TFAM and AGTRAP

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		TFAM	AGTRAP
Gene Name		transcription factor A, mitochondrial	angiotensin II receptor-associated protein
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Mitochondrion Mitochondrial Matrix Cytosol Mitochondrial Nucleoid	Golgi Membrane Nucleoplasm Cytoplasm Endoplasmic Reticulum Membrane Plasma Membrane Cell Cortex Integral Component Of Membrane Cytoplasmic Vesicle Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription Chromatin Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding DNA Binding, Bending Heat Shock Protein Binding Poly(A) RNA Binding Mitochondrial Light Strand Promoter Sense Binding	Angiotensin Type II Receptor Activity Protein Binding
	Biological Process	DNA-dependent DNA Replication Chromatin Remodeling Regulation Of Transcription From RNA Polymerase I Promoter Transcription From Mitochondrial Promoter Transcription Initiation From Mitochondrial Promoter Organelle Organization Mitochondrion Organization Gene Expression Mitochondrial Respiratory Chain Complex Assembly Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter	Response To Hypoxia Regulation Of Blood Pressure Angiotensin-activated Signaling Pathway
Pathways		Organelle biogenesis and maintenance Mitochondrial transcription initiation RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription Transcription from mitochondrial promoters Transcriptional activation of mitochondrial biogenesis Mitochondrial biogenesis
Drugs
Diseases
GWAS		Height ( 23456168)	Systolic blood pressure ( 19430483)
Protein-Protein Interactions		5 interactors: AGTRAP ARL6IP1 PNP TFB1M TFB2M	70 interactors: ACSF2 ADCK3 AGTR1 AGTR2 ALDH18A1 AP3M1 ARAF ARFIP2 BPIFA2 C12orf10 CAPNS1 CD160 CPLX1 CRCT1 DDA1 DDX55 DGCR6 FAM114A1 FAM160A2 FAM64A FARS2 FASTKD3 FATE1 GABARAPL2 GAD1 GAD2 GDNF GNB2L1 GTF3C1 HARS2 HIST1H4G HMGB1 HSCB HSPA4 ISCU KIAA0368 LMO2 LNX1 MCEE MIEF1 MIEF2 MRM1 MTERF3 MUTYH NDRG4 NFU1 NFYB NKG7 PBX3 PCTP PDHX PITPNC1 PTPN9 RMDN2 SENP2 SNX1 SPG21 SSX3 SSX5 STAG3L1 SUCLA2 SYT16 TBRG4 TCEANC2 TFAM TPD52L3 TUBA1B TXN2 ZFYVE21 ZNF391
Entrez ID		7019	57085
HPRD ID		02702	16379
Ensembl ID		ENSG00000108064	ENSG00000177674
Uniprot IDs		E5KSU5 Q00059	Q6RW13
PDB IDs		3FGH 3TMM 3TQ6
Enriched GO Terms of Interacting Partners?		RRNA Methylation RRNA Modification RNA Methylation NAD Biosynthesis Via Nicotinamide Riboside Salvage Pathway Inosine Catabolic Process Nicotinamide Riboside Catabolic Process RRNA Processing RRNA Metabolic Process Interleukin-2 Secretion Urate Biosynthetic Process RNA Modification Transcription Initiation From Mitochondrial Promoter Ribosome Biogenesis Angiotensin-activated Signaling Pathway Ribonucleoprotein Complex Biogenesis Interleukin-2 Production Transcription From Mitochondrial Promoter Urate Metabolic Process Purine Ribonucleoside Catabolic Process Mitochondrion Organization Methylation NcRNA Metabolic Process Regulation Of Appetite Purine-containing Compound Salvage NAD Biosynthetic Process Cytokine Secretion Purine Nucleotide Catabolic Process Purine Nucleobase Metabolic Process Positive Regulation Of Alpha-beta T Cell Differentiation NAD Metabolic Process	Succinate Metabolic Process Glutamate Decarboxylation To Succinate Glutamate Metabolic Process Iron-sulfur Cluster Assembly Renin-angiotensin Regulation Of Aldosterone Production Regulation Of Blood Vessel Size By Renin-angiotensin Dicarboxylic Acid Metabolic Process Glutamate Catabolic Process Angiotensin-activated Signaling Pathway Positive Regulation Of Oxidoreductase Activity Positive Regulation Of Protein Homooligomerization Positive Regulation Of Mitochondrial Fission Small Molecule Metabolic Process Negative Regulation Of Phagocytosis Regulation Of Mitochondrial Fission Regulation Of Blood Volume By Renin-angiotensin Dicarboxylic Acid Catabolic Process Neurotransmitter Biosynthetic Process Carboxylic Acid Metabolic Process Regulation Of Oxidoreductase Activity Positive Regulation Of Branching Involved In Ureteric Bud Morphogenesis Positive Regulation Of Protein Oligomerization Regulation Of Renal Sodium Excretion Regulation Of Branching Involved In Ureteric Bud Morphogenesis Carboxylic Acid Catabolic Process Regulation Of Systemic Arterial Blood Pressure By Renin-angiotensin Organic Acid Metabolic Process Positive Regulation Of Monooxygenase Activity Regulation Of Excretion Exploration Behavior Regulation Of Protein Oligomerization Neurotransmitter Metabolic Process Neurotransmitter Secretion Mitochondrion Organization Ornithine Biosynthetic Process Negative Regulation Of Apoptotic Cell Clearance Succinyl-CoA Pathway Posterior Compartment Specification Anterior Compartment Pattern Formation Aldosterone Secretion Nitrogen Fixation Vasodilation By Angiotensin Involved In Regulation Of Systemic Arterial Blood Pressure L-methylmalonyl-CoA Metabolic Process Phospholipase C-activating Angiotensin-activated Signaling Pathway Positive Regulation Of Embryonic Development Positive Regulation Of Protein Targeting To Membrane Metanephros Morphogenesis Cellular Amino Acid Catabolic Process Cardiac Muscle Tissue Growth Biosynthetic Process
Tagcloud ?		analogs apoptogenic biogenesis coded counterpart diminished dissipation doses her2high inducer innovation lowered mitocans mitochondrial mitochondrially mitoves mtdna replicated respiration succinate suppress suppresses targeted tocopheryl transcript transcripts unlike untargeted vitamin	adrenal alpha1 apelin apln covers ephx2 epoxide genesis gja1 glands hydrolase hypertensive isolating kynu kynureninase kyoto normotensive osteonectin prone rgs2 rising shr shrsp sparc spock2 substrains urotensin uts2 wky
Tagcloud (Difference) ?		analogs apoptogenic biogenesis coded counterpart diminished dissipation doses her2high inducer innovation lowered mitocans mitochondrial mitochondrially mitoves mtdna replicated respiration succinate suppress suppresses targeted tocopheryl transcript transcripts unlike untargeted vitamin	adrenal alpha1 apelin apln covers ephx2 epoxide genesis gja1 glands hydrolase hypertensive isolating kynu kynureninase kyoto normotensive osteonectin prone rgs2 rising shr shrsp sparc spock2 substrains urotensin uts2 wky
Tagcloud (Intersection) ?