ACTG1 and FHOD1

Number of citations of the paper that reports this interaction (PMID 12665555)
16

Data Source:
HPRD (in vivo)

		ACTG1	FHOD1
Gene Name		actin gamma 1	formin homology 2 domain containing 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Space Nucleus Cytosol Cytoskeleton Plasma Membrane Membrane Myofibril Filamentous Actin Extracellular Vesicular Exosome Blood Microparticle	Stress Fiber Nucleus Cytoplasm Membrane Bleb
	Molecular Function	Structural Constituent Of Cytoskeleton Protein Binding ATP Binding Ubiquitin Protein Ligase Binding Identical Protein Binding	Actin Binding Protein Binding Identical Protein Binding
	Biological Process	Retina Homeostasis Movement Of Cell Or Subcellular Component Axon Guidance Cell Junction Assembly Adherens Junction Organization Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Innate Immune Response Sarcomere Organization Cell-cell Junction Organization Vascular Endothelial Growth Factor Receptor Signaling Pathway Ephrin Receptor Signaling Pathway Membrane Organization Platelet Aggregation	Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Stress Fiber Assembly
Pathways		Axon guidance Gap junction degradation Adherens junctions interactions Translocation of GLUT4 to the plasma membrane L1CAM interactions Recycling pathway of L1 VEGFA-VEGFR2 Pathway EPHB-mediated forward signaling Interaction between L1 and Ankyrins Cell-cell junction organization EPH-ephrin mediated repulsion of cells Gap junction trafficking and regulation EPH-Ephrin signaling Fcgamma receptor (FCGR) dependent phagocytosis Regulation of actin dynamics for phagocytic cup formation Innate Immune System Cell junction organization Formation of annular gap junctions Gap junction trafficking Signaling by VEGF Cell-extracellular matrix interactions
Drugs
Diseases
GWAS
Protein-Protein Interactions		60 interactors: ABLIM1 ACTB ANXA5 APOE ATF7IP BCAP31 BRCA1 CAP1 CAP2 CAPZA3 CCDC22 CDKN2A CFL1 CFL2 COTL1 CTBP2 CTTN CYBB DISC1 DNASE1 DSTN DYNLL1 EHHADH EIF6 FHOD1 FPR1 GIT2 GSN GZMA GZMK LGALS13 LIG4 LSP1 MAP1A MAPK6 MYO1A MYOC NDRG1 NR3C2 PFN2 PLD1 PLEC PPP1R9A PRSS23 PSEN2 PTPRO RPS6KA5 SCIN SH3GL2 ST3GAL3 SUMO4 TMSB4X TMSB4Y TNIK VASP VIL1 WASF1 WASL WDYHV1 WIPF1	20 interactors: ACTA1 ACTG1 APC BBS1 BBS2 BBS4 BBS7 CR2 EXOSC8 GRB2 LNPEP NCOA6 PFN2 PPARG PRKG1 RAC1 RANBP2 RNF5 YWHAZ ZMYND8
Entrez ID		71	29109
HPRD ID		00017	06049
Ensembl ID		ENSG00000184009	ENSG00000135723
Uniprot IDs		P63261	Q9Y613
PDB IDs			3DAD
Enriched GO Terms of Interacting Partners?		Cytoskeleton Organization Regulation Of Actin Cytoskeleton Organization Regulation Of Cellular Component Organization Positive Regulation Of Organelle Organization Regulation Of Actin Filament-based Process Actin Cytoskeleton Organization Positive Regulation Of Cytoskeleton Organization Actin Polymerization Or Depolymerization Regulation Of Cytoskeleton Organization Actin Filament-based Process Actin Filament Organization Regulation Of Actin Polymerization Or Depolymerization Regulation Of Actin Filament Length Regulation Of Organelle Organization Organelle Organization Regulation Of Cellular Component Size Chemotaxis Cell Projection Organization Neurogenesis Negative Regulation Of Cytoskeleton Organization Regulation Of Actin Filament Depolymerization Regulation Of Protein Complex Assembly Regulation Of Actin Filament Polymerization Negative Regulation Of Actin Filament Polymerization Negative Regulation Of Protein Complex Assembly Neuron Projection Development Negative Regulation Of Protein Polymerization Movement Of Cell Or Subcellular Component Axon Guidance Generation Of Neurons Actin Filament Severing Positive Regulation Of Cellular Component Biogenesis Locomotion Regulation Of Protein Depolymerization Cell Development Response To External Stimulus Neuron Development Nervous System Development Axon Development Regulation Of Protein Complex Disassembly Regulation Of Cell Projection Organization Actin Filament Depolymerization Neuron Projection Morphogenesis Axonogenesis Neuron Differentiation Cell Projection Morphogenesis Cell Part Morphogenesis Cell Morphogenesis Involved In Neuron Differentiation Positive Regulation Of Actin Filament Polymerization Signal Transduction	Nonmotile Primary Cilium Assembly Cell Projection Organization Retina Homeostasis Cell Projection Morphogenesis Cell Part Morphogenesis Tissue Homeostasis Positive Regulation Of Organelle Organization Cellular Component Assembly Cell Morphogenesis Organelle Organization Multicellular Organismal Homeostasis Organelle Assembly Cytoskeleton Organization Cellular Response To Stimulus Negative Regulation Of Appetite By Leptin-mediated Signaling Pathway Positive Regulation Of Protein Polymerization Regulation Of Cell Projection Assembly Photoreceptor Cell Maintenance Cell Differentiation Cell Projection Assembly Fat Cell Differentiation Melanosome Transport Pigment Granule Transport Membrane Organization Establishment Of Melanosome Localization Response To Stimulus Positive Regulation Of Cellular Component Biogenesis Nervous System Development Regulation Of Organelle Organization Melanosome Localization Signal Transduction Cell Development Organ Development Homeostatic Process Regulation Of Cilium Beat Frequency Involved In Ciliary Motility Cell Surface Receptor Signaling Pathway Positive Regulation Of Protein Complex Assembly Cilium Assembly Visual Perception Sensory Perception Of Light Stimulus Anatomical Structure Formation Involved In Morphogenesis Cell Activation Signaling Cilium Organization Leptin-mediated Signaling Pathway Cell Communication Cellular Pigmentation Platelet Activation Anatomical Structure Development Blood Coagulation
Tagcloud ?		alteration birc7 chrcc chromophobe cpq distinctions ectopic enabled exome faah2 fusions met mitf mutated nccrccs nf2 oncocytoma oncocytomas papillary pdhb pdxdc1 pnkd prcc rcc slc5a3 transcriptome trcc unreported znf765	actin adhesions adhesive arrays assembly bilayers clusters coordinated depends find force formin impairs insights integrin integrins matrix maturation pillar polymerization question raises recruited rho sensing spreading steps substrates upstream
Tagcloud (Difference) ?		alteration birc7 chrcc chromophobe cpq distinctions ectopic enabled exome faah2 fusions met mitf mutated nccrccs nf2 oncocytoma oncocytomas papillary pdhb pdxdc1 pnkd prcc rcc slc5a3 transcriptome trcc unreported znf765	actin adhesions adhesive arrays assembly bilayers clusters coordinated depends find force formin impairs insights integrin integrins matrix maturation pillar polymerization question raises recruited rho sensing spreading steps substrates upstream
Tagcloud (Intersection) ?