TFAM and AGTRAP

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid, two hybrid)

		TFAM	AGTRAP
Description		transcription factor A, mitochondrial	angiotensin II receptor associated protein
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Mitochondrion Mitochondrial Matrix Cytosol Protein-containing Complex Mitochondrial Nucleoid	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Plasma Membrane Cell Cortex Membrane Cytoplasmic Vesicle Membrane Cytoplasmic Vesicle
	Molecular Function	Mitochondrial Promoter Sequence-specific DNA Binding Transcription Coactivator Binding DNA Binding Chromatin Binding RNA Binding Protein Binding Heat Shock Protein Binding Mitochondrial Transcription Factor Activity Sequence-specific DNA Binding	Angiotensin Type II Receptor Activity Protein Binding Identical Protein Binding
	Biological Process	Response To Hypoxia Mitochondrial Transcription Transcription Initiation At Mitochondrial Promoter Response To Nutrient Mitochondrial Respiratory Chain Complex Assembly	Response To Hypoxia Regulation Of Blood Pressure Angiotensin-activated Signaling Pathway
Pathways		Mitochondrial transcription initiation Transcriptional activation of mitochondrial biogenesis Transcriptional activation of mitochondrial biogenesis Mitochondrial protein degradation	Signaling by BRAF and RAF1 fusions
Drugs
Diseases
GWAS		Blood urea nitrogen levels ( 29403010) Height ( 23456168) Metabolite levels ( 23823483) Midgestational circulating levels of PCBs ( 28235828) Mitochondrial heteroplasmy measurement ( 33731350) Refractive error ( 32231278)	Arterial stiffness (brachial-femoral pulse wave velocity) ( 32790701) Basophil percentage of white cells ( 32888494) Systolic blood pressure ( 19430483)
Interacting Genes		10 interacting genes: AGTRAP ARL6IP1 COL8A2 MGST3 PNP STATH TECR TFB1M TFB2M TSPAN1	138 interacting genes: ACSF2 AGTR1 AGTR2 ALDH18A1 ANKS6 AP3M1 APOA4 AQP6 ARAF ARFIP2 ARHGAP1 ATP5F1E BCL2L13 BPIFA2 CAPNS1 CCDC70 CD160 CD79A CELA3A CIAO2A COQ8A CPLX1 CPLX4 CRCT1 CYB5R3 CYBC1 DDA1 DDX55 DGCR6 DIABLO DNAJC1 ECPAS ERGIC3 ETFRF1 FAM114A1 FAM209A FARS2 FASTKD3 FATE1 FFAR2 FGA FHIP1B FNDC9 GABARAPL2 GAD1 GAD2 GDNF GPR152 GPX8 GTF2H1 GTF3C1 H4C7 HARS2 HIBADH HMGB1 HSBP1L1 HSCB HSD17B13 HSFX1 HSFX2 HSPA4 IL7R ISCU KCNK5 KIR2DL3 KIR3DL3 LMNA LMO2 LNX1 LRRC4C LRRC59 MCEE MGST3 MIEF1 MIEF2 MMD MRM1 MRPL11 MRRF MTERF3 MUTYH MYG1 NDRG4 NDUFAF3 NFU1 NFYB NKG7 PBX3 PCTP PCYT1A PDHX PIMREG PITPNC1 PNPO POLDIP2 PPIF PRPF18 PTPN9 RAB30 RACK1 RBFA RETREG3 RMDN2 S100B SCAND1 SENP2 SH3GLB1 SLC18A1 SLC7A14 SMG9 SNX1 SPG21 SSX3 SSX5 STAG3L1 STAR STARD4 STMN4 STX1A SUCLA2 SYT16 TBRG4 TCEA2 TCEANC2 TFAM THAP4 TMEM139 TMEM14B TMEM31 TMPPE TPD52L3 TTPA TUBA1B TXN2 UBE2I YARS2 ZFYVE21 ZNF391
Entrez ID		7019	57085
HPRD ID		02702	16379
Ensembl ID		ENSG00000108064	ENSG00000177674
Uniprot IDs		E5KSU5 Q00059	Q6RW13
PDB IDs		3FGH 3TMM 3TQ6 4NNU 4NOD 6ERP 6ERQ 6HB4 6HC3 7LBW 7LBX
Enriched GO Terms of Interacting Partners?		RRNA (adenine-N6,N6-)-dimethyltransferase Activity Mitochondrial Transcription Factor Activity Transcription Initiation At Mitochondrial Promoter RRNA Methylation RRNA Modification Mitochondrial RNA Metabolic Process Mitochondrial Nucleoid Collagen Type VIII Trimer Purine-nucleoside Phosphorylase Activity Purine Nucleobase Binding Urate Biosynthetic Process Nicotinamide Riboside Catabolic Process Nucleobase-containing Compound Biosynthetic Process Guanosine Phosphorylase Activity Inosine Catabolic Process Deoxyinosine Catabolic Process Extracellular Matrix Constituent, Lubricant Activity Very-long-chain Enoyl-CoA Reductase Activity DNA-templated Transcription Initiation RNA Methylation Small Molecule Biosynthetic Process Endoplasmic Reticulum Membrane Nucleoside Binding DAMP Catabolic Process Deoxyadenosine Catabolic Process Structural Constituent Of Tooth Enamel Hydroxyapatite Binding Very-long-chain Fatty Acyl-CoA Dehydrogenase Activity Positive Regulation Of L-glutamate Import Across Plasma Membrane Macromolecule Methylation Angiotensin Type II Receptor Activity RRNA (adenine-N6-)-methyltransferase Activity Leukotriene-C4 Synthase Activity Purine Ribonucleoside Catabolic Process Purine Deoxyribonucleoside Metabolic Process IMP Catabolic Process Regulation Of Endoplasmic Reticulum Tubular Network Organization Deoxyribonucleoside Catabolic Process Pentosyltransferase Activity Saliva Secretion Sec61 Translocon Complex Endoplasmic Reticulum Tubular Network Formation RNA Modification Purine Ribonucleoside Salvage Purine Nucleoside Catabolic Process Methyltransferase Activity Allantoin Metabolic Process Endoplasmic Reticulum Tubular Network Membrane Organization Mitochondrial Transcription Urate Metabolic Process	Mitochondrial Matrix Mitochondrion Protein Binding Lipid Binding Succinate Metabolic Process Gamma-aminobutyrate Shunt Glutamate Decarboxylase Activity
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