TMPO and BANF1

Number of citations of the paper that reports this interaction (PubMedID 10393804)
0

Data Source:
HPRD (two hybrid, in vitro)

		TMPO	BANF1
Description		thymopoietin	barrier to autointegration nuclear assembly factor 1
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GO Annotations	Cellular Component	Chromatin Nucleus Nuclear Envelope Nuclear Inner Membrane Chromosome Cytoplasm Membrane Nuclear Membrane	Chromatin Condensed Chromosome Nucleus Nuclear Envelope Nucleoplasm Chromosome Cytoplasm Cytosol
	Molecular Function	DNA Binding Protein Binding Lamin Binding Cadherin Binding	DNA Binding Double-stranded DNA Binding Protein Binding Identical Protein Binding Protein Homodimerization Activity
	Biological Process		DNA Repair Chromatin Organization Response To Oxidative Stress Mitotic Nuclear Membrane Reassembly Response To Virus Negative Regulation Of Protein ADP-ribosylation DNA Integration Negative Regulation Of Type I Interferon Production Positive Regulation Of Type I Interferon Production Negative Regulation Of Viral Genome Replication Negative Regulation Of Innate Immune Response Chromosome Organization CGAS/STING Signaling Pathway Negative Regulation Of CGAS/STING Signaling Pathway
Pathways		RHOA GTPase cycle RHOC GTPase cycle CDC42 GTPase cycle RAC1 GTPase cycle RAC2 GTPase cycle RHOD GTPase cycle RHOG GTPase cycle RHOJ GTPase cycle RAC3 GTPase cycle RHOF GTPase cycle	Integration of provirus 2-LTR circle formation Integration of viral DNA into host genomic DNA Autointegration results in viral DNA circles APOBEC3G mediated resistance to HIV-1 infection Vpr-mediated nuclear import of PICs Nuclear Envelope Breakdown Initiation of Nuclear Envelope (NE) Reformation
Drugs
Diseases
GWAS		Metabolite levels ( 23823483)	Acne (severe) ( 24927181) Bipolar disorder ( 31043756) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Serum uric acid levels ( 32514006)
Interacting Genes		27 interacting genes: ABL1 AKAP8L BANF1 CDK1 CEBPA CLK1 CSNK2A1 FXR1 GMCL1 GOLM1 HDAC3 KLHL6 LMNA LMNB1 LMNB2 OGT OIP5 RB1 RNF123 SGTA SGTB SRC SRPK2 STOM SUMO2 USP7 WEE2-AS1	5 interacting genes: CEBPA CRX EMD ERBIN TMPO
Entrez ID		7112	8815
HPRD ID		01777	04817
Ensembl ID		ENSG00000120802	ENSG00000175334
Uniprot IDs		G5E972 P42166 P42167 Q59G12	O75531
PDB IDs		1GJJ 1H9E 1H9F 8FN7 8FND 8FNG 8FNH 8FNJ 8FNL 8FNM 8FNN 8FNO 8FNP 8FNQ	1CI4 1QCK 2BZF 2EZX 2EZY 2EZZ 2ODG 6GHD 6RPR 6UNT 6URE 6URJ 6URK 6URL 6URN 6URR 6URZ 6US0 6US1 6US7 6USB 6USD 6USI 7ABM 7NDY 7Z21 9J8M 9J8N 9J8O
Enriched GO Terms of Interacting Partners?		Nuclear Pore Localization Nucleus Organization Negative Regulation Of Gene Expression, Epigenetic Organelle Organization Chromatin Organization Nuclear Envelope Organization Negative Regulation Of Gene Expression Heterochromatin Formation Negative Regulation Of Macromolecule Metabolic Process Epigenetic Regulation Of Gene Expression Regulation Of Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Metabolic Process Chromatin Remodeling Regulation Of Proteasomal Protein Catabolic Process PML Body Nuclear Lamina Negative Regulation Of Macromolecule Biosynthetic Process Protein Localization To Nuclear Envelope Negative Regulation Of Biosynthetic Process Nuclear Matrix Regulation Of Proteolysis Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Structural Constituent Of Nuclear Lamina TRC Complex Negative Regulation Of Proteasomal Protein Catabolic Process Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Protein-containing Complex Localization Regulation Of Gene Expression Protein Localization To Organelle Regulation Of Macromolecule Biosynthetic Process Regulation Of Metabolic Process Symbiont-mediated Disruption Of Host Cell PML Body Negative Regulation Of Proteolysis Involved In Protein Catabolic Process Regulation Of Macromolecule Metabolic Process Regulation Of Protein Metabolic Process Positive Regulation Of Metabolic Process Nuclear Migration Regulation Of Cellular Localization Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of Proteolysis Nucleus Localization Cellular Response To Fluid Shear Stress Nucleus Regulation Of Protein Catabolic Process Positive Regulation Of Catabolic Process Nuclear Envelope Rb-E2F Complex Lamin Filament Positive Regulation Of Protein Metabolic Process Negative Regulation Of Protein Metabolic Process	Nuclear Membrane Nuclear Inner Membrane CHOP-C/EBP Complex Response To Tumor Necrosis Factor Cellular Response To Tumor Necrosis Factor RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Response To Vitamin B2 White Fat Cell Proliferation C/EBP Complex RNA Polymerase II Transcription Regulator Complex System Process TMEM240-body Synaptic Receptor Adaptor Activity Negative Regulation Of Nucleotide-binding Oligomerization Domain Containing 2 Signaling Pathway ErbB-2 Class Receptor Binding Basal Protein Localization
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