TFAM

Name	transcription factor A, mitochondrial
Structure
Interactors	10 interactors: AGTRAP ARL6IP1 COL8A2 MGST3 PNP STATH TECR TFB1M TFB2M TSPAN1
GO Annotations	Cellular Component	Nucleus Mitochondrion Mitochondrial Matrix Cytosol Protein-containing Complex Mitochondrial Nucleoid
	Molecular Function	Mitochondrial Promoter Sequence-specific DNA Binding Transcription Coactivator Binding DNA Binding Chromatin Binding RNA Binding Protein Binding Heat Shock Protein Binding Mitochondrial Transcription Factor Activity Sequence-specific DNA Binding
	Biological Process	Response To Hypoxia Mitochondrial Transcription Transcription Initiation At Mitochondrial Promoter Response To Nutrient Mitochondrial Respiratory Chain Complex Assembly
Pathways	Mitochondrial transcription initiation Transcriptional activation of mitochondrial biogenesis Transcriptional activation of mitochondrial biogenesis Mitochondrial protein degradation
GWAS	Blood urea nitrogen levels ( 29403010 ) Height ( 23456168 ) Metabolite levels ( 23823483 ) Midgestational circulating levels of PCBs ( 28235828 ) Mitochondrial heteroplasmy measurement ( 33731350 ) Refractive error ( 32231278 )
Entrez ID	7019
HPRD ID	02702
Ensembl ID	ENSG00000108064
Uniprot IDs	E5KSU5 Q00059
PDB IDs	3FGH 3TMM 3TQ6 4NNU 4NOD 6ERP 6ERQ 6HB4 6HC3 7LBW 7LBX
GO Terms Enriched among Interactors ?	RRNA (adenine-N6,N6-)-dimethyltransferase Activity Mitochondrial Transcription Factor Activity Transcription Initiation At Mitochondrial Promoter RRNA Methylation RRNA Modification Mitochondrial RNA Metabolic Process Mitochondrial Nucleoid Collagen Type VIII Trimer Purine-nucleoside Phosphorylase Activity Purine Nucleobase Binding Urate Biosynthetic Process Nicotinamide Riboside Catabolic Process Nucleobase-containing Compound Biosynthetic Process Guanosine Phosphorylase Activity Inosine Catabolic Process Deoxyinosine Catabolic Process Extracellular Matrix Constituent, Lubricant Activity Very-long-chain Enoyl-CoA Reductase Activity DNA-templated Transcription Initiation RNA Methylation Small Molecule Biosynthetic Process Endoplasmic Reticulum Membrane Nucleoside Binding DAMP Catabolic Process Deoxyadenosine Catabolic Process Structural Constituent Of Tooth Enamel Hydroxyapatite Binding Very-long-chain Fatty Acyl-CoA Dehydrogenase Activity Positive Regulation Of L-glutamate Import Across Plasma Membrane Macromolecule Methylation Angiotensin Type II Receptor Activity RRNA (adenine-N6-)-methyltransferase Activity Leukotriene-C4 Synthase Activity Purine Ribonucleoside Catabolic Process Purine Deoxyribonucleoside Metabolic Process IMP Catabolic Process Regulation Of Endoplasmic Reticulum Tubular Network Organization Deoxyribonucleoside Catabolic Process Pentosyltransferase Activity Saliva Secretion Sec61 Translocon Complex Endoplasmic Reticulum Tubular Network Formation RNA Modification Purine Ribonucleoside Salvage Purine Nucleoside Catabolic Process Methyltransferase Activity Allantoin Metabolic Process Endoplasmic Reticulum Tubular Network Membrane Organization Mitochondrial Transcription Urate Metabolic Process