CAP2 and ADO

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CAP2	ADO
Description		cyclase associated actin cytoskeleton regulatory protein 2	2-aminoethanethiol dioxygenase
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Postsynaptic Density Membrane	Mitochondrion Cytosol
	Molecular Function	Actin Binding Protein Binding Adenylate Cyclase Binding Identical Protein Binding	Iron Ion Binding Protein Binding Oxidoreductase Activity Oxidoreductase Activity, Acting On Single Donors With Incorporation Of Molecular Oxygen, Incorporation Of Two Atoms Of Oxygen Metal Ion Binding Cysteamine Dioxygenase Activity Dioxygenase Activity
	Biological Process	Cell Morphogenesis Cytoskeleton Organization Actin Filament Organization Establishment Or Maintenance Of Cell Polarity Signal Transduction Activation Of Adenylate Cyclase Activity CAMP-mediated Signaling Presynaptic Actin Cytoskeleton Organization	Cellular Response To Hypoxia
Pathways		Role of ABL in ROBO-SLIT signaling	Degradation of cysteine and homocysteine
Drugs
Diseases
GWAS		Haemorrhoidal disease ( 33888516) Height ( 18391951) Mitochondrial DNA levels ( 25240745) QT interval ( 29213071) Response to serotonin reuptake inhibitors in major depressive disorder ( 25897834)	Alopecia areata ( 25608926) Atopic dermatitis ( 23042114) Behcet's disease ( 33393726) Bipolar disorder ( 34002096) Breast size ( 22747683) Crohn's disease ( 28067908 22412388) Cutaneous psoriasis ( 26626624) Daytime nap ( 33568662) Diastolic blood pressure ( 27618447 27841878 27618448) Diastolic blood pressure x alcohol consumption interaction (2df test) ( 29912962) Ewing sarcoma ( 22327514) Inflammatory bowel disease ( 28067908) Lymphocyte count ( 32888494) Monocyte count ( 27863252 32888494) Platelet count ( 32888494) Selective IgA deficiency ( 27723758) Systemic lupus erythematosus ( 28714469) Systolic blood pressure ( 27841878 27618447) Ulcerative colitis ( 28067908) Urinary albumin excretion ( 30220432) Urinary albumin excretion (no hypertensive medication) ( 30220432) Urinary albumin-to-creatinine ratio ( 31630189) Venlafaxine response in generalised anxiety disorder (remitters vs non-remitters after 12 weeks) ( 28437668) Vogt-Koyanagi-Harada syndrome ( 25108386)
Interacting Genes		11 interacting genes: ACTG1 ADO ALAS1 CAP1 CFL2 DNM1L DSCAM GRXCR1 MT1P3 PRPF40A YWHAE	2 interacting genes: CAP2 DISC1
Entrez ID		10486	84890
HPRD ID		10808	12566
Ensembl ID		ENSG00000112186	ENSG00000181915
Uniprot IDs		B7Z385 E9PDI2 P40123	B3KXN9 Q96SZ5
PDB IDs			7REI 8U9J 8UAN
Enriched GO Terms of Interacting Partners?			Postsynaptic Density Presynaptic Cytoskeleton Organization CAMP-mediated Signaling Presynaptic Actin Cytoskeleton Organization Radial Glia-guided Pyramidal Neuron Migration Pyramidal Neuron Migration To Cerebral Cortex Cerebral Cortex Radial Glia-guided Migration Central Region Of Growth Cone Positive Regulation Of Lyase Activity Adenylate Cyclase Binding Activation Of Adenylate Cyclase Activity Positive Regulation Of Adenylate Cyclase Activity Positive Regulation Of Cyclase Activity Cytoskeleton Organization Positive Regulation Of Neuroblast Proliferation Detection Of Temperature Stimulus Detection Of Temperature Stimulus Involved In Sensory Perception Of Pain Mitochondrial Calcium Ion Homeostasis Cell Proliferation In Forebrain Detection Of Temperature Stimulus Involved In Sensory Perception Glial Cell Migration Cerebral Cortex Radially Oriented Cell Migration Protein Localization To Centrosome Regulation Of Synapse Maturation Cerebral Cortex Cell Migration Dynein Complex Regulation Of Neuroblast Proliferation Telencephalon Cell Migration Response To Electrical Stimulus Kinesin Binding Forebrain Cell Migration Kinesin Complex Positive Regulation Of Axon Extension Ciliary Base Protein Localization To Cytoskeleton Intermediate Filament Cytoskeleton Non-motile Cilium Assembly Regulation Of Dendritic Spine Development Positive Regulation Of Neural Precursor Cell Proliferation Positive Regulation Of Cell-matrix Adhesion Neuron Cellular Homeostasis Regulation Of Synaptic Transmission, Glutamatergic Positive Regulation Of Axonogenesis Cell Body Regulation Of Axon Extension TOR Signaling Identical Protein Binding Intracellular Signal Transduction Microtubule Organizing Center Regulation Of Neural Precursor Cell Proliferation
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