TFAM and TFB1M

Number of citations of the paper that reports this interaction (PMID 12068295)
109

Data Source:
HPRD (in vitro, in vivo)

		TFAM	TFB1M
Gene Name		transcription factor A, mitochondrial	transcription factor B1, mitochondrial
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Mitochondrion Mitochondrial Matrix Cytosol Mitochondrial Nucleoid	Mitochondrial Matrix Mitochondrial Nucleoid
	Molecular Function	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription Chromatin Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding DNA Binding, Bending Heat Shock Protein Binding Poly(A) RNA Binding Mitochondrial Light Strand Promoter Sense Binding	RRNA (adenine-N6,N6-)-dimethyltransferase Activity DNA Binding Protein Binding Poly(A) RNA Binding
	Biological Process	DNA-dependent DNA Replication Chromatin Remodeling Regulation Of Transcription From RNA Polymerase I Promoter Transcription From Mitochondrial Promoter Transcription Initiation From Mitochondrial Promoter Organelle Organization Mitochondrion Organization Gene Expression Mitochondrial Respiratory Chain Complex Assembly Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Organelle Organization Mitochondrion Organization RRNA Methylation
Pathways		Organelle biogenesis and maintenance Mitochondrial transcription initiation RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription Transcription from mitochondrial promoters Transcriptional activation of mitochondrial biogenesis Mitochondrial biogenesis	Organelle biogenesis and maintenance Transcriptional activation of mitochondrial biogenesis Mitochondrial biogenesis
Drugs
Diseases
GWAS		Height ( 23456168)
Protein-Protein Interactions		5 interactors: AGTRAP ARL6IP1 PNP TFB1M TFB2M	2 interactors: POLRMT TFAM
Entrez ID		7019	51106
HPRD ID		02702	09515
Ensembl ID		ENSG00000108064
Uniprot IDs		E5KSU5 Q00059	E5KTM5 Q8WVM0
PDB IDs		3FGH 3TMM 3TQ6
Enriched GO Terms of Interacting Partners?		RRNA Methylation RRNA Modification RNA Methylation NAD Biosynthesis Via Nicotinamide Riboside Salvage Pathway Inosine Catabolic Process Nicotinamide Riboside Catabolic Process RRNA Processing RRNA Metabolic Process Interleukin-2 Secretion Urate Biosynthetic Process RNA Modification Transcription Initiation From Mitochondrial Promoter Ribosome Biogenesis Angiotensin-activated Signaling Pathway Ribonucleoprotein Complex Biogenesis Interleukin-2 Production Transcription From Mitochondrial Promoter Urate Metabolic Process Purine Ribonucleoside Catabolic Process Mitochondrion Organization Methylation NcRNA Metabolic Process Regulation Of Appetite Purine-containing Compound Salvage NAD Biosynthetic Process Cytokine Secretion Purine Nucleotide Catabolic Process Purine Nucleobase Metabolic Process Positive Regulation Of Alpha-beta T Cell Differentiation NAD Metabolic Process	Transcription Initiation From Mitochondrial Promoter Transcription From Mitochondrial Promoter DNA-templated Transcription, Initiation Mitochondrion Organization Regulation Of Transcription From RNA Polymerase I Promoter Mitochondrial Respiratory Chain Complex Assembly
Tagcloud ?		analogs apoptogenic biogenesis coded counterpart diminished dissipation doses her2high inducer innovation lowered mitocans mitochondrial mitochondrially mitoves mtdna replicated respiration succinate suppress suppresses targeted tocopheryl transcript transcripts unlike untargeted vitamin	adam19 atria conduction connexins coq7 cx40 dyrk1a electrocardiogram f5 gabpa hmgn1 lethality monosomic morc3 ms5yah natal ncx1 pde10a pinpoint precordial scn10a scn1b scn5a slc5a3 slc8a1 tiam1 trisomic ts65dn ventricles
Tagcloud (Difference) ?		analogs apoptogenic biogenesis coded counterpart diminished dissipation doses her2high inducer innovation lowered mitocans mitochondrial mitochondrially mitoves mtdna replicated respiration succinate suppress suppresses targeted tocopheryl transcript transcripts unlike untargeted vitamin	adam19 atria conduction connexins coq7 cx40 dyrk1a electrocardiogram f5 gabpa hmgn1 lethality monosomic morc3 ms5yah natal ncx1 pde10a pinpoint precordial scn10a scn1b scn5a slc5a3 slc8a1 tiam1 trisomic ts65dn ventricles
Tagcloud (Intersection) ?