ACTG1 and CAP2

Number of citations of the paper that reports this interaction (PMID 8761950)
6

Data Source:
HPRD (in vivo)

		ACTG1	CAP2
Gene Name		actin gamma 1	CAP, adenylate cyclase-associated protein, 2 (yeast)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Space Nucleus Cytosol Cytoskeleton Plasma Membrane Membrane Myofibril Filamentous Actin Extracellular Vesicular Exosome Blood Microparticle	Plasma Membrane
	Molecular Function	Structural Constituent Of Cytoskeleton Protein Binding ATP Binding Ubiquitin Protein Ligase Binding Identical Protein Binding	Actin Binding
	Biological Process	Retina Homeostasis Movement Of Cell Or Subcellular Component Axon Guidance Cell Junction Assembly Adherens Junction Organization Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Innate Immune Response Sarcomere Organization Cell-cell Junction Organization Vascular Endothelial Growth Factor Receptor Signaling Pathway Ephrin Receptor Signaling Pathway Membrane Organization Platelet Aggregation	Cytoskeleton Organization Establishment Or Maintenance Of Cell Polarity Signal Transduction Activation Of Adenylate Cyclase Activity Axon Guidance
Pathways		Axon guidance Gap junction degradation Adherens junctions interactions Translocation of GLUT4 to the plasma membrane L1CAM interactions Recycling pathway of L1 VEGFA-VEGFR2 Pathway EPHB-mediated forward signaling Interaction between L1 and Ankyrins Cell-cell junction organization EPH-ephrin mediated repulsion of cells Gap junction trafficking and regulation EPH-Ephrin signaling Fcgamma receptor (FCGR) dependent phagocytosis Regulation of actin dynamics for phagocytic cup formation Innate Immune System Cell junction organization Formation of annular gap junctions Gap junction trafficking Signaling by VEGF Cell-extracellular matrix interactions	Role of Abl in Robo-Slit signaling Axon guidance Signaling by Robo receptor
Drugs
Diseases
GWAS			Height ( 18391951)
Protein-Protein Interactions		60 interactors: ABLIM1 ACTB ANXA5 APOE ATF7IP BCAP31 BRCA1 CAP1 CAP2 CAPZA3 CCDC22 CDKN2A CFL1 CFL2 COTL1 CTBP2 CTTN CYBB DISC1 DNASE1 DSTN DYNLL1 EHHADH EIF6 FHOD1 FPR1 GIT2 GSN GZMA GZMK LGALS13 LIG4 LSP1 MAP1A MAPK6 MYO1A MYOC NDRG1 NR3C2 PFN2 PLD1 PLEC PPP1R9A PRSS23 PSEN2 PTPRO RPS6KA5 SCIN SH3GL2 ST3GAL3 SUMO4 TMSB4X TMSB4Y TNIK VASP VIL1 WASF1 WASL WDYHV1 WIPF1	7 interactors: ACTB ACTG1 CAP1 CFL2 MT1P3 PRPF40A YWHAE
Entrez ID		71	10486
HPRD ID		00017	10808
Ensembl ID		ENSG00000184009	ENSG00000112186
Uniprot IDs		P63261	B7Z1C4 B7Z214 B7Z385 E9PDI2 P40123 Q5JPJ8
PDB IDs
Enriched GO Terms of Interacting Partners?		Cytoskeleton Organization Regulation Of Actin Cytoskeleton Organization Regulation Of Cellular Component Organization Positive Regulation Of Organelle Organization Regulation Of Actin Filament-based Process Actin Cytoskeleton Organization Positive Regulation Of Cytoskeleton Organization Actin Polymerization Or Depolymerization Regulation Of Cytoskeleton Organization Actin Filament-based Process Actin Filament Organization Regulation Of Actin Polymerization Or Depolymerization Regulation Of Actin Filament Length Regulation Of Organelle Organization Organelle Organization Regulation Of Cellular Component Size Chemotaxis Cell Projection Organization Neurogenesis Negative Regulation Of Cytoskeleton Organization Regulation Of Actin Filament Depolymerization Regulation Of Protein Complex Assembly Regulation Of Actin Filament Polymerization Negative Regulation Of Actin Filament Polymerization Negative Regulation Of Protein Complex Assembly Neuron Projection Development Negative Regulation Of Protein Polymerization Movement Of Cell Or Subcellular Component Axon Guidance Generation Of Neurons Actin Filament Severing Positive Regulation Of Cellular Component Biogenesis Locomotion Regulation Of Protein Depolymerization Cell Development Response To External Stimulus Neuron Development Nervous System Development Axon Development Regulation Of Protein Complex Disassembly Regulation Of Cell Projection Organization Actin Filament Depolymerization Neuron Projection Morphogenesis Axonogenesis Neuron Differentiation Cell Projection Morphogenesis Cell Part Morphogenesis Cell Morphogenesis Involved In Neuron Differentiation Positive Regulation Of Actin Filament Polymerization Signal Transduction	Locomotion Movement Of Cell Or Subcellular Component Organelle Organization Generation Of Neurons Neurogenesis Platelet Activation Substantia Nigra Development Platelet Aggregation Nervous System Development Sarcomere Organization Cytoskeleton Organization Neural Nucleus Development Axon Guidance Retina Homeostasis Blood Coagulation Hemostasis Immune Response-regulating Signaling Pathway Myofibril Assembly Midbrain Development Adherens Junction Organization Axonogenesis Ephrin Receptor Signaling Pathway Axon Development Vascular Endothelial Growth Factor Receptor Signaling Pathway Regulation Of Body Fluid Levels Cell Morphogenesis Involved In Neuron Differentiation Actin Cytoskeleton Organization Wound Healing Chemotaxis Actomyosin Structure Organization Cell Differentiation Actin Filament-based Process Positive Regulation Of Immune Response Neuron Projection Morphogenesis Endocytosis Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cell Activation Cell Development Response To Wounding Negative Regulation Of Peptidyl-serine Dephosphorylation Regulation Of Heart Rate By Hormone Cell Morphogenesis Involved In Differentiation Striated Muscle Cell Development Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Innate Immune Response Muscle Cell Development Neuron Projection Development Cell Migration
Tagcloud ?		alteration birc7 chrcc chromophobe cpq distinctions ectopic enabled exome faah2 fusions met mitf mutated nccrccs nf2 oncocytoma oncocytomas papillary pdhb pdxdc1 pnkd prcc rcc slc5a3 transcriptome trcc unreported znf765	ac aided bpd cap1 computer correlations decided enzymatic fetal fl hc isooxytocinase klimek labor maturity measurements oxytocinase pictures prediction pregnancies relations remaining simultaneously sterility stronger takes ultrasonographic ultrasound verify
Tagcloud (Difference) ?		alteration birc7 chrcc chromophobe cpq distinctions ectopic enabled exome faah2 fusions met mitf mutated nccrccs nf2 oncocytoma oncocytomas papillary pdhb pdxdc1 pnkd prcc rcc slc5a3 transcriptome trcc unreported znf765	ac aided bpd cap1 computer correlations decided enzymatic fetal fl hc isooxytocinase klimek labor maturity measurements oxytocinase pictures prediction pregnancies relations remaining simultaneously sterility stronger takes ultrasonographic ultrasound verify
Tagcloud (Intersection) ?