TMBIM6 and VTI1A

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		TMBIM6	VTI1A
Gene Name		transmembrane BAX inhibitor motif containing 6	vesicle transport through interaction with t-SNAREs 1A
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Plasma Membrane Membrane	Golgi Membrane Endosome Endoplasmic Reticulum Membrane Golgi Apparatus Golgi Stack Synaptic Vesicle ER To Golgi Transport Vesicle Membrane Integral Component Of Membrane Clathrin-coated Vesicle SNARE Complex Late Endosome Membrane Neuronal Cell Body Neuron Projection Terminus Perinuclear Region Of Cytoplasm
	Molecular Function		SNARE Binding SNAP Receptor Activity
	Biological Process	Response To Unfolded Protein Endoplasmic Reticulum Calcium Ion Homeostasis Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress Negative Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway	Protein Targeting To Vacuole ER To Golgi Vesicle-mediated Transport Intra-Golgi Vesicle-mediated Transport Golgi To Vacuole Transport Retrograde Transport, Endosome To Golgi Vesicle Fusion With Golgi Apparatus Voluntary Musculoskeletal Movement Golgi Ribbon Formation
Pathways
Drugs
Diseases
GWAS			Lung cancer ( 23143601) Multiple sclerosis ( 23412934) Ventricular conduction ( 21076409)
Protein-Protein Interactions		4 interactors: BCL2 BCL2L1 CERS2 VTI1A	2 interactors: STX16 TMBIM6
Entrez ID		7009	143187
HPRD ID		02851	18290
Ensembl ID		ENSG00000139644	ENSG00000151532
Uniprot IDs		F8W034 P55061	Q96AJ9
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Anoikis Regulation Of Anoikis Release Of Cytochrome C From Mitochondria Negative Regulation Of Autophagy Regulation Of Mitochondrial Membrane Potential Regulation Of Mitochondrial Membrane Permeability Regulation Of Membrane Permeability Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Response To Gamma Radiation Neuron Apoptotic Process Positive Regulation Of Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Mitochondrial Membrane Organization Neuron Death Ovarian Follicle Development Apoptotic Mitochondrial Changes Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Regulation Of Mitochondrion Organization Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Ovulation Cycle Process Negative Regulation Of Intrinsic Apoptotic Signaling Pathway Extrinsic Apoptotic Signaling Pathway Regulation Of Autophagy Female Gonad Development Ovulation Cycle Development Of Primary Female Sexual Characteristics Negative Regulation Of Cellular PH Reduction CD8-positive, Alpha-beta T Cell Lineage Commitment Apoptotic Process In Bone Marrow Negative Regulation Of Retinal Cell Programmed Cell Death Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Membrane Organization Response To Ionizing Radiation Response To Alkaloid Mitochondrial Transport Male Gonad Development Regulation Of Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Neuron Apoptotic Process Intrinsic Apoptotic Signaling Pathway Male Sex Differentiation Intracellular Receptor Signaling Pathway Positive Regulation Of Apoptotic Signaling Pathway Regulation Of Extrinsic Apoptotic Signaling Pathway Negative Regulation Of Neuron Death Vesicle Organization Regulation Of Retinal Cell Programmed Cell Death Positive Regulation Of Neuron Maturation Negative Regulation Of Mitotic Cell Cycle Gonad Development	Golgi Ribbon Formation Negative Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Endoplasmic Reticulum Calcium Ion Homeostasis Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress Intra-Golgi Vesicle-mediated Transport Vesicle Fusion Retrograde Transport, Endosome To Golgi Organelle Fusion Golgi Organization Vesicle Docking Negative Regulation Of Intrinsic Apoptotic Signaling Pathway Membrane Docking
Tagcloud ?		bax belongs beyond branch conserved embryos endoplasmic existence functionally grina homeostasis inositol manipulation melanogaster operating perk regulators reticulum similarly synergies synergistic transmembrane trisphosphate unfolded upregulated zebrafish	attachment claims cognate endosomes ethylmaleimide fairly iialpha owing perinuclear phosphatidylinositol phospholipids pi4k2a promiscuous ptdins4p q recycling reside retrograde segregation shielding snare snares subcellular trafficking transferrin tubulo vamp3 vesicle vesicular
Tagcloud (Difference) ?		bax belongs beyond branch conserved embryos endoplasmic existence functionally grina homeostasis inositol manipulation melanogaster operating perk regulators reticulum similarly synergies synergistic transmembrane trisphosphate unfolded upregulated zebrafish	attachment claims cognate endosomes ethylmaleimide fairly iialpha owing perinuclear phosphatidylinositol phospholipids pi4k2a promiscuous ptdins4p q recycling reside retrograde segregation shielding snare snares subcellular trafficking transferrin tubulo vamp3 vesicle vesicular
Tagcloud (Intersection) ?