TMBIM6

Gene Name		transmembrane BAX inhibitor motif containing 6
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Plasma Membrane Membrane
	Molecular Function
	Biological Process	Response To Unfolded Protein Endoplasmic Reticulum Calcium Ion Homeostasis Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress Negative Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		4 interactors: BCL2 BCL2L1 CERS2 VTI1A
Entrez ID		7009
HPRD ID		02851
Ensembl ID		ENSG00000139644
Uniprot IDs		F8W034 P55061
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Anoikis Regulation Of Anoikis Release Of Cytochrome C From Mitochondria Negative Regulation Of Autophagy Regulation Of Mitochondrial Membrane Potential Regulation Of Mitochondrial Membrane Permeability Regulation Of Membrane Permeability Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Response To Gamma Radiation Neuron Apoptotic Process Positive Regulation Of Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Mitochondrial Membrane Organization Neuron Death Ovarian Follicle Development Apoptotic Mitochondrial Changes Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Regulation Of Mitochondrion Organization Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Ovulation Cycle Process Negative Regulation Of Intrinsic Apoptotic Signaling Pathway Extrinsic Apoptotic Signaling Pathway Regulation Of Autophagy Female Gonad Development Ovulation Cycle Development Of Primary Female Sexual Characteristics Negative Regulation Of Cellular PH Reduction CD8-positive, Alpha-beta T Cell Lineage Commitment Apoptotic Process In Bone Marrow Negative Regulation Of Retinal Cell Programmed Cell Death Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Membrane Organization Response To Ionizing Radiation Response To Alkaloid Mitochondrial Transport Male Gonad Development Regulation Of Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Neuron Apoptotic Process Intrinsic Apoptotic Signaling Pathway Male Sex Differentiation Intracellular Receptor Signaling Pathway Positive Regulation Of Apoptotic Signaling Pathway Regulation Of Extrinsic Apoptotic Signaling Pathway Negative Regulation Of Neuron Death Vesicle Organization Regulation Of Retinal Cell Programmed Cell Death Positive Regulation Of Neuron Maturation Negative Regulation Of Mitotic Cell Cycle Gonad Development
Tagcloud ?		bax belongs beyond branch conserved embryos endoplasmic existence functionally grina homeostasis inositol manipulation melanogaster operating perk regulators reticulum similarly synergies synergistic transmembrane trisphosphate unfolded upregulated zebrafish