TFAM and TFB2M

Number of citations of the paper that reports this interaction (PMID 12068295)
109

Data Source:
HPRD (in vitro)

		TFAM	TFB2M
Gene Name		transcription factor A, mitochondrial	transcription factor B2, mitochondrial
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Mitochondrion Mitochondrial Matrix Cytosol Mitochondrial Nucleoid	Mitochondrial Matrix Mitochondrial Nucleoid
	Molecular Function	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription Chromatin Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding DNA Binding, Bending Heat Shock Protein Binding Poly(A) RNA Binding Mitochondrial Light Strand Promoter Sense Binding	RRNA (adenine-N6,N6-)-dimethyltransferase Activity Transcription Cofactor Activity Poly(A) RNA Binding
	Biological Process	DNA-dependent DNA Replication Chromatin Remodeling Regulation Of Transcription From RNA Polymerase I Promoter Transcription From Mitochondrial Promoter Transcription Initiation From Mitochondrial Promoter Organelle Organization Mitochondrion Organization Gene Expression Mitochondrial Respiratory Chain Complex Assembly Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter	Transcription From Mitochondrial Promoter Transcription Initiation From Mitochondrial Promoter Organelle Organization Mitochondrion Organization Gene Expression RRNA Methylation Positive Regulation Of Transcription, DNA-templated
Pathways		Organelle biogenesis and maintenance Mitochondrial transcription initiation RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription Transcription from mitochondrial promoters Transcriptional activation of mitochondrial biogenesis Mitochondrial biogenesis	Organelle biogenesis and maintenance Mitochondrial transcription initiation RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription Transcription from mitochondrial promoters Transcriptional activation of mitochondrial biogenesis Mitochondrial biogenesis
Drugs
Diseases
GWAS		Height ( 23456168)
Protein-Protein Interactions		5 interactors: AGTRAP ARL6IP1 PNP TFB1M TFB2M	3 interactors: PNP POLRMT TFAM
Entrez ID		7019	64216
HPRD ID		02702	09520
Ensembl ID		ENSG00000108064	ENSG00000162851
Uniprot IDs		E5KSU5 Q00059	Q9H5Q4
PDB IDs		3FGH 3TMM 3TQ6
Enriched GO Terms of Interacting Partners?		RRNA Methylation RRNA Modification RNA Methylation NAD Biosynthesis Via Nicotinamide Riboside Salvage Pathway Inosine Catabolic Process Nicotinamide Riboside Catabolic Process RRNA Processing RRNA Metabolic Process Interleukin-2 Secretion Urate Biosynthetic Process RNA Modification Transcription Initiation From Mitochondrial Promoter Ribosome Biogenesis Angiotensin-activated Signaling Pathway Ribonucleoprotein Complex Biogenesis Interleukin-2 Production Transcription From Mitochondrial Promoter Urate Metabolic Process Purine Ribonucleoside Catabolic Process Mitochondrion Organization Methylation NcRNA Metabolic Process Regulation Of Appetite Purine-containing Compound Salvage NAD Biosynthetic Process Cytokine Secretion Purine Nucleotide Catabolic Process Purine Nucleobase Metabolic Process Positive Regulation Of Alpha-beta T Cell Differentiation NAD Metabolic Process	Transcription Initiation From Mitochondrial Promoter Transcription From Mitochondrial Promoter NAD Biosynthesis Via Nicotinamide Riboside Salvage Pathway Inosine Catabolic Process Nicotinamide Riboside Catabolic Process Interleukin-2 Secretion Urate Biosynthetic Process DNA-templated Transcription, Initiation Mitochondrion Organization Interleukin-2 Production Urate Metabolic Process Purine Ribonucleoside Catabolic Process Regulation Of Transcription From RNA Polymerase I Promoter Regulation Of Appetite Purine-containing Compound Salvage Mitochondrial Respiratory Chain Complex Assembly NAD Biosynthetic Process Cytokine Secretion Purine Nucleotide Catabolic Process Purine Nucleobase Metabolic Process Positive Regulation Of Alpha-beta T Cell Differentiation NAD Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Nucleotide Catabolic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of T Cell Proliferation Positive Regulation Of T Cell Differentiation Nicotinamide Nucleotide Metabolic Process Neuropeptide Signaling Pathway Positive Regulation Of Lymphocyte Differentiation Feeding Behavior Nitrogen Compound Metabolic Process DNA-dependent DNA Replication Positive Regulation Of Lymphocyte Proliferation Positive Regulation Of Mononuclear Cell Proliferation Digestion Protein Secretion Regulation Of T Cell Differentiation Cytokine Production Regulation Of T Cell Proliferation Organophosphate Catabolic Process Coenzyme Biosynthetic Process
Tagcloud ?		analogs apoptogenic biogenesis coded counterpart diminished dissipation doses her2high inducer innovation lowered mitocans mitochondrial mitochondrially mitoves mtdna replicated respiration succinate suppress suppresses targeted tocopheryl transcript transcripts unlike untargeted vitamin
Tagcloud (Difference) ?		analogs apoptogenic biogenesis coded counterpart diminished dissipation doses her2high inducer innovation lowered mitocans mitochondrial mitochondrially mitoves mtdna replicated respiration succinate suppress suppresses targeted tocopheryl transcript transcripts unlike untargeted vitamin
Tagcloud (Intersection) ?