maintenance Of Microtubule Cytoskeleton Polarity Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Nucleus Organization Regulation Of Mitotic Nuclear Division Regulation Of Cellular Protein Metabolic Process Maintenance Of Mitotic Sister Chromatid Cohesion Regulation Of Cohesin Localization To Chromatin Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Organelle Organization Negative Regulation Of Mitotic Cell Cycle Phase Transition Attachment Of Mitotic Spindle Microtubules To Kinetochore Positive Regulation Of Protein Metabolic Process Regulation Of Protein Metabolic Process Mitotic Cell Cycle Checkpoint Chromatin Remodeling Positive Regulation Of Mitotic Metaphase/anaphase Transition Maintenance Of DNA Methylation Glial Cell Apoptotic Process	Apoptotic Process Programmed Cell Death Cell Death Death Regulation Of Protein Localization Regulation Of Cellular Localization Positive Regulation Of Transport Nucleus Organization Nuclear Envelope Organization Regulation Of Signaling Regulation Of Establishment Of Protein Localization Positive Regulation Of Intracellular Transport Regulation Of Intracellular Transport Regulation Of Signal Transduction Organelle Organization Positive Regulation Of Nucleocytoplasmic Transport Enzyme Linked Receptor Protein Signaling Pathway Response To Stress Cellular Response To Growth Factor Stimulus Positive Regulation Of Signal Transduction Response To Growth Factor Immune Response Cellular Response To Organic Substance Positive Regulation Of Intracellular Protein Transport Regulation Of Protein Transport Regulation Of Catenin Import Into Nucleus Epidermal Growth Factor Receptor Signaling Pathway Execution Phase Of Apoptosis ERBB Signaling Pathway Positive Regulation Of Proteolysis Regulation Of Protein Import Into Nucleus Positive Regulation Of Cellular Protein Metabolic Process Organ Development Cellular Response To Stimulus Response To Wounding Platelet Activation Regulation Of Protein Localization To Nucleus Positive Regulation Of Protein Transport Positive Regulation Of Protein Import Into Nucleus Positive Regulation Of Protein Metabolic Process Vascular Endothelial Growth Factor Receptor Signaling Pathway Anatomical Structure Development Regulation Of Nucleocytoplasmic Transport Immune System Process Nuclear Membrane Organization Mitotic Nuclear Envelope Disassembly Intracellular Signal Transduction Positive Regulation Of Protein Localization To Nucleus Hepoxilin Metabolic Process Hepoxilin Biosynthetic Process
Tagcloud ?		appearances barely cxxc5 deg degs egfl7 exclusions exon fhl1 foxm1 gains hub inclusions ingenuity ipa maz multilateral ndrg2 pah phh plk1 rcan1 reads seq signatures suddenly synpo transcriptomic ttll1	1824c acro affiliated alopecia bossing chin clavicles contracture extremities g608g gilford groove hgps horse huazhong hutchinson joints micrognathia midline osteolysis phalanges progeria radiographical riding sclerodermatous stance stature tongji x10
Tagcloud (Difference) ?		appearances barely cxxc5 deg degs egfl7 exclusions exon fhl1 foxm1 gains hub inclusions ingenuity ipa maz multilateral ndrg2 pah phh plk1 rcan1 reads seq signatures suddenly synpo transcriptomic ttll1	1824c acro affiliated alopecia bossing chin clavicles contracture extremities g608g gilford groove hgps horse huazhong hutchinson joints micrognathia midline osteolysis phalanges progeria radiographical riding sclerodermatous stance stature tongji x10
Tagcloud (Intersection) ?