ACTG1 and ABLIM1

Number of citations of the paper that reports this interaction (PMID 9245787)
24

Data Source:
HPRD (in vitro)

		ACTG1	ABLIM1
Gene Name		actin gamma 1	actin binding LIM protein 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Space Nucleus Cytosol Cytoskeleton Plasma Membrane Membrane Myofibril Filamentous Actin Extracellular Vesicular Exosome Blood Microparticle	Stress Fiber Cytoplasm Actin Cytoskeleton Lamellipodium
	Molecular Function	Structural Constituent Of Cytoskeleton Protein Binding ATP Binding Ubiquitin Protein Ligase Binding Identical Protein Binding	Actin Binding Protein Binding Zinc Ion Binding
	Biological Process	Retina Homeostasis Movement Of Cell Or Subcellular Component Axon Guidance Cell Junction Assembly Adherens Junction Organization Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Innate Immune Response Sarcomere Organization Cell-cell Junction Organization Vascular Endothelial Growth Factor Receptor Signaling Pathway Ephrin Receptor Signaling Pathway Membrane Organization Platelet Aggregation	Cytoskeleton Organization Axon Guidance Visual Perception Organ Morphogenesis Lamellipodium Assembly Cilium Assembly Positive Regulation Of Transcription From RNA Polymerase II Promoter
Pathways		Axon guidance Gap junction degradation Adherens junctions interactions Translocation of GLUT4 to the plasma membrane L1CAM interactions Recycling pathway of L1 VEGFA-VEGFR2 Pathway EPHB-mediated forward signaling Interaction between L1 and Ankyrins Cell-cell junction organization EPH-ephrin mediated repulsion of cells Gap junction trafficking and regulation EPH-Ephrin signaling Fcgamma receptor (FCGR) dependent phagocytosis Regulation of actin dynamics for phagocytic cup formation Innate Immune System Cell junction organization Formation of annular gap junctions Gap junction trafficking Signaling by VEGF Cell-extracellular matrix interactions	Axon guidance DCC mediated attractive signaling Netrin-1 signaling
Drugs
Diseases
GWAS			Obesity-related traits ( 23251661) Prostate cancer (gene x gene interaction) ( 22219177)
Protein-Protein Interactions		60 interactors: ABLIM1 ACTB ANXA5 APOE ATF7IP BCAP31 BRCA1 CAP1 CAP2 CAPZA3 CCDC22 CDKN2A CFL1 CFL2 COTL1 CTBP2 CTTN CYBB DISC1 DNASE1 DSTN DYNLL1 EHHADH EIF6 FHOD1 FPR1 GIT2 GSN GZMA GZMK LGALS13 LIG4 LSP1 MAP1A MAPK6 MYO1A MYOC NDRG1 NR3C2 PFN2 PLD1 PLEC PPP1R9A PRSS23 PSEN2 PTPRO RPS6KA5 SCIN SH3GL2 ST3GAL3 SUMO4 TMSB4X TMSB4Y TNIK VASP VIL1 WASF1 WASL WDYHV1 WIPF1	17 interactors: ACTB ACTG1 APP BEGAIN CALCOCO2 CARD9 GOLGA2 HOOK2 KCNJ12 KRT15 LDOC1 SREBF2 TRAF2 TSC22D4 USHBP1 VIM YWHAG
Entrez ID		71	3983
HPRD ID		00017	03819
Ensembl ID		ENSG00000184009	ENSG00000099204
Uniprot IDs		P63261	B3KSG3 B3KVH2 B4DQA3 B7Z4H1 O14639
PDB IDs
Enriched GO Terms of Interacting Partners?		Cytoskeleton Organization Regulation Of Actin Cytoskeleton Organization Regulation Of Cellular Component Organization Positive Regulation Of Organelle Organization Regulation Of Actin Filament-based Process Actin Cytoskeleton Organization Positive Regulation Of Cytoskeleton Organization Actin Polymerization Or Depolymerization Regulation Of Cytoskeleton Organization Actin Filament-based Process Actin Filament Organization Regulation Of Actin Polymerization Or Depolymerization Regulation Of Actin Filament Length Regulation Of Organelle Organization Organelle Organization Regulation Of Cellular Component Size Chemotaxis Cell Projection Organization Neurogenesis Negative Regulation Of Cytoskeleton Organization Regulation Of Actin Filament Depolymerization Regulation Of Protein Complex Assembly Regulation Of Actin Filament Polymerization Negative Regulation Of Actin Filament Polymerization Negative Regulation Of Protein Complex Assembly Neuron Projection Development Negative Regulation Of Protein Polymerization Movement Of Cell Or Subcellular Component Axon Guidance Generation Of Neurons Actin Filament Severing Positive Regulation Of Cellular Component Biogenesis Locomotion Regulation Of Protein Depolymerization Cell Development Response To External Stimulus Neuron Development Nervous System Development Axon Development Regulation Of Protein Complex Disassembly Regulation Of Cell Projection Organization Actin Filament Depolymerization Neuron Projection Morphogenesis Axonogenesis Neuron Differentiation Cell Projection Morphogenesis Cell Part Morphogenesis Cell Morphogenesis Involved In Neuron Differentiation Positive Regulation Of Actin Filament Polymerization Signal Transduction	Innate Immune Response Immune Response Regulation Of Protein Binding Defense Response Immune Response-regulating Signaling Pathway Platelet Activation Platelet Aggregation Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Regulation Of Binding Positive Regulation Of Immune Response Retina Homeostasis Endocytosis Response To Stress Regulation Of Lipid Transport By Negative Regulation Of Transcription From RNA Polymerase II Promoter Synaptic Growth At Neuromuscular Junction Adherens Junction Organization Immune System Process Ephrin Receptor Signaling Pathway Collateral Sprouting In Absence Of Injury Axon Guidance Vascular Endothelial Growth Factor Receptor Signaling Pathway Regulation Of Immune Response Positive Regulation Of Immune System Process Blood Coagulation Hemostasis Cholesterol Metabolic Process Generation Of Neurons Positive Regulation Of JNK Cascade Apoptotic Process Collateral Sprouting Axon Midline Choice Point Recognition Negative Regulation Of Cholesterol Efflux Sterol Metabolic Process Pattern Recognition Receptor Signaling Pathway Neurogenesis Innate Immune Response-activating Signal Transduction Positive Regulation Of Stress-activated MAPK Cascade Programmed Cell Death Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Activation Of Innate Immune Response Cell Death Death Positive Regulation Of Peptidase Activity Axon Choice Point Recognition Negative Regulation Of Glial Cell Apoptotic Process Axonogenesis Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway
Tagcloud ?		alteration birc7 chrcc chromophobe cpq distinctions ectopic enabled exome faah2 fusions met mitf mutated nccrccs nf2 oncocytoma oncocytomas papillary pdhb pdxdc1 pnkd prcc rcc slc5a3 transcriptome trcc unreported znf765
Tagcloud (Difference) ?		alteration birc7 chrcc chromophobe cpq distinctions ectopic enabled exome faah2 fusions met mitf mutated nccrccs nf2 oncocytoma oncocytomas papillary pdhb pdxdc1 pnkd prcc rcc slc5a3 transcriptome trcc unreported znf765
Tagcloud (Intersection) ?