TFAM

Gene Name		transcription factor A, mitochondrial
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Gene Ontology Annotations	Cellular Component	Nucleus Mitochondrion Mitochondrial Matrix Cytosol Mitochondrial Nucleoid
	Molecular Function	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription Chromatin Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding DNA Binding, Bending Heat Shock Protein Binding Poly(A) RNA Binding Mitochondrial Light Strand Promoter Sense Binding
	Biological Process	DNA-dependent DNA Replication Chromatin Remodeling Regulation Of Transcription From RNA Polymerase I Promoter Transcription From Mitochondrial Promoter Transcription Initiation From Mitochondrial Promoter Organelle Organization Mitochondrion Organization Gene Expression Mitochondrial Respiratory Chain Complex Assembly Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter
Pathways		Organelle biogenesis and maintenance Mitochondrial transcription initiation RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription Transcription from mitochondrial promoters Transcriptional activation of mitochondrial biogenesis Mitochondrial biogenesis
Drugs
Diseases
GWAS		Height ( 23456168)
Protein-protein Interactions		5 interactors: AGTRAP ARL6IP1 PNP TFB1M TFB2M
Entrez ID		7019
HPRD ID		02702
Ensembl ID		ENSG00000108064
Uniprot IDs		E5KSU5 Q00059
PDB IDs		3FGH 3TMM 3TQ6
Enriched GO Terms of Interacting Partners?		RRNA Methylation RRNA Modification RNA Methylation NAD Biosynthesis Via Nicotinamide Riboside Salvage Pathway Inosine Catabolic Process Nicotinamide Riboside Catabolic Process RRNA Processing RRNA Metabolic Process Interleukin-2 Secretion Urate Biosynthetic Process RNA Modification Transcription Initiation From Mitochondrial Promoter Ribosome Biogenesis Angiotensin-activated Signaling Pathway Ribonucleoprotein Complex Biogenesis Interleukin-2 Production Transcription From Mitochondrial Promoter Urate Metabolic Process Purine Ribonucleoside Catabolic Process Mitochondrion Organization Methylation NcRNA Metabolic Process Regulation Of Appetite Purine-containing Compound Salvage NAD Biosynthetic Process Cytokine Secretion Purine Nucleotide Catabolic Process Purine Nucleobase Metabolic Process Positive Regulation Of Alpha-beta T Cell Differentiation NAD Metabolic Process
Tagcloud ?		analogs apoptogenic biogenesis coded counterpart diminished dissipation doses her2high inducer innovation lowered mitocans mitochondrial mitochondrially mitoves mtdna replicated respiration succinate suppress suppresses targeted tocopheryl transcript transcripts unlike untargeted vitamin