TFAM and TFB1M

Number of citations of the paper that reports this interaction (PubMedID 12897151)
33

Data Source:
HPRD (in vitro, in vivo)

		TFAM	TFB1M
Description		transcription factor A, mitochondrial	transcription factor B1, mitochondrial
Image
GO Annotations	Cellular Component	Nucleus Mitochondrion Mitochondrial Matrix Cytosol Protein-containing Complex Mitochondrial Nucleoid	Mitochondrion Mitochondrial Matrix Mitochondrial Nucleoid
	Molecular Function	Mitochondrial Promoter Sequence-specific DNA Binding Transcription Coactivator Binding DNA Binding Chromatin Binding RNA Binding Protein Binding Heat Shock Protein Binding Mitochondrial Transcription Factor Activity Sequence-specific DNA Binding	RRNA (adenine-N6,N6-)-dimethyltransferase Activity DNA Binding RNA Binding Protein Binding Methyltransferase Activity Transferase Activity Mitochondrial Transcription Factor Activity S-adenosyl-L-methionine Binding
	Biological Process	Response To Hypoxia Mitochondrial Transcription Transcription Initiation At Mitochondrial Promoter Response To Nutrient Mitochondrial Respiratory Chain Complex Assembly	RRNA Modification RRNA Processing Transcription Initiation At Mitochondrial Promoter RRNA Methylation Methylation
Pathways		Mitochondrial transcription initiation Transcriptional activation of mitochondrial biogenesis Transcriptional activation of mitochondrial biogenesis Mitochondrial protein degradation	Transcriptional activation of mitochondrial biogenesis rRNA modification in the mitochondrion
Drugs
Diseases
GWAS		Blood urea nitrogen levels ( 29403010) Height ( 23456168) Metabolite levels ( 23823483) Midgestational circulating levels of PCBs ( 28235828) Mitochondrial heteroplasmy measurement ( 33731350) Refractive error ( 32231278)	Dimensional psychopathology (Arousal) ( 29496196) Dimensional psychopathology (Negative) ( 29496196) Gut microbiota (bacterial taxa, rank normal transformation method) ( 32572223) Metabolite levels ( 23823483) Waist-hip ratio ( 28552196) Waist-to-hip ratio adjusted for BMI ( 28552196)
Interacting Genes		10 interacting genes: AGTRAP ARL6IP1 COL8A2 MGST3 PNP STATH TECR TFB1M TFB2M TSPAN1	2 interacting genes: POLRMT TFAM
Entrez ID		7019	51106
HPRD ID		02702	09515
Ensembl ID		ENSG00000108064	ENSG00000029639
Uniprot IDs		E5KSU5 Q00059	E5KTM5 Q8WVM0
PDB IDs		3FGH 3TMM 3TQ6 4NNU 4NOD 6ERP 6ERQ 6HB4 6HC3 7LBW 7LBX	6AAX 6AJK 8CSP 8CSQ 8CSR 8CSU
Enriched GO Terms of Interacting Partners?		RRNA (adenine-N6,N6-)-dimethyltransferase Activity Mitochondrial Transcription Factor Activity Transcription Initiation At Mitochondrial Promoter RRNA Methylation RRNA Modification Mitochondrial RNA Metabolic Process Mitochondrial Nucleoid Collagen Type VIII Trimer Purine-nucleoside Phosphorylase Activity Purine Nucleobase Binding Urate Biosynthetic Process Nicotinamide Riboside Catabolic Process Nucleobase-containing Compound Biosynthetic Process Guanosine Phosphorylase Activity Inosine Catabolic Process Deoxyinosine Catabolic Process Extracellular Matrix Constituent, Lubricant Activity Very-long-chain Enoyl-CoA Reductase Activity DNA-templated Transcription Initiation RNA Methylation Small Molecule Biosynthetic Process Endoplasmic Reticulum Membrane Nucleoside Binding DAMP Catabolic Process Deoxyadenosine Catabolic Process Structural Constituent Of Tooth Enamel Hydroxyapatite Binding Very-long-chain Fatty Acyl-CoA Dehydrogenase Activity Positive Regulation Of L-glutamate Import Across Plasma Membrane Macromolecule Methylation Angiotensin Type II Receptor Activity RRNA (adenine-N6-)-methyltransferase Activity Leukotriene-C4 Synthase Activity Purine Ribonucleoside Catabolic Process Purine Deoxyribonucleoside Metabolic Process IMP Catabolic Process Regulation Of Endoplasmic Reticulum Tubular Network Organization Deoxyribonucleoside Catabolic Process Pentosyltransferase Activity Saliva Secretion Sec61 Translocon Complex Endoplasmic Reticulum Tubular Network Formation RNA Modification Purine Ribonucleoside Salvage Purine Nucleoside Catabolic Process Methyltransferase Activity Allantoin Metabolic Process Endoplasmic Reticulum Tubular Network Membrane Organization Mitochondrial Transcription Urate Metabolic Process	Mitochondrial Promoter Sequence-specific DNA Binding Transcription Initiation At Mitochondrial Promoter Mitochondrial Transcription Mitochondrial Nucleoid Mitochondrial RNA Metabolic Process DNA-templated Transcription Initiation Mitochondrial DNA-directed RNA Polymerase Complex Macromolecule Biosynthetic Process Mitochondrial Transcription Factor Activity Vascular Endothelial Growth Factor Receptor 1 Binding Vascular Endothelial Growth Factor Receptor Binding Response To Decreased Oxygen Levels Response To Hypoxia Positive Regulation Of Vascular Wound Healing Positive Regulation Of Mast Cell Chemotaxis Response To Oxygen Levels 5'-3' RNA Polymerase Activity Regulation Of Mast Cell Chemotaxis Mitochondrial Matrix DNA-templated Transcription Mitochondrial DNA Replication Sequence-specific DNA Binding Positive Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Regulation Of Vascular Wound Healing Induction Of Positive Chemotaxis Positive Regulation Of Vascular Permeability Mitochondrial DNA Metabolic Process Vascular Endothelial Growth Factor Signaling Pathway Positive Regulation Of Positive Chemotaxis Coronary Vasculature Development DNA-directed RNA Polymerase Activity 3'-5'-RNA Exonuclease Activity Protein-containing Complex Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Chemoattractant Activity DNA-directed RNA Polymerase Complex Sprouting Angiogenesis Vascular Endothelial Growth Factor Receptor Signaling Pathway Nucleobase-containing Compound Biosynthetic Process Cardiac Muscle Contraction Positive Chemotaxis Regulation Of Vascular Permeability DNA-templated DNA Replication Transcription Coactivator Binding Positive Regulation Of Peptidyl-tyrosine Phosphorylation Heat Shock Protein Binding Positive Regulation Of Wound Healing Platelet Alpha Granule Lumen
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?